National Institute on Aging
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Research Programs
Intramural
Laboratory of Immunology
Publications

  1. Anderson DE, Fedorova OV, Morrell CH, Longo DL, Kashkin VA, Metzler JD, Bagrov AY, Lakatta EG. Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives. Am J Physiol Regul Integr Comp Physiol. 2008;294(4):R1248-R1254.

  2. Araki Y, Fann M, Wersto R, Weng NP. Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (Eomesodermin and its targets: Perforin and Granzyme B). J Immunol. 2008;180(12):8102-8108.

  3. Biragyn A, Coscia M, Nagashima K, Sanford M, Young HA, Olkhanud P. Murine {beta}-defensin 2 promotes TLR-4/MyD88-mediated and NF-{kappa}B-dependent atypical death of APCs via activation of TNFR2. J Leukoc Biol. 2008;83(4):998-1008.

  4. Dawson HD, Collins G, Pyle R, Key M, Taub DD. Retinoic acid receptor-alpha mediates human T-cell activation and Th2 cytokine production. BMC Immunol. 2008;9(1):16.

  5. Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT. Wnt5A regulates expression of tumor associated antigens in melanoma via changes in STAT3 phosphorylation. Cancer Res. 2008;68(24):10205-10214.

  6. Earley CJ, Ponnuru P, Wang X, Patton SM, Conner JR, Beard JL, Taub DD, Allen RP. Altered iron metabolism in lymphocytes from subjects with restless legs syndrome. Sleep. 2008;31(6):847-852.

  7. Fedorova OV, Simbirtsev AS, Kolodkin NI, Kotov AY, Agalakova NI, Kashkin VA, Tapilskaya NI, Bzhelyansky A, Reznik VA, Frolova EV, Nikitina ER, Budny GV, Longo DL, Lakatta EG, Bagrov AY. Monoclonal antibody to an endogenous bufadienolide, marinobufagenin, reverses preeclampsia-induced Na/K-ATPase inhibition and lowers blood pressure in NaCl-sensitive hypertension. J Hypertens. 2008;26(12):2414-2425.

  8. Ghosh MC, Baatar D, Collins G, Carter A, Indig F, Biragyn A, Taub DD. Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck. Blood. 2008 Oct. [Epub ahead of print].

  9. Heltemes-Harris LM, Gearhart PJ, Ghosh P, Longo DL. Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion. Mol Immunol. 2008;45(6):1799-1806.

  10. Hossain MZ, Yu Q, Xu M, Sen JM. ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells. Int Immunol. 2008;20(7):925-935.

  11. Huang MC, Liao JJ, Bonasera S, Longo DL, Goetzl EJ. Nuclear factor-{kappa}B-dependent reversal of aging-induced alterations in T cell cytokines. FASEB J. 2008;22(7):2142-2150.

  12. Kamperschroer C, Roberts DM, Zhang Y, Weng NP, Swain SL. SAP Enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation. J Immunol. 2008;181(6):3994-4003.

  13. Ko MSH. Stem Cell Biology, Chapter 66, Harrison's Principles of Internal Medicine, 17th Edition, 2008. (Eds. Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J). McGraw-Hill, NY.

  14. Ling SM, Patel DD, Garnero P, Zhan M, Vaduganathan M, Muller D, Taub D, Bathon JM, Hochberg M, Abernethy DR, Metter EJ, Ferrucci L. Serum protein signatures detect early radiographic osteoarthritis. Osteoarthritis Cartilage. 2008;17(1):43-48.

  15. Movsesyan N, Ghochikyan A, Mkrtichyan M, Petrushina I, Davtyan H, Olkhanud PB, Head E, Biragyn A, Cribbs DH, Agadjanyan MG. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS ONE. 2008;3(5):e2124.

  16. Pearson KJ, Lewis KN, Price NL, Chang JW, Perez E, Cascajo MV, Tamashiro KL, Poosala S, Csiszar A, Ungvari Z, Kensler TW, Yamamoto M, Egan JM, Longo DL, Ingram DK, Navas P, de Cabo R. Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci USA. 2008;105(7):2325-2330.

