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Susan M. Resnick, Ph.D. Susan M. Resnick, Ph.D., Senior Investigator
Cognition Section
Laboratory of Personality and Cognition

E-mail: resnicks@grc.nia.nih.gov

Education:

1972 - Graduated high school
1976 - B.S., Tufts University, Psychology, magna cum laude
1983 - Ph.D., University of Minnesota, Differential Psychology/Behavioral Genetics; Major: Psychology; Minor: Genetics
1984 - Postdoctoral Fellowship, University of Pennsylvania

Licensure:

1986 - Licensed Psychologist, Commonwealth of Pennsylvania

Brief Chronology of Employment:

1976-79 - Teaching Assistant, Department of Psychology, University of Minnesota

1978-82 - NIMH Predoctoral Trainee in Behavioral Genetics, Dight Institute for Human Genetics University of Minnesota

1979 - Research Assistant, Study of Identical Twins Reared Apart, University of Minnesota

1981 - Clerkship in Neuropsychology, University Hospitals, University of Minnesota

1980-81 - Instructor, Department of Psychology, University of Minnesota, Courses: Behavioral Genetics, Differential Psychology

1982-84 - NIMH Postdoctoral Trainee in Neuropsychology and Neuroimaging, University of Pennsylvania

1984-86 - Research Associate, Department of Psychiatry, University of Pennsylvania

1986-92 - Research Assistant Professor of Psychology in Psychiatry, Department of Psychiatry, University of Pennsylvania

1992-2004 - Senior Staff Fellow, Laboratory of Personality and Cognition, National Institute on Aging

2004-present - Senior Investigator, Laboratory of Personality and Cognition, National Institute on Aging

Societies:

American Association for the Advancement of Science

Behavior Genetics Association, 1977
Associate Member-at-Large, 1980-1982
Membership Committee, 1995-1997
American Psychological Society, 1994
International Neuropsychological Society, 1985-1989

Honors and Other Special Scientific Recognition:

University of Minnesota Dissertation Research Grant, 1979

Other Academic Activities:

Ad hoc reviewer: American Journal of Psychiatry, Behavior Genetics, Biological Psychiatry, Developmental Neuropsychology, Journal of Abnormal Psychology, Journal of Nervous and Mental Diseases, Neuropsychologia, Psychiatry Research, Schizophrenia Bulletin, Science

Principal Investigator of Grants: University of Pennsylvania
The Application of Genetic Strategies to Neuroimaging Studies of Schizophrenia, FIRST Award MH43740-01, September 30, 1987 to August 31, 1992.
Genetics Core, Mental Health Clinical Research Center (RE Gur, MHCRC PI), August 1988 to June 1992.
Image Analysis Core, co-PI, PET Center in Psychiatry (RE Gur, PET Psychiatry Center PI), September, 1991 to June 1992.
Late Onset Depression and Alzheimer's Disease: Genetic Factors, Pilot Project PI, Alzheimer's Disease Center Core (John Trojanowski, Center PI), October 1991 to September 1996, transferred to Dr. Jennifer Lish due to acceptance of intramural position.

Bibliography:

  1. Resnick S, Gottesman II. Prenatal hormones and IQ: need for sibling controls. Brit J Psychiatry. 1978;131:204-205.

  2. Bouchard TJ, Heston LL, Eckert ED, Keyes M, Resnick S. The Minnesota study of twins reared apart: project description and sample results in the developmental domain. Prog Clin Bio Res. 1981;69B:227-233.

