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2008-Publications

  1. Abdelmohsen K, Kuwano Y, Kim HH, Gorospe M. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem. 2008;389(3):243-255.

  2. Ahmet I, Krawczyk M, Zhu W, Woo AY, Morrell C, Poosala S, Xiao RP, Lakatta EG, Talan MI. Cardioprotective and survival benefits of long-term combined therapy with {beta}2 AR agonist and {beta}1 AR blocker in dilated cardiomyopathy post-myocardial infarction. J Pharmacol Exp Ther. 2008;325(2):491-499.

  3. Aid S, Langenbach R, Bosetti F. Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2. J Neuroinflammation. 2008;5(1):17.

  4. Anderson DE, Fedorova OV, Morrell CH, Longo DL, Kashkin VA, Metzler JD, Bagrov AY, Lakatta EG. Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives. Am J Physiol Regul Integr Comp Physiol. 2008;294(4):R1248-R1254.

  5. Araki Y, Fann M, Wersto R, Weng NP. Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (Eomesodermin and its targets: Perforin and Granzyme B). J Immunol. 2008;180(12):8102-8108.

  6. Arnaud-Lopez L, Usala G, Ceresini G, Mitchell BD, Pilia MG, Piras MG, Sestu N, Maschio A, Busonero F, Albai G, Dei M, Lai S, Mulas A, Crisponi L, Tanaka T, Bandinelli S, Guralnik JM, Loi A, Balaci L, Sole G, Prinzis A, Mariotti S, Shuldiner AR, Cao A, Schlessinger D, Uda M, Abecasis GR, Nagaraja R, Sanna S, Naitza S. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Am J Hum Genet. 2008;82(6):1270-1280.

  7. Arumugam TV, Selvaraj PK, Woodruff TM, Mattson MP. Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opin Ther Targets. 2008;12(1):19-29.

  8. Bagrov AY, Shapiro JI. Endogenous digitalis: pathophysiologic roles and therapeutic applications. Nat Clin Pract Nephrol. 2008 June. [Epub ahead of print].

  9. Bartali B, Frongillo EA, Guralnik JM, Stipanuk MH, Allore HG, Cherubini A, Bandinelli S, Ferrucci L, Gill TM. Serum micronutrient concentrations and decline in physical function among older persons. JAMA. 2008;299(3):308-315.

  10. Basselin M, Chang L, Chen M, Bell JM, Rapoport SI. Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. Neurochem Res. 2008 May. [Epub ahead of print].

  11. Basselin M, Chang L, Chen M, Bell JM, Rapoport SI. Chronic carbamazepine administration attenuates dopamine D(2)-like receptor-initiated signaling via arachidonic acid in rat brain. Neurochem Res. 2008 Feb.; [Epub ahead of print].

  12. Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nothen MM, Georgi A, Schumacher J, Schwarz M, Abou Jamra R, Hofels S, Propping P, Satagopan J, Detera-Wadleigh SD, Hardy J, McMahon FJ. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry. 2008;13(2):197-207.

  13. Beason-Held LL, Kraut MA, Resnick SM. I. Longitudinal changes in aging brain function. Neurobiol Aging. 2008;29(4):483-496.

  14. Beason-Held LL, Kraut MA, Resnick SM. II. Temporal patterns of longitudinal change in aging brain function. Neurobiol Aging. 2008;29(4):497-513.

  15. Berquist BR, McNeill DR, Wilson DM 3rd. Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision. J Mol Biol. 2008;379(1):17-27.

  16. Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. Imaging apomorphine stimulation of brain arachidonic acid signaling via D(2)-like receptors in unanesthetized rats. Psychopharmacology (Berl). 2008 Feb.; [Epub ahead of print].

  17. Biragyn A, Coscia M, Nagashima K, Sanford M, Young HA, Olkhanud P. Murine {beta}-defensin 2 promotes TLR-4/MyD88-mediated and NF-{kappa}B-dependent atypical death of APCs via activation of TNFR2. J Leukoc Biol. 2008;83(4):998-1008.

  18. Bosetti F, Toscano CD. Is it time to standardize ethics guiding the peer review process? Lipids. 2008;43(2):107-108.

  19. Bras J, Guerreiro R, Ribeiro M, Morgadinho A, Januario C, Dias M, Calado A, Semedo C, Oliveira C, Hardy J, Singleton A. Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2. BMC Neurol. 2008 Jan.;8(1):1 [Epub ahead of print].

  20. Brosh RM Jr. DNA repair as a target for anti-cancer therapy. Anticancer Agents Med Chem. 2008;8(4):350.

  21. Brummett BH, Siegler IC, Day RS, Costa PT. Personality as a predictor of dietary quality in spouses during midlife. Behav Med. 2008;34(1):5-10.

  22. Bugreev DV, Brosh RM Jr, Mazin AV. RECQ1 possesses DNA branch migration activity. J Biol Chem. 2008 May. [Epub ahead of print].

  23. Camargos ST, Cardoso F, Momeni P, Gurgel Gianetti J, Lees A, Hardy J, Singleton A. Novel GCH1 mutation in a Brazilian family with dopa-responsive dystonia. Mov Disord. 2008;23(2):299-302.

  24. Camargos S, Scholz S, Simon-Sanchez J, Paisan-Ruiz C, Lewis P, Hernandez D, Ding J, Gibbs JR, Cookson MR, Bras J, Guerreiro R, Oliveira CR, Lees A, Hardy J, Cardoso F, Singleton AB. DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA. Lancet Neurol. 2008;7(3):207-215.

  25. Cao YJ, Mager DE, Simonsick EM, Hilmer SN, Ling SM, Windham BG, Crentsil V, Yasar S, Fried LP, Abernethy DR. Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women. Clin Pharmacol Ther. 2008;83(3):422-429.

  26. Cardoso CL, de Moraes MC, Carvalho Guido RV, Oliva G, Andricopulo AD, Wainer IW, Cass QB. The development of an immobilized enzyme reactor containing glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi: the effect of species' specific differences on the immobilization. Analyst. 2008;133(1):93-99.

  27. Carter MG, Stagg CA, Falco G, Yoshikawa T, Bassey UC, Aiba K, Sharova LV, Shaik N, Ko MS. An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells. Gene Expr Patterns. 2008;8(3):181-198.

  28. Casolaro V, Fang X, Tancowny B, Fan J, Wu F, Srikantan S, Asaki SY, De Fanis U, Huang SK, Gorospe M, Atasoy UX, Stellato C. Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR. J Allergy Clin Immunol. 2008 Feb.; [Epub ahead of print].

  29. Cecchi F, Mannoni A, Molino-Lova R, Ceppatelli S, Benvenuti E, Bandinelli S, Lauretani F, Macchi C, Ferrucci L. Epidemiology of hip and knee pain in a community based sample of Italian persons aged 65 and older. Osteoarthritis Cartilage. 2008 Mar.; [Epub ahead of print].

  30. Chang YC, Kim HW, Rapoport SI, Rao JS. Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation. Neurochem Res. 2008 May. [Epub ahead of print].

  31. Chantler PD, Melenovsky V, Schulman SP, Gerstenblith G, Becker LC, Ferrucci L, Fleg JL, Lakatta EG, Najjar SS. The sex-specific impact of systolic hypertension and systolic blood pressure on arterial-ventricular coupling at rest and during exercise. Am J Physiol Heart Circ Physiol. 2008 May. [Epub ahead of print].

  32. Chen J, Xiao L, Rao JN, Zou T, Liu L, Bellavance E, Gorospe M, Wang JY. JunD represses transcription and translation of the tight junction protein ZO-1 modulating intestinal epithelial barrier function. Mol Biol Cell. 2008 June. [Epub ahead of print].

  33. Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orru M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jørgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest. 2008 June. [Epub ahead of print].

  34. Chiara F, Castellaro D, Marin O, Petronilli V, Brusilow WS, Juhaszova M, Sollott SJ, Forte M, Bernardi P, Rasola A. Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. PLoS ONE. 2008;3(3):e1852.