  17. Ruggiero C, Metter EJ, Melenovsky V, Cherubini A, Najjar SS, Ble A, Senin U, Longo DL, Ferrucci L. High basal metabolic rate is a risk factor for mortality: the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci. 2008;63(7):698-706.

  18. Sakthivel SK, Singh UP, Singh S, Taub DD, Igietseme JU, Lillard JW Jr. CCL5 regulation of mucosal chlamydial immunity and infection. BMC Microbiol. 2008; 8(1):136.

  19. Sakthivel SK, Singh UP, Singh S, Taub DD, Novakovic KR, Lillard JW Jr. CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. J Immune Based Ther Vaccines. 2008;6:6.

  20. Semba RD, Patel KV, Sun K, Guralnik JM, Ershler WB, Longo DL, Ferrucci L. Association between serum carboxymethyl-lysine, a dominant advanced glycation end product, and anemia in adults: the Baltimore Longitudinal Study of Aging. J Am Geriatr Soc. 2008;56(11):2145-2147.

  21. Sharov AA, Falco G, Piao Y, Poosala S, Becker KG, Zonderman AB, Longo DL, Schlessinger D, Ko MS. Effects of aging and calorie restriction on the global gene expression profiles of testis and ovary. BMC Biol. 2008;6(1):24.

  22. Singh UP, Singh S, Singh R, Cong Y, Taub DD, Lillard JW Jr. CXCL10-producing mucosal CD4+ T cells, NK cells, and NKT cells are associated with chronic colitis in IL-10(-/-) mice, which can be abrogated by anti-CXCL10 antibody inhibition. J Interferon Cytokine Res. 2008;28(1):31-43.

  23. Singh UP, Singh R, Singh S, Karls RK, Quinn FD, Taub DD, Lillard JW Jr. CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis. BMC Immunol. 2008;9(1):25.

  24. Staal FJ, Sen JM. The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis. Eur J Immunol. 2008;38(7):1788-1794.

  25. Taub DD. Novel connections between the neuroendocrine and immune systems: the ghrelin immunoregulatory network. Vitam Horm. 2008;77:325-346.

  26. Taub DD, Ershler WB, Janowski M, Artz A, Key ML, McKelvey J, Muller D, Moss B, Ferrucci L, Duffey PL, Longo DL. Immunity from smallpox vaccine persists for decades: a longitudinal study. Am J Med. 2008;121(12):1058-1064.

  27. Weng NP. Telomere and adaptive immunity. Mech Ageing Dev. 2008;129(1-2):60-66.

  28. Xu M, Yu Q, Subrahmanyam R, Difilippantonio MJ, Ried T, Sen JM. Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo. Mol Cell Biol. 2008;28(5):1713-1723.

  29. Yang H, Dixit VD, Patel K, Vandanmagsar B, Collins G, Sun Y, Smith RG, Taub DD. Reduction in hypophyseal growth hormone and prolactin expression due to deficiency in ghrelin receptor signaling is associated with Pit-1 suppression: Relevance to the immune system. Brain Behav Immun. 2008 June. [Epub ahead of print].

  30. Yang Y, An J, Weng NP. Telomerase is involved in IL-7-mediated differential survival of naive and memory CD4+ T cells. J Immunol. 2008;180(6):3775-3781.

  31. Yu Q, Quinn WJ 3rd, Salay T, Crowley JE, Cancro MP, Sen JM. Role of {beta}-catenin in B cell development and function. J Immunol. 2008;181(6):3777-3783.

  32. Baatar D, Olkhanud P, Newton D, Sumitomo K, Biragyn A. CCR4-expressing T cell tumors can be specifically controlled via delivery of toxins to chemokine receptors. J. Immunol. 179(3):1996-2004, 2007.

  33. Baatar D, Olkhanud P, Sumitomo K, Taub D, Gress R, Biragyn A. Human peripheral blood T regulatory cells (Tregs), functionally primed CCR4+ Tregs and unprimed CCR4- Tregs, regulate effector T cells using FasL. J. Immunol. 178(8):4891-4900, 2007.

  34. Berner, V., Liu, H., Zhou, Q., Alderson, K.L., Sun, K., Weiss, J.M., Back, T.C., Longo, D.L., Blazar, B.R., Wiltrout, R.H., Welniak, L.A., Redelman, D., Murphy, W.J.: IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy. Nat. Med. 13(3):354-360, 2007.