  3. Berenbaum SA, Resnick S. Somatic androgyny and cognitive abilities. Dev Psychol. 1982;18:418-423. Abstract

  4. Gur RE, Gur RC, Skolnick BE, Caroff S, Obrist WD, Resnick S, Reivich M. Brain function in psychiatric disorders. III. Regional cerebral blood flow in unmedicated schizophrenics. Arch Gen Psychiatry. 1985;42:329-334. Abstract

  5. Resnick SM, Berenbaum SA, Gottesman II, Bouchard TJ. Early hormonal influences on cognitive functioning in congenital adrenal hyperplasia. Dev Psychol. 1986;22:191-198. Abstract

  6. Gur RC, Gur RE, Resnick SM, Skolnick BE, Alavi A, Reivich M. The effect of anxiety on cortical cerebral blood flow and metabolism. J Cereb Blood Flow Metab. 1987;7:173-177. Abstract

  7. Gur RE, Resnick SM, Alavi A, Gur RC, Caroff S, Dann R, Silver FL, Saykin AJ, Chawluk JB, Kushner M, et al. Regional brain function in schizophrenia. I. A positron emission tomography study. Arch Gen Psychiatry. 1987;44:119-125. Abstract

  8. Gur RE, Resnick SM, Gur RC, Alavi A, Caroff S, Kushner M, Reivich M. Regional brain function in schizophrenia. II. Repeated evaluation with positron emission tomography. Arch Gen Psychiatry. 1987;44:126-129. Abstract

  9. Gur RC, Gur RE, Skolnick BE, Resnick SM, Silver FL, Chawluk J, Muenz L, Obrist WD, Reivich M. Effects of task difficulty on regional cerebral blood flow: relationships with anxiety and performance. Psychophysiology. 1988;25:392-399.

  10. Resnick SM, Gottlieb GL, Gur RE, Gur RC, et al. Identical twins with probable Alzheimer's disease: Behavior, anatomy, and physiology. Neuropsychiatry Neuropsychol Behav Neurol. 1988;1:61-72. Abstract

  11. Resnick SM, Gur RE, Alavi A, Gur RC, Reivich M. Positron emission tomography and subcortical glucose metabolism in schizophrenia. Psychiatry Res. 1988;24:1-11. Abstract

  12. Gur RE, Resnick SM, Gur RC. Laterality and frontality of cerebral blood flow and metabolism in schizophrenia: relationship to symptom specificity. Psychiatry Res. 1989;27:325-334. Abstract

  13. Chawluk JB, Dann R, Alavi A, Hurtig HI, Gur RE, Resnick S, Zimmerman RA, Reivich M. The effect of focal cerebral atrophy in positron emission tomographic studies of aging and dementia. Int J Rad Appl Instrum [B]. 1990;17:797-804.

  14. Sperling MR, Gur RC, Alavi A, Gur RE, Resnick S, O'Connor MJ, Reivich M. Subcortical metabolic alterations in partial epilepsy. Epilepsia. 1990;31:145-55.

  15. Erwin RJ, Resnick SM, Mawinney-Hee M, Mozley D, Gur RC, Gur RE. Midlatency auditory evoked responses and neuroimaging in schizophrenia. Bio Basis Schiz. 1991:43-53.

  16. Gur RC, Mozley PD, Resnick SM, Gottlieb GL, Kohn M, Zimmerman R, Herman G, Atlas S, Grossman R, Berretta D, Erwin R, Gur RE. Gender differences in age effect on brain atrophy measured by magnetic resonance imaging. Proc Natl Acad Sci.. 1991;88:2845-2849. Abstract

  17. Gur RE, Mozley PD, Resnick SM, Levick S, Erwin R, Saykin AJ, Gur RC. Relations among clinical scales in schizophrenia. A J Psych. 1991;148:472-478. Abstract

  18. Gur RE, Mozley PD, Resnick SM, Shtasel D, Kohn M, Zimmerman R, Herman G, Atlas S, Grossman R, Erwin R, et al. Magnetic resonance imaging in schizophrenia. I. Volumetric analysis of brain and cerebrospinal fluid. Arch Gen Psychiatry. 1991;48:407-412. Abstract

  19. Kohn MI, Tanna NK, Herman GT, Resnick SM, Mozley PD, Gur RE, Alavi A, Zimmerman RA, Gur RC. Analysis of brain and cerebrospinal fluid volumes with MR imaging. Part I. Methods, reliability, and validation. Radiology. 1991;178:115-22. Abstract

  20. Saykin AJ, Gur RC, Gur RE, Mozley PD, Mozley LH, Resnick SM, Kester DB, Stafiniak P. Neuropsychological function in schizophrenia. Selective impairment in memory and learning. Arch Gen Psychiatry. 1991;48:618-624. Abstract

  21. Resnick SM. Positron emission tomography in psychiatric illness. Current Directions in Psychological Science. 1992;1:92-98.