  35. Choi SH, Langenbach R, Bosetti F. Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury. FASEB J. 2008;22(5):1491-1501.

  36. Cookson MR, van der Brug M. Cell systems and the toxic mechanism(s) of alpha-synuclein. Exp Neurol. 2008;209(1):5-11.

  37. Csiszar A, Labinskyy N, Podlutsky A, Kaminski PM, Wolin MS, Zhang C, Mukhopadhyay P, Pacher P, Hu F, de Cabo R, Ballabh P, Ungvari Z. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol. 2008;294(6):H2721-H2735.

  38. Dahiya N, Sherman-Baust CA, Wang TL, Davidson B, Shih IeM, Zhang Y, Wood W 3rd, Becker KG, Morin PJ. MicroRNA expression and identification of putative miRNA targets in ovarian cancer. PLoS ONE. 2008;3(6):e2436.

  39. Davatzikos C, Fan Y, Wu X, Shen D, Resnick SM. Detection of prodromal Alzheimer's disease via pattern classification of magnetic resonance imaging. Neurobiol Aging. 2008;29(4):514-523.

  40. Dawson HD, Collins G, Pyle R, Key M, Taub DD. Retinoic acid receptor-alpha mediates human T-cell activation and Th2 cytokine production. BMC Immunol. 2008 Apr.;9(1):16 [Epub ahead of print].

  41. Dayhoff-Brannigan M, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with elevated serum interleukin-6 levels among older moderately to severely disabled women living in the community. J Gerontol A Biol Sci Med Sci. 2008;63(2):179-183.

  42. Deng J, Lewis PA, Greggio E, Sluch E, Beilina A, Cookson MR. Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase. Proc Natl Acad Sci USA. 2008;105(5):1499-1504.

  43. Deo R, Wassel Fyr CL, Fried LF, Newman AB, Harris TB, Angleman S, Green C, Kritchevsky SB, Chertow GM, Cummings SR, Shlipak MG; for the Health ABC study. Kidney dysfunction and fatal cardiovascular disease-an association independent of atherosclerotic events: Results from the Health, Aging, and Body Composition (Health ABC) study. Am Heart J. 2008;155(1):62-68.

  44. Deshpande N, Metter EJ, Bandinelli S, Lauretani F, Windham BG, Ferrucci L. Psychological, physical, and sensory correlates of fear of falling and consequent activity restriction in the elderly: The InCHIANTI Study. Am J Phys Med Rehabil. 2008;87(5):354-362.

  45. Deshpande N, Metter EJ, Lauretani F, Bandinelli S, Guralnik J, Ferrucci L. Activity restriction induced by fear of falling and objective and subjective measures of physical function: a prospective cohort study. J Am Geriatr Soc. 2008;56(4):615-620.

  46. Deshpande N, Metter EJ, Ling S, Conwit R, Ferrucci L. Physiological correlates of age-related decline in vibrotactile sensitivity. Neurobiol Aging. 2008;29(5):765-773.

  47. de Souza-Pinto NC, Wilson DM 3rd, Stevnsner TV, Bohr VA. Mitochondrial DNA, base excision repair and neurodegeneration. DNA Repair (Amst). 2008 May. [Epub ahead of print].

  48. Di Bari M, Pecchioli A, Mazzaglia G, Marini M, Maciocco G, Ferrucci L, Marchionni N. Care available to severely disabled older persons living at home in Florence, Italy. Aging Clin Exp Res. 2008;20(1):31-39.

  49. Ding J, Kritchevsky SB, Harris TB, Burke GL, Detrano RC, Szklo M, Jeffrey Carr J; for the Multi-Ethnic Study of Atherosclerosis. The association of pericardial fat with calcified coronary plaque. Obesity (Silver Spring). 2008 May. [Epub ahead of print].

  50. Dotson VM, Resnick SM, Zonderman AB. Differential association of concurrent, baseline, and average depressive symptoms with cognitive decline in older adults. Am J Geriatr Psychiatry. 2008;16(4):318-330.

  51. Earley CJ, Ponnuru P, Wang X, Patton SM, Conner JR, Beard JL, Taub DD, Allen RP. Altered iron metabolism in lymphocytes from subjects with restless legs syndrome. Sleep. 2008;31(6):847-852.

  52. Egan JM, Margolskee RF. Taste cells of the gut and gastrointestinal chemosensation. Mol Interv. 2008;8(2):78-81.

  53. Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 2008 April; [Epub ahead of print].

  54. Fan Y, Resnick SM, Wu X, Davatzikos C. Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study. Neuroimage. 2008; [Epub ahead of print].

  55. Farasat SM, Morrell CH, Scuteri A, Ting C-T, Yin FCP, Spurgeon HA, Chen C-H, Lakatta EG, Najjar SS. Pulse pressure is inversely related to aortic root diameter: implications for the pathogenesis of systolic hypertension. Hypertension. 2008;51:196-202.

  56. Farias SE, Basselin M, Chang L, Heidenreich KA, Rapoport SI, Murphy RC. Formation of eicosanoids, E2/D2-isoprostanes and docosanoids following decapitation-induced ischemia, measured in high-energy microwaved rat brain. J Lipid Res. 2008 May. [Epub ahead of print].

  57. Ferrucci L. Throwing pots and commitments for 2008. J Gerontol A Biol Sci Med Sci. 2008;63(2):157-159.

  58. Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS ONE. 2008;3(4):e2020.

  59. Fleg JL and Lakatta EG. Normal Aging of the Cardiovascular System. Chapter in Cardiovascular Disease in the Elderly. Fourth edition. Wilbert Aronow, Michael W. Rich, Jerome L. Fleg, eds. CRC Press, Boca Raton, Florida. 2008:1-43.

  60. Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM. Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected, given its effect on BMI. Diabetes. 2008 Mar.; [Epub ahead of print].

  61. Furey ML, Ricciardi E, Schapiro MB, Rapoport SI, Pietrini P. Cholinergic enhancement eliminates modulation of neural activity by task difficulty in the prefrontal cortex during working memory. J Cogn Neurosci. 2008 Feb.; [Epub ahead of print].

  62. Galban S, Kuwano Y, Pullmann R Jr, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor-1{alpha} Mol Cell Biol. 2008;28(1):93-107.

  63. Giles JT, Ling SM, Ferrucci L, Bartlett SJ, Andersen RE, Towns M, Muller D, Fontaine KR, Bathon JM. Abnormal body composition phenotypes in older rheumatoid arthritis patients: Association with disease characteristics and pharmacotherapies. Arthritis Rheum. 2008;59(6):807-815.

  64. Goldman SE, Hall M, Boudreau R, Matthews KA, Cauley JA, Ancoli-Lsrael S, Stone KL, Rubin SM, Satterfield S, Simonsick EM, Newman AB. Association between nighttime sleep and napping in older adults. Sleep. 2008;31(5):733-740.

  65. Gong F, Fahy D, Liu H, Wang W, Smerdon MJ. Role of the mammalian SWI/SNF chromatin remodeling complex in the cellular response to UV damage. Cell Cycle. 2008;7(8). [Epub ahead of print].

  66. Gorospe M, de Cabo R. AsSIRTing the DNA damage response. Trends Cell Biol. 2008;18(2):77-83.

  67. Greggio E, Zambrano I, Kaganovich A, Beilina A, Taymans JM, Daniëls V, Lewis P, Jain S, Ding J, Syed A, Thomas KJ, Baekelandt V, Cookson MR. The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J Biol Chem. 2008;283(24):16906-16914.

  68. Grober E, Hall CB, Lipton RB, Zonderman AB, Resnick SM, Kawas C. Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease. J Int Neuropsychol Soc. 2008;14(2):266-278.

  69. Guerreiro RJ, Santana I, Bras JM, Revesz T, Rebelo O, Ribeiro MH, Santiago B, Oliveira CR, Singleton A, Hardy J. Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases. Mov Disord. 2008 May. [Epub ahead of print].

  70. Guerreiro RJ, Schymick JC, Crews C, Singleton A, Hardy J, Traynor BJ. TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis. PLoS ONE. 2008;3(6):e2450.