  35. Biragyn A, Schiavo R, Olkhanud P, Sumitomo K, King A, McCain M, Indig FE, Almanzar G, Baatar D. Tumor-associated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity. J. Immunol. 179(2):1381-1388, 2007.

  36. Brodsky, M., Yosef, S., Galit, R., Albeck, M., Longo, D.L., Albeck, A., Sredni, B.: The synthetic tellurium compound, AS101, is a novel inhibitor of IL-1beta converting enzyme. J. Interferon Cytokine Res. 27(6):453-462, 2007.

  37. Chen, G., Ghosh, P., Osawa, H., Sasaki, C.Y., Rezanka, L., Yang, J., O'Farrell, T.J., Longo, D.L.: Resistance to TGF-beta 1 correlates with aberrant expression of TGF-beta receptor II in human B-cell lymphoma cell lines. Blood. 109(12):5301-5307, 2007.

  38. Cui, W., Taub, D.D., Gardner, K.: qPrimerDepot: a primer database for quantitative real time PCR. Nucleic Acids Res. 35(Database issue):D805-D809, 2007.

  39. Dissanayake, S.K., Wade, M., Johnson, C.E., O'Connell, M.P., Leotlela, P.D., French, A.D., Shah, K.V., Hewitt, K.J., Rosenthal, D.T., Indig, F.E., Jiang, Y., Nickoloff, B.J., Taub, D.D., Trent, J.M., Moon, R.T., Bittner, M., Weeraratna, A.T.: The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J. Biol. Chem. 282(23):17259-17271, 2007.

  40. Ferrucci, L., Guralnik, J.M., Bandinelli, S., Semba, R.D., Lauretani, F., Corsi, A., Ruggiero, C., Ershler, W.B., Longo, D.L.: Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers. Br. J. Haematol. 136(6):849-855, 2007.

  41. Galban, C.J., Ling, S.M., Galban, C.J., Taub, D.D., Gurkan, I., Fishbein, K.W., Spencer, R.G.: Effects of knee injection on skeletal muscle metabolism and contractile force in rats. Osteoarthritis Cartilage. 15(5):550-558, 2007.

  42. Giri, B., Dixit, V.D., Ghosh, M.C., Collins, G.D., Khan, I.U., Madara, K., Weeraratna, A.T., Taub, D.D.: CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. Eur. J. Immunol. 37(8):2104-2116, 2007.

  43. Godlove, J., Chiu, W.K., Weng, N.P.: Gene expression and generation of CD28-CD8 T cells mediated by interleukin 15. Exp. Gerontol. 42(5): 412-415, 2007.

  44. Hayun, M., Okun, E., Hayun, R., Gafter, U., Albeck, M., Longo, D.L., Sredni, B.: Synergistic effect of AS101 and Bryostatin-1 on myeloid leukemia cell differentiation in vitro and in an animal model. Leukemia. 21(7):1504-1513, 2007.

  45. Leotlela, P.D., Wade, M.S., Duray, P.H., Rhode, M.J., Brown, H.F., Rosenthal, D.T., Dissanayake, S.K., Earley, R., Indig, F.E., Nickoloff, B.J., Taub, D.D., Kallioniemi, O.P., Meltzer, P., Morin, P.J., Weeraratna, A.T.: Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility. Oncogene. 26(26):3846-3856, 2007.

  46. Lustig, A., Weeraratna, A.T., Wood, W.W. 3rd, Teichberg, D., Bertak, D., Carter, A., Poosala, S., Firman, J., Becker, K.G., Zonderman, A.B., Longo, D.L., Taub, D.D.: Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus. Cell Immunol. 245(1):42-61, 2007.

  47. McKinstry, K.K., Golech, S., Lee, W.H., Huston, G., Weng, N.P., Swain, S.L.: (Rapid default transition of CD4 T cell effectors to functional memory cells. J. Exp. Med. [Epub ahead of print]. 2007.