  22. Resnick SM. Matching for education in studies of schizophrenia. Arch Gen Psychiatry. 1992;49:246. Abstract

  23. Gur RC, Jaggi JL, Ragland JD, Resnick SM, Shtasel D, Muenz L, Gur RE. Effects of memory processing on regional brain activation: cerebral blood flow in normal subjects. Int J Neurosci. 1993;72:31-44. Abstract

  24. Lish JD, Gyulai L, Resnick SM, Kirtland A, Amsterdam JD, Whybrow PC, Price RA. A family history study of rapid-cycling bipolar disorder. Psych Res. 1993;48:37-46. Abstract

  25. Resnick SM. Sex differences in mental rotations: an effect of time limits? Brain Cogn. 1993;21:71-79. Abstract

  26. Resnick SM, Gottesman II, McGue M. Sensation seeking in opposite-sex twins: An effect of prenatal hormones? Behav Genet. 1993;23:323-329. Abstract

  27. Resnick SM, Karp JS, Turetsky B, Gur RE. Comparison of anatomically-defined versus physiologically-based regional localization: effects on PET-FDG quantitation [Erratum in J Nucl Med 1994 Jan;35(1):26]. J Nucl Med. 1993;34:2201-2207. Abstract

  28. Gur RC, Ragland JD, Resnick SM, Skolnick BE, Jaggi J, Muenz L, Gur RE. Lateralized increases in cerebral blood flow during performance of verbal and spatial tasks: relationship with performance level. Brain Cogn. 1994;24:244-258. Abstract

  29. Mozley PD, Gur RE, Resnick SM, Shtasel DL, Richards J, Kohn M, Grossman R, Herman G, Gur RC. Magnetic resonance imaging in schizophrenia: relationship with clinical measures. Schizophr Res. 1994;12:195-203. Abstract

  30. Resnick SM, Lazar J, Gur RE, Gur RC. The stability of tachistoscopic measures of hemispheric specialization. Neuropsychologia. 1994;32:1419-1430. Abstract

  31. Resnick SM, Zonderman AB, Golski S, Metter EJ, Bryan RN, Costa PT. Memory change as a predictor of regional brain structure and function. Biomed Gerontol. 1994;18:206-210.

  32. Gur RC, Mozley LH, Mozley PD, Resnick SM, Karp JS, Alavi A, Arnold SE, Gur RE. Sex differences in regional cerebral glucose metabolism during a resting state. Science. 1995;267:528-531. Abstract

  33. Gur RE, Mozley PD, Resnick SM, Mozley LH, Shtasel DL, Gallacher F, Arnold SE, Karp JS, Alavi A, Reivich M, Gur RC. Resting cerebral glucose metabolism in first-episode and previously treated patients with schizophrenia relates to clinical features. Arch Gen Psychiatry. 1995;52:657-667. Abstract

  34. Liu X, Phillips RL, Resnick SM, Villemagne VL, Wong DF, Stapleton JM, London ED. Magnetic resonance imaging reveals no ventriculomegaly in polydrug abusers. Acta Neurologica Scandanavia. 1995;92:83-90. Abstract

  35. Resnick SM, Costa PT. Comments on use of H-1 MR spectroscopy for diagnosis of probable Alzheimer disease. Radiology. 1995;195:14-15. Abstract

  36. Resnick SM, Trotman KM, Kawas C, Zonderman AB. Age-associated changes in specific errors on the Benton Visual Retention Test. J Gerontol B Psychol Sci Soc Sci. 1995;50:P171-P178. Abstract

  37. Zonderman AB, Giambra LM, Arenberg D, Resnick SM, Costa PT. Changes in immediate visual memory predict cognitive impairment. Archiv Clin Neuropsychol. 1995;10:111-123. Abstract

  38. Davatzikos C, Vaillant M, Resnick SM, Prince JL, Letovsky S, Bryan RN. A computerized approach for morphological analysis of the corpus callosum. J Comp Assist Tomog. 1996;20:88-97. Abstract

  39. Wong DF, Resnick SM. Neuroreceptor imaging in neuropsychiatric disorders. In: Wagner HN, Jr, Szabo Z, eds. Principles of Nuclear Medicine, 2nd Edition; 1996.