  71. Guilarte TR, Burton NC, Verina T, Prabhu VV, Becker KG, Syversen T, Schneider JS. Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. J Neurochem. 2008 Feb.; [Epub ahead of print].

  72. Gupta R, Brosh RM Jr. Helicases as prospective targets for anti-cancer therapy. Anticancer Agents Med Chem. 2008;8(4):390-401.

  73. Guralnik JM. Successful aging: is it in our future? Arch Intern Med. 2008;168(2):131-132.

  74. Haque ME, Thomas KJ, D'Souza C, Callaghan S, Kitada T, Slack RS, Fraser P, Cookson MR, Tandon A, Park DS. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci USA. 2008;105(5):1716-1721.

  75. Harel A, Wu F, Mattson MP, Morris CM, Yao PJ. Evidence for CALM in directing VAMP2 trafficking. Traffic. 2008;9(3):417-429.

  76. Hashimoto T, Schlessinger D, Cui CY. Troy binding to lymphotoxin-alpha activates NFkappaB mediated transcription. Cell Cycle. 2008;7(1):106-111.

  77. Heltemes-Harris LM, Gearhart PJ, Ghosh P, Longo DL. Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion. Mol Immunol. 2008;45(6):1799-1806.

  78. Hicks GE, Shardell M, Miller RR, Bandinelli S, Guralnik J, Cherubini A, Lauretani F, Ferrucci L. Associations between vitamin D status and pain in older adults: The Invecchiare InChianti Study. J Am Geriatr Soc. 2008 Mar.; [Epub ahead of print].

  79. Hill JW, Hu JJ, Evans MK. OGG1 is degraded by calpain following oxidative stress and cisplatin exposure. DNA Repair (Amst). 2008;7(4):648-654.

  80. Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, Laferla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Res. 2008 April. [Epub ahead of print].

  81. Holden KF, Lindquist K, Tylavsky FA, Rosano C, Harris TB, Yaffe K; for the Health ABC study. Serum leptin level and cognition in the elderly: Findings from the Health ABC Study. Neurobiol Aging. 2008 March; [Epub ahead of print].

  82. Hossain MZ, Yu Q, Xu M, Sen JM. ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells. Int Immunol. 2008;20(7):925-935.

  83. Hourani R, Brant LJ, Rizk T, Weingart JD, Barker PB, Horská A. Can proton MR spectroscopic and perfusion imaging differentiate between neoplastic and nonneoplastic brain lesions in adults? AJNR Am J Neuroradiol. 2008;29(2):366-372.

  84. Houston DK, Nicklas BJ, Ding J, Harris TB, Tylavsky FA, Newman AB, Lee JS, Sahyoun NR, Visser M, Kritchevsky SB; for the Health ABC Study. Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr. 2008;87(1):150-155.

  85. Huang MC, Liao JJ, Bonasera S, Longo DL, Goetzl EJ. Nuclear factor-{kappa}B-dependent reversal of aging-induced alterations in T cell cytokines. FASEB J. 2008 Feb.; [Epub ahead of print].

  86. Hyun M, Bohr VA, Ahn B. Biochemical characterization of the WRN-1 RecQ helicase of caenorhabditis elegans. Biochemistry. 2008 June. [Epub ahead of print].

  87. Hyun M, Lee J, Lee K, May A, Bohr VA, Ahn B. Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans. Nucleic Acids Res. 2008;36(4):1380-1389.

  88. Iacono D, O’Brien R, Resnick SM, Zonderman AB, Pletnikova O, Rudow G, An Y, West MJ, Crain B, Troncoso JC. Neuronal hypertrophy in asymptomatic Alzheimer disease. J Neuropathol Exp Neurol. 2008;67(6):578-589.

  89. Igarashi M, Ma K, Chang L, Bell JM, Rapoport SI. Rat heart cannot synthesize docosahexaenoic acid from circulating alpha -linolenic acid because it lacks elongase-2. J Lipid Res. 2008 May. [Epub ahead of print].

  90. Irie F, Fitzpatrick AL, Lopez OL, Kuller LH, Peila R, Newman AB, Launer LJ. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE {varepsilon}4: The Cardiovascular Health Study Cognition Study. Arch Neurol. 2008;65(1):89-93.

  91. Ironson GH, O'Cleirigh C, Weiss A, Schneiderman N, Costa PT Jr. Personality and HIV disease progression: role of NEO-PI-R openness, extraversion, and profiles of engagement. Psychosom Med. 2008;70(2):245-253.

  92. Ishmael FT, Fang X, Galdiero MR, Atasoy U, Rigby WF, Gorospe M, Cheadle C, Stellato C. Role of the RNA-binding protein Tristetraprolin in glucocorticoid-mediated gene regulation. J Immunol. 2008;180(12):8342-8353.

  93. Jakobsson M, Scholz SW, Scheet P, Gibbs JR, VanLiere JM, Fung HC, Szpiech ZA, Degnan JH, Wang K, Guerreiro R, Bras JM, Schymick JC, Hernandez DG, Traynor BJ, Simon-Sanchez J, Matarin M, Britton A, van de Leemput J, Rafferty I, Bucan M, Cann HM, Hardy JA, Rosenberg NA, Singleton AB. Genotype, haplotype and copy-number variation in worldwide human populations. Nature. 2008;451(7181):998-1003.

  94. Jarvik L, Larue A, Blacker D, Gatz M, Kawas C, McArdle JJ, Morris JC, Mortimer JA, Ringman JM, Ercoli L, Freimer N, Gokhman I, Manly JJ, Plassman BL, Rasgon N, Roberts JS, Sunderland T, Swan GE, Wolf PA, Zonderman AB. Children of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008;22(1):6-20.

  95. Jiang L, Wang M, Zhang J, Monticone RE, Telljohann R, Spinetti G, Pintus G, Lakatta EG. Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells. PLoS ONE. 2008;3(5):e2231.

  96. Juhaszova M, Wang S, Zorov DB, Nuss HB, Gleichmann M, Mattson MP, Sollott SJ. The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown. Ann NY Acad Sci. 2008: 1123:197-212.

  97. Kamal MA, Klein P, Luo W, Li Y, Holloway HW, Tweedie D, Greig NH. Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine. Neurochem Res. 2008;33(5):745-753.

  98. Kamal MA, Qu X, Yu QS, Tweedie D, Holloway HW, Li Y, Tan Y, Greig NH. Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis. J Neural Transm. 2008 Jan.; [Epub ahead of print].

  99. Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine JC, de Cabo R, Cohen HY. Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett. 2008; 582(5):543-548.

  100. Kashkin VA, Zvartau EE, Fedorova OV, Bagrov YY, Lakatta EG, Bagrov AY. Endogenous bufadienolide mediates pressor response to ethanol withdrawal in rats. Eur Neuropsychopharmacol. 2008;18(1):74-77.

  101. Kennedy DJ, Elkareh J, Shidyak A, Shapiro AP, Smaili S, Mutgi K, Gupta S, Tian J, Morgan E, Khouri S, Cooper CJ, Periyasamy SM, Xie Z, Malhotra D, Fedorova OV, Bagrov AY, Shapiro JI. Partial nephrectomy as a model for uremic cardiomyopathy in the mouse. Am J Physiol Renal Physiol. 2008;294(2):F450-F454.

  102. Kiefmann R, Rifkind JM, Nagababu E, Bhattacharya J. Red blood cells induce hypoxic lung inflammation. Blood. 2008;111(10):5205-5214.

  103. Kim HH, Gorospe M. GU-rich RNA: Expanding CUGBP1 function, broadening mRNA turnover. Mol Cell. 2008;29(2):151-152.

  104. Komatsu T, Chiba T, Yamaza H, Yamashita K, Shimada A, Hoshiyama Y, Henmi T, Ohtani H, Higami Y, de Cabo R, Ingram DK, Shimokawa I. Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8. Exp Gerontol. 2008;43(4):339-346.

