Busch CM, Zonderman AB, Costa PT, Jr. Menopausal transition and psychological distress in a nationally representative sample: Is menopause associated with psychological distress? Journal of Aging and Health 1994;6(2):209-228.

Examined whether menopause is associated with 3 measures of psychological distress: depression, well-being, and sleep disturbance. Women aged 40-60 yrs from the National Health Examination Follow-up Study (National Center for Health Statistics, 1973, 1978) were assigned to groups based on their menopause status: premenopause ( n = 989), perimenopause ( n = 312), natural menopause ( n = 781), and surgical menopause ( n = 967). Over a 10-yr follow-up interval, no increase was found in depression, in poor psychological well being, or in sleep disturbance associated with the menopause transition. The only longitudinal change was a slight decline in depression over time for all groups. Psychological distress was unrelated to the number of years since menopause and the timing of menopausal transition.