  40. Kawas CH, Resnick S, Morrison A, Brookmeyer R, Corrada M, Zonderman AB, Baccall C, Lingle D, Metter E. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging. Neurology. 1997;48:1517-1521. Abstract

  41. Resnick SM, Metter EJ, Zonderman AB. Estrogen replacement therapy and longitudinal decline in visual memory: A possible protective effect? Neurology. 1997;49:1491-1497. Abstract

  42. Goldszal AF, Davatzikos C, Pham DL, Yan MX, Bryan RN, Resnick SM. An image-processing system for qualitative and quantitative volumetric analysis of brain images. J Comput Assist Tomogr. 1998; 22:827-837. Abstract

  43. Golski S, Zonderman AB, Malamut BL, Resnick SM. Verbal and figural recognition memory: Task development and age associations. Exp Aging Res. 1998;24:359-385. Abstract

  44. Rasmusson DX, Zonderman AB, Kawas CH, Resnick SM. Effects of age and dementia on the Trail Making Test. The Clinical Neuropsychologist. 1998;2:169-178. Abstract

  45. Resnick SM, Maki P, Golski S, Kraut M, Zonderman AB. Effects of estrogen replacement therapy on PET-CBF and neuropsychological performance. Horm Behav. 1998;34:171-182. Abstract

  46. Maki PM, Resnick SM. Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition. Neurobiol Aging. 2000;21:373-383. Abstract

  47. Resnick SM, Goldszal AF, Davatzikos C, Golski S, Kraut MA, Metter EJ, Bryan RN, Zonderman AB. One-year age changes in MRI brain volumes in older adults. Cereb Cortex 2000;10:464-472. Abstract

  48. Moffat SD, Szekely CA, Zonderman AB, Kabani NJ, Resnick SM. Longitudinal change in hippocampal volume as a function of apolipoprotein E genotype. Neurology. 2000;55(1):134-136. Abstract

  49. Moffat SD, Zonderman AB, Harman SM, Blackman MR, Resnick SM. The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older men. Arch. Intern. Med. 2000;160(14):2193-2198. Abstract

  50. Davatzikos C, Li HH, Herskovits E, Resnick SM. Accuracy and sensitivity of detection of activation foci in the brain via statistical parametric mapping: a study using a PET simulator. Neuroimage. 2001;13(1):176-184. Abstract

  51. Maki PM, Resnick SM. Effects of estrogen on patterns of brain activity at rest and during cognitive activity: a review of neuroimaging studies. Neuroimage. 2001;14(4):789-801. Abstract

  52. Moffat SD, Zonderman AB, Resnick SM. Age differences in spatial memory in a virtual environment navigation task. Neurobiol Aging. 2001;22(5):787-796. Abstract

  53. Davatzikos C, Genc A, Xu D, Resnick SM. Voxel-based morphometry using the RAVENS maps: methods and validation using simulated longitudinal atrophy. Neuroimage. 2001;14(6):1361-1369. Abstract

  54. Shen D, Moffat S, Resnick SM, Davatzikos C. Measuring size and shape of the hippocampus in MR images using a deformable shape model. Neuroimage. 2002;15(2):422-434. Abstract

  55. Resnick SM, Maki PM. Effects of hormone replacement therapy on cognitive and brain aging. Ann NY Acad Sci. 2001;949:203-214. Abstract

  56. Davatzikos C, Resnick SM. Degenerative age changes in white matter connectivity visualized in vivo using magnetic resonance imaging. Cereb Cortex. 2002;12(7):767-771. Abstract

  57. Moffat SD, Resnick SM. Effects of age on virtual environment place navigation and allocentric cognitive mapping. Behav Neurosci. 2002;116(5):851-859. Abstract

  58. Moffat SD, Zonderman AB, Metter EJ, Blackman MR, Harman SM, Resnick SM. Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. J Clin Endocrinol Metab. 2002;87(11):5001-5007. Abstract

  59. Resnick SM, Henderson VW. Hormone therapy and risk of Alzheimer disease: a critical time. JAMA. 2002;288(17):2170-2172.