  105. Konecny GE, Agarwal R, Keeney GA, Winterhoff B, Jones MB, Mariani A, Riehle D, Neuper C, Dowdy SC, Wang HJ, Morin PJ, Podratz KC. Claudin-3 and claudin-4 expression in serous papillary, clear-cell, and endometrioid endometrial cancer. Gynecol Oncol. 2008 Feb.; [Epub ahead of print].

  106. Koster A, Leitzmann MF, Schatzkin A, Mouw T, Adams KF, van Eijk JT, Hollenbeck AR, Harris TB. Waist circumference and mortality. Am J Epidemiol. 2008 April; [Epub ahead of print].

  107. Koster A, Patel KV, Visser M, van Eijk JT, Kanaya AM, de Rekeneire N, Newman AB, Tylavsky FA, Kritchevsky SB, Harris TB; for the Health, Aging and Body Composition Study. Joint effects of adiposity and physical activity on incident mobility limitation in older adults. J Am Geriatr Soc. 2008;56(4):636-643.

  108. Kothapalli N, Norton DD, Fugmann SD. Cutting Edge: A cis-Acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus. J Immunol. 2008;180(4):2019-2023.

  109. Krasnova IN, Li SM, Wood WH, McCoy MT, Prabhu VV, Becker KG, Katz JL, Cadet JL. Transcriptional responses to reinforcing effects of cocaine in the rat hippocampus and cortex. Genes Brain Behav. 2008;7(2):193-202.

  110. Kraut MA, Beason-Held LL, Elkins WD, Resnick SM. The impact of magnetic resonance imaging-detected white matter hyperintensities on longitudinal changes in regional cerebral blood flow. J Cereb Blood Flow Metab. 2008;28(1):190-197.

  111. Kulkarni A, Wilson DM 3rd. The involvement of DNA-damage and -repair defects in neurological dysfunction. Am J Hum Genet. 2008;82(3):539-566.

  112. Kusumoto R, Dawut L, Marchetti C, Wan Lee J, Vindigni A, Ramsden D, Bohr VA. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing. Biochemistry. 2008 June. [Epub ahead of print].

  113. Kuwano Y, Kim HH, Abdelmohsen K, Pullmann R Jr, Martindale JL, Yang X, Gorospe M. MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol. 2008 May. [Epub ahead of print].

  114. Lakatta EG, Najjar SS, Schulman SP, Gestenblith G. Cardiovascular aging in the absence of clinical disease, and therapeutic considerations for older patients with clinical cardiovascular diseases. In Hurst's The Heart, 12th edition. Fuster V, O'Rourke RA, Walsh RA, Poole-Wilson PA (editors). McGraw-Hill Medical, New York, 2008. Chapter 101, pp. 2247-2274.

  115. Lakatta EG, Vinogradova T, Maltsev VA. The missing link in solving the mystery of normal automaticity of cardiac pacemaker cells. Ann NY Acad Sci. 2008; 1123:41-57.

  116. Lal A, Kim HH, Abdelmohsen K, Kuwano Y, Pullmann R Jr, Srikantan S, Subrahmanyam R, Martindale JL, Yang X, Ahmed F, Navarro F, Dykxhoorn D, Lieberman J, Gorospe M. p16(INK4a) translation suppressed by miR-24. PLoS ONE. 2008;3(3):e1864.

  117. Lane R, Feldman HH, Meyer J, He Y, Ferris SH, Nordberg A, Darreh-Shori T, Soininen H, Pirttilä T, Farlow MR, Sfikas N, Ballard C, Greig NH. Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease. Pharmacogenet Genomics. 2008;18(4):289-298.

  118. Lao QZ, Kobrinsky E, Harry JB, Ravindran A, Soldatov NM. New determinant for the Cavbeta 2-subunit modulation of the Cav1.2 calcium channel. J Biol Chem. 2008 April; [Epub ahead of print].

  119. Lao Z, Shen D, Liu D, Jawad AF, Melhem ER, Launer LJ, Bryan RN, Davatzikos C. Computer-assisted segmentation of white matter lesions in 3D MR images using support vector machine. Acad Radiol. 2008;15(3):300-313.

  120. Lauretani F, Semba RD, Bandinelli S, Dayhoff-Brannigan M, Giacomini V, Corsi AM, Guralnik JM, Ferrucci L. Low plasma carotenoids and skeletal muscle strength decline over 6 years. J Gerontol A Biol Sci Med Sci. 2008;63(4):376-383.

  121. Lauretani F, Semba RD, Bandinelli S, Miller ER 3rd, Ruggiero C, Cherubini A, Guralnik JM, Ferrucci L. Plasma polyunsaturated fatty acids and the decline of renal function. Clin Chem. 2008 Jan.; [Epub ahead of print].

  122. Laurin D, David Curb J, Masaki KH, White LR, Launer LJ. Midlife C-reactive protein and risk of cognitive decline: A 31-year follow-up. Neurobiol Aging. 2008 Mar.; [Epub ahead of print].

  123. Le Couteur DG, Warren A, Cogger VC, Smedsrod B, Sorensen KK, de Cabo R, Fraser R, McCuskey RS. Old age and the hepatic sinusoid. Anat Rec (Hoboken). 2008;291(6):672-683.

  124. Lecona E, Olmo N, Turnay J, Santiago-Gomez A, Lopez de Silanes I, Gorospe M, Lizarbe MA. Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms. Biochem J. 2008;409(1):311-320.

  125. Lee HJ, Rao JS, Chang L, Rapoport SI, Bazinet RP. Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat. J Lipid Res. 2008;49(1):162-168.

  126. Lettre G, Jackson AU, Gieger C, Schumacher FR, Berndt SI, Sanna S, Eyheramendy S, Voight BF, Butler JL, Guiducci C, Illig T, Hackett R, Heid IM, Jacobs KB, Lyssenko V, Uda M; The Diabetes Genetics Initiative; FUSION; KORA; The Prostate, Lung Colorectal and Ovarian Cancer Screening Trial; The Nurses' Health Study; SardiNIA, Boehnke M, Chanock SJ, Groop LC, Hu FB, Isomaa B, Kraft P, Peltonen L, Salomaa V, Schlessinger D, Hunter DJ, Hayes RB, Abecasis GR, Wichmann HE, Mohlke KL, Hirschhorn JN. Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet. 2008 April; [Epub ahead of print].

  127. Li H, Xuan J, Wang Y, Zhan M. Inferring regulatory networks. Front Biosci. 2008;13:263-275.

  128. Li Y, Zhang F, Nagai N, Tang Z, Zhang S, Scotney P, Lennartsson J, Zhu C, Qu Y, Fang C, Hua J, Matsuo O, Fong GH, Ding H, Cao Y, Becker KG, Nash A, Heldin CH, Li X. VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats. J Clin Invest. 2008;118(3):913-923.

  129. Ling SM. Does acupuncture improve symptoms in patients with osteoarthritis who are awaiting knee replacement surgery? Nat Clin Pract Rheumatol. 2008 April. [Epub ahead of print].

  130. Litman R, Gupta R, Brosh RM Jr, Cantor SB. BRCA-FA pathway as a target for anti-tumor drugs. Anticancer Agents Med Chem. 2008;8(4):426-430.

  131. Liu M, Liang Y, Chigurupati S, Lathia JD, Pletnikov M, Sun Z, Crow M, Ross CA, Mattson MP, Rabb H. Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol. 2008 April; [Epub ahead of print].

  132. Liu P, Qian L, Sung JS, de Souza-Pinto NC, Zheng L, Bogenhagen DF, Bohr VA, Wilson DM 3rd, Shen B, Demple B. Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria. Mol Cell Biol. 2008 June. [Epub ahead of print].

  133. Liu Y, Bohr VA, Lansdorp P. Telomere, telomerase and aging. Mech Ageing Dev. 2008;129(1-2):1-2.

  134. Lockenhoff CE, Costa PT Jr, Lane RD. Age differences in descriptions of emotional experiences in oneself and others. J Gerontol B Psychol Sci Soc Sci. 2008;63(2):P92-P99.

  135. Loos RJ, Nagaraja R, Schlessinger D, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008 May. [Epub ahead of print].

  136. Luo D, Yang D, Lan X, Li K, Li X, Chen J, Zhang Y, Xiao R.P, Han Q, Cheng H. Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-triphosphate receptors in neonatal rat cardiomyocytes. Cell Calcium. 2008;43:165-174.

  137. Macchi C, Molino-Lova R, Polcaro P, Guarducci L, Lauretani F, Cecchi F, Bandinelli S, Guralnik JM, Ferrucci L. Higher circulating levels of uric acid are prospectively associated with better muscle function in older persons. Mech Ageing Dev. 2008. [Epub ahead of print].

  138. Magnus T, Carmen J, Deleon J, Xue H, Pardo AC, Lepore AC, Mattson MP, Rao MS, Maragakis NJ. Adult glial precursor proliferation in mutant SOD1(G93A) mice. Glia. 2008;56(2):200-208.

  139. Majumdar A, Muniandy PA, Liu J, Liu JL, Liu ST, Cuenoud B, Seidman MM. Targeted gene knock-in and sequence modulation mediated by a psoralen linked triplex forming oligonucleotide. J Biol Chem. 2008 Feb.; [Epub ahead of print].

  140. Maltsev VA, Lakatta EG. Dynamic interactions of an intracellular Ca2+ clock and membrane ion channel clock underlie robust initiation and regulation of cardiac pacemaker function. Cardiovasc Res. 2008;77:274-284.

  141. Maltsev VA, Undrovinas A. Late sodium current in failing heart: Friend or foe? Prog Biophys Mol Biol. 2008;96(1-3):421-451.

  142. Marszall MP, Moaddel R, Jozwiak K, Bernier M, Wainer IW. Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities. Anal Biochem. 2008;373(2):313-321.

  143. Martin B, Golden E, Carlson OD, Egan JM, Mattson MP, Maudsley S. Caloric restriction: Impact upon pituitary function and reproduction. Ageing Res Rev. 2008 Feb.; [Epub ahead of print].

  144. Martin B, Golden E, Keselman A, Stone M, Mattson MP, Egan JM, Maudsley S. Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body. Histol Histopathol. 2008;23(2):237-250.

  145. Martin B, Pearson M, Brenneman R, Golden E, Keselman A, Iyun T, Carlson OD, Egan JM, Becker KG, Wood W 3rd, Prabhu V, de Cabo R, Maudsley S, Mattson MP. Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males. PLoS ONE. 2008;3(6):e2398.

  146. Martomo SA, Saribasak H, Yokoi M, Hanaoka F, Gearhart PJ. Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst). 2008 May. [Epub ahead of print].

  147. Mast BT, Miles T, Penninx BW, Yaffe K, Rosano C, Satterfield S, Ayonayon HN, Harris T, Simonsick EM. Vascular disease and future risk of depressive symptomatology in older adults: Findings from Health, Aging and Body Composition. Biol Psychiatry. 2008 Mar.; [Epub ahead of print].

  148. Masui S, Ohtsuka S, Yagi R, Takahashi K, Ko MS, Niwa H. Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells. BMC Dev Biol. 2008;8:45.

  149. Matarin M, Brown WM, Hardy JA, Rich SS, Singleton AB, Brown RD Jr, Brott TG, Worrall BB, Meschia JF. Association of integrin alpha2 gene variants with ischemic stroke. J Cereb Blood Flow Metab. 2008;22(12):1862-1868.

  150. Matarin M, Simon-Sanchez J, Fung HC, Scholz S, Gibbs JR, Hernandez DG, Crews C, Britton A, Wavrant De Vrieze F, Brott TG, Brown RD Jr, Worrall BB, Silliman S, Case LD, Hardy JA, Rich SS, Meschia JF, Singleton AB. Structural genomic variation in ischemic stroke. Neurogenetics. 2008;9(2):101-108.

  151. Mattapallil MJ, Augello A, Cheadle C, Teichberg D, Becker KG, Chan CC, Mattapallil JJ, Pennesi G, Caspi RR. Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2008;49(5):1957-1970.

  152. Mattson MP. Hormesis defined. Ageing Res Rev. 2008;7(1):1-7.

  153. Mattson MP, van Praag H. TAGing APP constrains neurogenesis. Nat Cell Biol. 2008;10(3):249-250.

  154. Mattson MP, Wan R. Neurotrophic factors in autonomic nervous system plasticity and dysfunction. Neuromolecular Med. 2008 Jan.; [Epub ahead of print].

  155. Maynard S, Swistikowa AM, Lee JW, Liu Y, Liu ST, DA Cruz A, Rao M, de Souza-Pinto N, Zeng X, Bohr VA. Human embryonic stem cells have enhanced repair of multiple forms of DNA damage. Stem Cells. 2008 June. [Epub ahead of print].

  156. McCrae RR. A note on some measures of profile agreement. J Pers Assess. 2008;90(2):105-109.

  157. McDermott MM, Guralnik JM, Ferrucci L, Tian L, Liu K, Liao Y, Green D, Sufit R, Hoff F, Nishida T, Sharma L, Pearce WH, Schneider JR, Criqui MH. Asymptomatic peripheral arterial disease is associated with more adverse lower extremity characteristics than intermittent claudication. Circulation. 2008;117(19):2484-2491.

  158. McDermott MM, Tian L, Ferrucci L, Liu K, Guralnik JM, Liao Y, Pearce WH, Criqui MH. Associations between lower extremity ischemia, upper and lower extremity strength, and functional impairment with peripheral arterial disease. J Am Geriatr Soc. 2008 Feb.; [Epub ahead of print].

  159. McDermott MM, Tian L, Liu K, Guralnik JM, Ferrucci L, Tan J, Pearce WH, Schneider JR, Criqui MH. Prognostic value of functional performance for mortality in patients with peripheral artery disease. J Am Coll Cardiol. 2008;51(15):1482-1489.

  160. McNeely JD, Windham BG, Anderson DE. Dietary sodium effects on heart rate variability in salt sensitivity of blood pressure. Psychophysiology. 2008;45(3):405-411.

  161. Melzer D, Perry JR, Hernandez D, Corsi AM, Stevens K, Rafferty I, Lauretani F, Murray A, Gibbs JR, Paolisso G, Rafiq S, Simon-Sanchez J, Lango H, Scholz S, Weedon MN, Arepalli S, Rice N, Washecka N, Hurst A, Britton A, Henley W, van de Leemput J, Li R, Newman AB, Tranah G, Harris T, Panicker V, Dayan C, Bennett A, McCarthy MI, Ruokonen A, Jarvelin MR, Guralnik J, Bandinelli S, Frayling TM, Singleton A, Ferrucci L. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. 2008;4(5):e1000072.

  162. Metter EJ, Windham BG, Maggio M, Simonsick EM, Ling SM, Egan JM, Ferrucci L. Glucose and insulin measurements from the glucose tolerance test and mortality prediction. Diabetes Care. 2008 Feb.; [Epub ahead of print].

  163. Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 2008;452(7186):492-496.

  164. Miller RS, Becker KG, Prabhu V, Cooke DW. Adipocyte gene expression is altered in formerly obese mice and as a function of diet composition. J Nutr. 2008;138(6):1033-1038.

  165. Milligan LA, Rapoport SI, Cranfield MR, Dittus W, Glander KE, Oftedal OT, Power ML, Whittier CA, Bazinet RP. Fatty acid composition of wild anthropoid primate milks. Comp Biochem Physiol B Biochem Mol Biol. 2008;149(1):74-82.

  166. Minor RK, Villarreal J, McGraw M, Percival SS, Ingram DK, de Cabo R. Calorie restriction alters physical performance but not cognition in two models of altered neuroendocrine signaling. Behav Brain Res. 2008;189(1):202-211.

  167. Mitchell GF, Gudnason V, Launer LJ, Aspelund T, Harris TB. Hemodynamics of increased pulse pressure in older women in the community-based age, Gene/Environment Susceptibility-Reykjavik Study. Hypertension. 2008 Feb.; [Epub ahead of print].