  60. Lamar M, Resnick SM, Zonderman AB. Longitudinal changes in verbal memory in older adults: distinguishing the effects of age from repeat testing. Neurology. 2003;60(1):82-86. Abstract

  61. Kawas CH, Corrada MM, Brookmeyer R, Morrison A, Resnick SM, Zonderman AB, Arenberg D. Visual memory predicts Alzheimer's disease more than a decade before diagnosis. Neurology. 2003;60(7):1089-1093. Abstract

  62. Resnick SM, Pham DL, Kraut MA, Zonderman AB, Davatzikos C. Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain. J Neurosci. 2003;23(8):3295-3301. Abstract

  63. Lao Z, Shen D, Xue Z, Karacali B, Resnick SM, Davatzikos C. Morphological classification of brains via high-dimensional shape transformations and machine learning methods. Neuroimage. 2004;21(1):46-57. Abstract

  64. Moffat SD, Zonderman AB, Metter EJ, Kawas C, Blackman MR, Harman SM, Resnick SM. Free testosterone and risk for Alzheimer disease in older men. Neurology. 2004;62(2):188-193. Abstract

  65. Lamar M, Resnick SM. Aging and prefrontal functions: dissociating orbitofrontal and dorsolateral abilities. Neurobiol Aging. 2004;25(4):553-558. Abstract

  66. Lamar M, Yousem DM, Resnick SM. Age differences in orbitofrontal activation: an fMRI investigation of delayed match and nonmatch to sample. Neuroimage. 2004;21(4):1368-1376. Abstract

  67. Berenbaum SA, Korman Bryk K, Duck SC, Resnick SM. Psychological adjustment in children and adults with congenital adrenal hyperplasia. J Pediatr. 2004;144(6):741-746. Abstract

  68. Tosun D, Rettmann ME, Han X, Tao X, Xu C, Resnick SM, Pham DL, Prince JL. Cortical surface segmentation and mapping. Neuroimage. 2004;23 Suppl 1:S108-S118. Abstract

  69. Resnick SM, Coker LH, Makia PM, Rapp SR, Espeland MA, Shumaker SA. The Women's Health Initiative Study of Cognitive Aging (WHISCA): a randomized clinical trial of the effects of hormone therapy on age-associated cognitive decline. Clin Trials. 2004;1(5):440-450. Abstract

  70. Beason-Held LL, Golski S, Kraut MA, Esposito G, Resnick SM. Brain activation during encoding and recognition of verbal and figural information in older adults. Neurobiol Aging. 2005;26(2):237-250. Abstract

  71. Rettmann ME, Tosun D, Tao X, Resnick SM, Prince JL. Program for Assisted Labeling of Sulcal Regions (PALS): description and reliability. Neuroimage. 2005;24(2):398-416. Abstract

  72. Mikolaenko I, Pletnikova O, Kawas CH, O'Brien R, Resnick SM, Crain B, Troncoso JC. Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA). J Neuropathol Exp Neurol. 2005;64(2):156-162. Abstract

  73. Moffat SD, Elkins W, Resnick SM. Age differences in the neural systems supporting human allocentric spatial navigation. Neurobiol Aging. 2005; [Epub ahead of print]. Abstract

  74. Tosun D, Rettmann ME, Naiman DQ, Resnick SM, Kraut MA, Prince JL. Cortical reconstruction using implicit surface evolution: Accuracy and precision analysis. Neuroimage. 2006;29(3):838-852. Abstract

  75. Rettmann ME, Kraut MA, Prince JL, Resnick SM. Cross-sectional and longitudinal analyses of anatomical sulcal changes associated with aging. Cereb. Cortex. 2005 Dec.; [Epub ahead of print]. Abstract

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