  168. Moaddel R, Oliveira RV, Kimura T, Hyppolite P, Juhaszova M, Xiao Y, Kellar KJ, Bernier M, Wainer IW. Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Anal Chem. 2008;80(1):48-54.

  169. Mohanty JG, Eckley DM, Williamson JD, Launer LJ, Rifkind JM. Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease? Adv Exp Med Biol. 2008;614:29-35.

  170. Morin PJ. Learning about ovarian tumorigenesis by watching cables. Cancer Biol Ther. 2008;7(2).

  171. Morley JE, Ferrucci L. Publication productivity in geriatrics: 1995-2006. J Gerontol A Biol Sci Med Sci. 2008;63(6):584-585.

  172. Movsesyan N, Ghochikyan A, Mkrtichyan M, Petrushina I, Davtyan H, Olkhanud PB, Head E, Biragyn A, Cribbs DH, Agadjanyan MG. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS ONE. 2008;3(5):e2124.

  173. Muftuoglu M, Kusumoto R, Speina E, Beck G, Cheng WH, Bohr VA. Acetylation regulates WRN catalytic activities and affects base excision DNA repair. PLoS ONE. 2008;3(4):e1918.

  174. Nagababu E, Fabry ME, Nagel RL, Rifkind JM. Heme degradation and oxidative stress in murine models for hemoglobinopathies: Thalassemia, sickle cell disease and hemoglobin C disease. Blood Cells Mol Dis. 2008 Feb.; [Epub ahead of print].

  175. Najjar SS, Scuteri A, Shetty V, Wright JG, Muller DC, Fleg JL, Spurgeon HP, Ferrucci L, Lakatta EG. Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging. J Am Coll Cardiol. 2008;51(14):1377-1383.

  176. Nalls MA, Wilson JG, Patterson NJ, Tandon A, Zmuda JM, Huntsman S, Garcia M, Hu D, Li R, Beamer BA, Patel KV, Akylbekova EL, Files JC, Hardy CL, Buxbaum SG, Taylor HA, Reich D, Harris TB, Ziv E. Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the Health ABC and Jackson Heart studies. Am J Hum Genet. 2008;82(1):81-87.

  177. Nestadt G, Costa PT Jr, Hsu FC, Samuels J, Bienvenu OJ, Eaton WW. The relationship between the five-factor model and latent Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition personality disorder dimensions. Compr Psychiatry. 2008;49(1):98-105.

  178. Newman AB, Boudreau RM, Naydeck BL, Fried LF, Harris TB. A physiologic index of comorbidity: relationship to mortality and disability. J Gerontol A Biol Sci Med Sci. 2008;63(6):603-609.

  179. Paap B, Wilson DM 3rd, Sutherland BM. Human abasic endonuclease action on multilesion abasic clusters: implications for radiation-induced biological damage. Nucleic Acids Res. 2008 Mar.; [Epub ahead of print].

  180. Paisan-Ruiz C, Nath P, Washecka N, Gibbs JR, Singleton AB. Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls. Hum Mutat. 2008;29(4):485-490.

  181. Panicker V, Cluett C, Shields B, Murray A, Parnell KS, Perry JR, Weedon MN, Singleton A, Hernandez D, Evans J, Durant C, Ferrucci L, Melzer D, Saravanan P, Visser TJ, Ceresini G, Hattersley AT, Vaidya B, Dayan CM, Frayling TM. A Common variation in Deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triidothyronine. J Clin Endocrinol Metab. 2008 May. [Epub ahead of print].

  182. Patel KV, Harris TB, Newman AB, Guralnik JM. Further epidemiologic research on anemia in older adults is needed. Blood. 2008;111(5):2941-2942.

  183. Pchelina SN, Yakimovskii AF, Emelyanov AK, Ivanova ON, Schwarzman AL, Singleton AB. Screening for LRRK2 mutations in patients with Parkinson's disease in Russia: identification of a novel LRRK2 variant. Eur J Neurol. 2008 April. [Epub ahead of print].

  184. Pearson KJ, Lewis KN, Price NL, Chang JW, Perez E, Cascajo MV, Tamashiro KL, Poosala S, Csiszar A, Ungvari Z, Kensler TW, Yamamoto M, Egan JM, Longo DL, Ingram DK, Navas P, de Cabo R. Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci USA. 2008;105(7):2325-2330.

  185. Pilotto A, Ferrucci L, Franceschi M, D'Ambrosio LP, Scarcelli C, Cascavilla L, Paris F, Placentino G, Seripa D, Dallapiccola B, Leandro G. Development and validation of a multidimensional prognostic index for one-year mortality from comprehensive geriatric assessment in hospitalized older patients. Rejuvenation Res. 2008 Jan.; [Epub ahead of print].

  186. Pistell PJ, Zhu M, Ingram DK. Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease. Neuroscience. 2008;152(3):594-600.

  187. Qiu C, Cotch MF, Sigurdsson S, Garcia M, Klein R, Jonasson F, Klein BE, Eiriksdottir G, Harris TB, van Buchem MA, Gudnason V, Launer LJ. Retinal and cerebral microvascular signs and diabetes: the Age, Gene/Environment Susceptibility-Reykjavik Study. Diabetes. 2008 Mar.; [Epub ahead of print].

  188. Ravindran A, Lao QZ, Harry JB, Abrahimi P, Kobrinsky E, Soldatov NM. Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits. Proc Natl Acad Sci USA. 2008;105(23):8154-8159.

  189. Rao JS, Lee HJ, Rapoport SI, Bazinet RP. Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? Mol Psychiatry. 2008 Mar.; [Epub ahead of print].

  190. Rios E, Zhou J, Brum G, Launikonis BS, Stern MD. Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians. J Gen Physiol. 2008;131(4):335-348.

  191. Robinson VL, Shalhav O, Otto K, Kawai T, Gorospe M, Rinker-Schaeffer CW. Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines. Mol Cancer Res. 2008;6(3):501-508.

  192. Roth SM, Walsh S, Liu D, Metter EJ, Ferrucci L, Hurley BF. The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. Eur J Hum Genet. 2008;16(3):391-394.

  193. Rudow G, O’Brien R, Savonenko AV, Resnick SM, Zonderman AB, Pletnikova O, Marsh L, Dawson TM, Crain BJ, West MJ, Troncoso JC. Morphometry of the human substantia nigra in ageing and Parkinson’s disease. Acta Neuropathol. 2008 Feb.; [Epub ahead of print].

  194. Sahyoun NR, Anderson AL, Tylavsky FA, Lee JS, Sellmeyer DE, Harris TB; for the Health, Aging, and Body Composition Study. Dietary glycemic index and glycemic load and the risk of type 2 diabetes in older adults. Am J Clin Nutr. 2008;87(1):126-131.

  195. Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Scott LJ, Dei M, Lai S, Albai G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Ben-Shlomo Y, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, Smith GD, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet. 2008 Jan.; [Epub ahead of print].

  196. Schaap LA, Pluijm SM, Deeg DJ, Penninx BW, Nicklas BJ, Lips P, Harris TB, Newman AB, Kritchevsky SB, Cauley JA, Goodpaster BH, Tylavsky FA, Yaffe K, Visser M; for the Health ABC study. Low testosterone levels and decline in physical performance and muscle strength in older men: findings from two prospective cohort studies. Clin Endocrinol (Oxf). 2008;68(1):42-50.

  197. Schrager MA, Kelly VE, Price R, Ferrucci L, Shumway-Cook A. The effects of age on medio-lateral stability during normal and narrow base walking. Gait Posture. 2008 Apr.; [Epub ahead of print].

  198. Scola L, Lio D, Candore G, Forte GI, Crivello A, Colonna-Romano G, Pes MG, Carru C, Ferrucci L, Deiana L, Baggio G, Franceschi C, Caruso C. Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians. Exp Gerontol. 2008;43(2):114-118.

  199. Shafferman A, Barak D, Stein D, Kronman C, Velan B, Greig NH, Ordentlich A. Flexibility versus "rigidity" of the functional architecture of AChE active center. Chem Biol Interact. 2008 April. [Epub ahead of print].

  200. Sharma S, Brosh RM Jr. Unique and important consequences of RECQ1 deficiency in mammalian cells. Cell Cycle. 2008 Jan.;7(8) [Epub ahead of print].

  201. Sharma S, Sommers JA, Brosh RM Jr. Processing of DNA replication and repair intermediates by the concerted action of RecQ helicases and Rad2 structure-specific nucleases. Protein Pept Lett. 2008;15(1):89-102.

  202. Sharov AA, Falco G, Piao Y, Poosala S, Becker KG, Zonderman AB, Longo DL, Schlessinger D, Ko MS. Effects of aging and calorie restriction on the global gene expression profiles of testis and ovary. BMC Biol. 2008;6(1):24.

  203. Sharov AA, Masui S, Sharova LV, Piao Y, Aiba K, Matoba R, Xin L, Niwa H, Ko MS. Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data. BMC Genomics. 2008;9:269.

  204. Shin YK, Martin B, Golden E, Dotson CD, Maudsley S, Kim W, Jang HJ, Mattson MP, Drucker DJ, Egan JM, Munger SD. Modulation of taste sensitivity by GLP-1 signaling. J Neurochem. 2008 April; [Epub ahead of print].

  205. Shivakumar K, Sollott SJ, Sangeetha M, Sapna S, Ziman B, Wang S, Lakatta EG. Paracrine effects of hypoxic fibroblast-derived factors on the MPT-ROS threshold and viability of adult rat cardiac myocytes. Am J Physiol Heart Circ Physiol. 2008;294:H2653-H2658.

  206. Simon-Sanchez J, Scholz S, Matarin Mdel M, Fung HC, Hernandez D, Gibbs JR, Britton A, Hardy J, Singleton A. Genomewide SNP assay reveals mutations underlying Parkinson disease. Hum Mutat. 2008;29(2):315-322.

  207. Simon-Sanchez J, Singleton AB. Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls. Hum Mol Genet. 2008 Mar.; [Epub ahead of print].

  208. Singh UP, Singh S, Singh R, Cong Y, Taub DD, Lillard JW Jr. CXCL10-producing mucosal CD4+ T cells, NK cells, and NKT cells are associated with chronic colitis in IL-10(-/-) mice, which can be abrogated by anti-CXCL10 antibody inhibition. J Interferon Cytokine Res. 2008;28(1):31-43.

  209. Singh UP, Singh R, Singh S, Karls RK, Quinn FD, Taub DD, Lillard JW Jr. CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis. BMC Immunol. 2008;9(1):25.

  210. Son TG, Camandola S, Mattson MP. Hormetic dietary phytochemicals. Neuromolecular Med. 2008 June. [Epub ahead of print].

  211. Stein JH, Korcarz CE, Hurst RT, Lonn E, Kendall CB, Mohler ER, Najjar SS, Rembold CM, Post WS. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the american society of echocardiography carotid intima-media thickness task force endorsed by the society for vascular medicine. J Am Soc Echocardiogr. 2008;21(2):93-111.

  212. Stevens KN, Lang IA, Guralnik JM, Melzer D. Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of Ageing. Age Ageing. 2008.; [Epub ahead of print].

  213. Stevnsner T, Muftuoglu M, Aamann MD, Bohr VA. The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. Mech Ageing Dev. 2008;129(7-8):441-448.

  214. Stranahan AM, Arumugam TV, Cutler RG, Lee K, Egan JM, Mattson MP. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci. 2008;11(3):309-317.

  215. Stranahan AM, Lee K, Mattson MP. Central mechanisms of HPA axis regulation by voluntary exercise. Neuromolecular Med. 2008 Feb.; [Epub ahead of print].

  216. Stranahan AM, Lee K, Mattson MP. Contributions of impaired hippocampal plasticity and neurodegeneration to age-related deficits in hormonal pulsatility. Ageing Res Rev. 2008 Jan.; [Epub ahead of print].

  217. Stranahan AM, Mattson MP. Impact of energy intake and expenditure on neuronal plasticity. Neuromolecular Med. 2008 June. [Epub ahead of print].

  218. Strasak AM, Kelleher CC, Brant LJ, Rapp K, Ruttmann E, Concin H, Diem G, Pfeiffer KP, Ulmer H; VHM&PP Study Group. Serum uric acid is an independent predictor for all major forms of cardiovascular death in 28,613 elderly women: A prospective 21-year follow-up study. Int J Cardiol. 2008;125(2):232-239.

  219. Strasak AM, Rapp K, Brant LJ, Hilbe W, Gregory M, Oberaigner W, Ruttmann E, Concin H, Diem G, Pfeiffer KP, Ulmer H; and the VHM&PP Study Group. Association of gamma-glutamyltransferase and risk of cancer incidence in men: a prospective study. Cancer Res. 2008;68(10):3970-3977.

  220. Strotmeyer ES, de Rekeneire N, Schwartz AV, Faulkner KA, Resnick HE, Goodpaster BH, Shorr RI, Vinik AI, Harris TB, Newman AB; for the Health ABC Study. The relationship of reduced peripheral nerve function and diabetes to physical performance in older white and black adults: The Health, Aging and Body Composition Study. Diabetes Care. 2008 June. [Epub ahead of print].

  221. Sveinbjornsdottir S, Sigurdsson S, Aspelund T, Kjartansson O, Eiriksdottir G, Valtysdottir B, Lopez OL, van Buchem MA, Jonsson PV, Gudnason V, Launer LJ. Cerebral microbleeds in the population based AGES Reykjavik study: Prevalence and location. J Neurol Neurosurg Psychiatry. 2008 Feb.; [Epub ahead of print].

  222. Szekely CA, Green RC, Breitner JC, Ostbye T, Beiser AS, Corrada MM, Dodge HH, Ganguli M, Kawas CH, Kuller LH, Psaty BM, Resnick SM, Wolf PA, Zonderman AB, Welsh-Bohmer KA, Zandi PP. No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology. 2008;70(24):2291-2298.

  223. Taub DD. Novel connections between the neuroendocrine and immune systems: the ghrelin immunoregulatory network. Vitam Horm. 2008;77:325-346.

  224. Terracciano A, Lockenhoff CE, Crum RM, Bienvenu OJ, Costa PT Jr. Five-Factor Model personality profiles of drug users. BMC Psychiatry. 2008;8(1):22 [Epub ahead of print].

  225. Tetievsky A, Cohen O, Eli-Berchoer L, Gerstenblith G, Stern MD, Wapinski I, Friedman N, Horowitz M. Physiological and molecular evidence of heat acclimation memory: A lesson from thermal responses and ischemic cross-tolerance in the heart. Physiol Genomics. 2008 Apr.; [Epub ahead of print].

  226. Thorpe RJ Jr, Kasper JD, Szanton SL, Frick KD, Fried LP, Simonsick EM. Relationship of race and poverty to lower extremity function and decline: Findings from the Women's Health and Aging Study. Soc Sci Med. 2008;66(4):811-821.

  227. Toscano CD, Ueda Y, Tomita YA, Vicini S, Bosetti F. Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice. Brain Res Bull. 2008 ;75(5):598-609.

  228. Troncoso JC, Zonderman AB, Resnick SM, Crain B, Pletnikova O, O'Brien RJ. Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging. Ann Neurol. 2008 May. [Epub ahead of print].

  229. Trzeciak AR, Barnes J, Evans MK. A modified alkaline comet assay for measuring DNA repair capacity in human populations. Radiat Res. 2008;169(1):110-121.

  230. Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, Chen W, Usala G, Busonero F, Maschio A, Albai G, Piras MG, Sestu N, Lai S, Dei M, Mulas A, Crisponi L, Naitza S, Asunis I, Deiana M, Nagaraja R, Perseu L, Satta S, Cipollina MD, Sollaino C, Moi P, Hirschhorn JN, Orkin SH, Abecasis GR, Schlessinger D, Cao A. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci USA. 2008;105(5):1620-1625.

  231. Ungvari Z, Parrado-Fernandez C, Csiszar A, de Cabo R. Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res. 2008;102(5):519-528.

  232. Vidula H, Tian L, Liu K, Criqui MH, Ferrucci L, Pearce WH, Greenland P, Green D, Tan J, Garside DB, Guralnik J, Ridker PM, Rifai N, McDermott MM. Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study. Ann Intern Med. 2008;148(2):85-93.

  233. Vinogradova TM, Sirenko S, Lyashkov AE, Younes A, Li Y, Zhu W, Yang D, Ruknudin AM, Spurgeon H, Lakatta EG. Constitutive phosphodiesterase activity restricts spontaneous beating rate of cardiac pacemaker cells by suppressing local Ca2+ releases. Circ Res. 2008;102:761-769.

  234. Volpato S, Ble A, Metter EJ, Lauretani F, Bandinelli S, Zuliani G, Fellin R, Ferrucci L, Guralnik JM. High-density lipoprotein cholesterol and objective measures of lower extremity performance in older nondisabled persons: The InChianti Study. J Am Geriatr Soc. 2008;56(4):621-629.

  235. Waldstein SR, Rice SC, Thayer JF, Najjar SS, Scuteri A, Zonderman AB. Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging. Hypertension. 2008;51(1):99-104.

  236. Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM, Nord AS, Kusenda M, Malhotra D, Bhandari A, Stray SM, Rippey CF, Roccanova P, Makarov V, Lakshmi B, Findling RL, Sikich L, Stromberg T, Merriman B, Gogtay N, Butler P, Eckstrand K, Noory L, Gochman P, Long R, Chen Z, Davis S, Baker C, Eichler EE, Meltzer PS, Nelson SF, Singleton AB, Lee MK, Rapoport JL, King MC, Sebat J. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science. 2008 Mar.; [Epub ahead of print].

  237. Wang L, Shim H, Xie C, Cai H. Activation of protein kinase C modulates BACE1-mediated beta-secretase activity. Neurobiol Aging. 2008;29(3):357-367.

  238. Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, Cai H. The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2. J Neurosci. 2008;28(13):3384-3391.

  239. Wang Y, Chandran JS, Cai H, Mattson MP. DJ-1 is essential for long-term depression at hippocampal CA1 synapses. Neuromolecular Med. 2008 Feb 2; [Epub ahead of print].

  240. Webster JA, Myers AJ, Pearson JV, Craig DW, Hu-Lince D, Coon KD, Zismann VL, Beach T, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Huentelman MJ, Joshipura K, Walker D, Heward CB, Ravid R, Rogers J, Papassotiropoulos A, Hardy J, Reiman EM, Stephan DA. Sorl1 as an Alzheimer's disease predisposition gene? Neurodegener Dis. 2008;5(2):60-64.

  241. Weissman L, de Souza-Pinto NC, Mattson MP, Bohr VA. DNA base excision repair activities in mouse models of Alzheimer's disease. Neurobiol Aging. 2008 Mar.; [Epub ahead of print].

  242. Weng NP. Telomere and adaptive immunity. Mech Ageing Dev. 2008;129(1-2):60-66.

  243. Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, Albai G, Swift AJ, Morken MA, Narisu N, Bennett D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen WM, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R, Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet. 2008;40:161-169.

  244. Wilson DM 3rd, Bohr VA, McKinnon PJ. DNA damage, DNA repair, aging and age-related disease. Mech Ageing Dev. 2008 March; [Epub ahead of print].

  245. Wilson DR, Norton DD, Fugmann SD. The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails. Dev Comp Immunol. 2008 May. [Epub ahead of print].

  246. Woo AY, Waye MM, Tsui SK, Yeung ST, Cheng CH. Andrographolide up-regulates cellular-reduced glutathione level and protects cardiomyocytes against hypoxia/reoxygenation injury. J Pharmacol Exp Ther. 2008;325(1):226-235.

  247. Wu J, Cho HP, Rhee DB, Johnson DK, Dunlap J, Liu Y, Wang Y. Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication. J Cell Biol. 2008;181(3):475-483.

  248. Wu Y, Rawtani N, Thazhathveetil AK, Kenny MK, Seidman MM, Brosh RM Jr. Human replication protein A melts a DNA triple helix structure in a potent and specific manner. Biochemistry. 2008 Apr.; [Epub ahead of print].

  249. Wu Y, Shin-Ya K, Brosh RM Jr. FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. Mol Cell Biol. 2008 Apr.; [Epub ahead of print].

  250. Xiong C, Tang Y, van Belle G, Miller JP, Launer LJ, Morris JC. Evaluating the quality of longitudinal statistical applications in original publications on Alzheimer's disease. Neuroepidemiology. 2008;30(2):112-119.

  251. Xiromerisiou G, Hadjigeorgiou GM, Papadimitriou A, Katsarogiannis E, Gourbali V, Singleton AB. Association between AKT1 gene and Parkinson's disease: A protective haplotype. Neurosci Lett. 2008;436(2):232-234.

  252. Xu M, Yu Q, Subrahmanyam R, Difilippantonio MJ, Ried T, Sen JM. Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo. Mol Cell Biol. 2008;28(5):1713-1723.

  253. Xue Y, Li Y, Guo R, Ling C, Wang W. FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair. Hum Mol Genet. 2008 Feb.; [Epub ahead of print].

  254. Yaffe K, Lindquist K, Shlipak MG, Simonsick E, Fried L, Rosano C, Satterfield S, Atkinson H, Windham BG, Kurella-Tamura M; Health ABC Study. Cystatin C as a marker of cognitive function in elders: Findings from the Health ABC Study. Ann Neurol. 2008 May. [Epub ahead of print].

  255. Yamada Y, Tian J, Yang Y, Cutler RG, Wu T, Telljohann RS, Mattson MP, Handa JT. Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells. J Neurochem. 2008 Jan.; [Epub ahead of print].

  256. Yamanaka S, Li J, Kania G, Elliott S, Wersto RP, Van Eyk J, Wobus AM, Boheler KR. Pluripotency of embryonic stem cells. Cell Tissue Res. 2008;331(1):5-22.

  257. Yan Z, Wang Z, Sharova L, Sharov AA, Ling C, Piao Y, Aiba K, Matoba R, Wang W, Ko MS. BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells. Stem Cells. 2008 Mar.; [Epub ahead of print].

  258. Yang JL, Weissman L, Bohr VA, Mattson MP. Mitochondrial DNA damage and repair in neurodegenerative disorders. DNA Repair (Amst). 2008 May. [Epub ahead of print].

  259. Yang Y, An J, Weng NP. Telomerase is involved in IL-7-mediated differential survival of naive and memory CD4+ T cells. J Immunol. 2008;180(6):3775-3781.

  260. You T, Nicklas BJ, Ding J, Penninx BW, Goodpaster BH, Bauer DC, Tylavsky FA, Harris TB, Kritchevsky SB. The metabolic syndrome is associated with circulating adipokines in older adults across a wide range of adiposity. J Gerontol A Biol Sci Med Sci. 2008;63(4):414-419.

  261. Younes A, Lyashkov AE, Graham D, Sheydina A, Volkova MV, Mitsak M, Vinogradova TM, Lukyanenko YO, Li Y, Ruknudin AM, Boheler KR, van Eyk J, Lakatta EG. Ca2+-stimulated basal adenylyl cyclase activity localization in membrane lipid microdomains of cardiac sinoatrial nodal pacemaker cells. J Biol Chem. 2008;283(21):14461-14468.

  262. Zhan M. Genomic studies to explore self-renewal and differentiation properties of embryonic stem cells. Front Biosci. 2008;13:276-283.

  263. Zhang W, Zou S, Song J. Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in drosophila melanogaster. BMC Bioinformatics. 2008;9(1):129.

  264. Zou T, Liu L, Rao JN, Marasa BS, Chen J, Xiao L, Zhou H, Gorospe M, Wang JY. Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1. Biochem J. 2008;409(2):389-398.

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