  48. Sredni, B., Geffen-Aricha, R., Duan, W., Albeck, M., Shalit, F., Lander, H.M., Kinor, N., Sagi, O., Albeck, A., Yosef, S., Brodsky, M., Sredni-Kenigsbuch, D., Sonino, T., Longo, D.L., Mattson, M.P., Yadid, G.: Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models. FASEB J. 21(8):1870-1883, 2007.

  49. Stote, K.S., Baer, D.J., Spears, K., Paul, D.R., Harris, G.K., Rumpler, W.V., Strycula, P., Najjar, S.S., Ferrucci, L., Ingram, D.K., Longo, D.L., Mattson, M.P.: A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am. J. Clin. Nutr. 85(4):981-988, 2007.

  50. Weeraratna, A.T., Kalehua, A., Deleon, I., Bertak, D., Maher, G., Wade, M.S., Lustig, A., Becker, K.G., Wood, W. 3rd, Walker, D.G., Beach, T.G., Taub, D.D.: Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Exp. Cell Res. 313(3):450-461, 2007.

  51. Weeraratna, A.T., Taub, D.D.: Microarray data analysis: an overview of design, methodology, and analysis. Methods Mol. Biol. 377:1-16, 2007.

  52. Zou, S., Sinclair, J., Wilson, M.A., Carey, J.R., Liedo, P., Oropeza, A., Kalra, A., de Cabo, R., Ingram, D.K., Longo, D.L., Wolkow, C.A.: Comparative approaches to facilitate the discovery of prolongevity interventions: Effects of tocopherols on lifespan of three invertebrate species. Mech. Ageing Dev. 128(2):222-226, 2007.

  53. Cha SC, Kwak LW, Ruffini PA, Qin H, Neelapu S, Biragyn A. Cloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera. J. Immunol. Methods. 312(1-2):79-93, 2006.

  54. Chiu, W.K., Fann, M., Weng, N.P.: Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines. J. Immunol. 177(11):7802-7810, 2006.

  55. Dawson, H.D., Collins, G., Pyle, R., Key, M., Weeraratna, A., Deep-Dixit, V., Nadal, C.N., Taub, D.D.: Direct and indirect effects of retinoic acid on human Th2 cytokine and chemokine expression by human T lymphocytes. BMC Immunol. 7:27, 2006.

  56. Dixit, V.D., Weeraratna, A.T., Yang, H., Bertak, D., Cooper-Jenkins, A., Riggins, G.J., Eberhart, C.G., Taub, D.D.: Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility. J. Biol. Chem. 281(24):16681-16690, 2006.

  57. Ershler, W.B., Longo, D.L.: A report card for geriatric oncology: borderline pass, improvement needed. J. Gerontol. A Biol. Sci. Med. Sci. 61(7):688, 2006.

  58. Fann, M., Godlove, J.M., Catalfamo, M., Wood, W.H. 3rd, Chrest, F.J., Chun, N., Granger, L., Wersto, R., Madara, K., Becker, K., Henkart, P.A., Weng, N.P.: Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response. Blood. 108(10):3363-3370, 2006.

  59. Feng, Y., Yuan, J.H., Maloid, S.C., Fisher, R., Copeland, T.D., Longo, D.L., Conrads, T.P., Veenstra, T.D., Ferris, A., Hughes, S., Dimitrov, D.S., Ferris, D.K.: Pole-like kinase 1-mediated phosphorylation of the GTP-binding protein Ran is important for bipolar spindle formation. Biochem. Biophys. Res. Commun. 349(1):144-152, 2006.

  60. Ferrucci, L., Maggio, M., Bandinelli, S., Basaria, S., Lauretani, F., Ble, A., Valenti, G., Ershler, W.B., Guralnik, J.M., Longo, D.L.: Low testosterone levels and the risk of anemia in older men and women. Arch. Intern. Med. 166(13):1380-1388, 2006.

  61. Lee, G.D., Longo, D.L., Wang, Y., Rifkind, J.M., Abdul-Raman, L., Mamczarz, J.A., Duffy, K.B., Spangler, E.L., Taub, D.D., Mattson, M.P., Ingram, D.K.: Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy. Clin. Cancer Res. 12(1):198-205, 2006.

  62. Longo, D.L.: Idiotype vaccination in follicular lymphoma: knocking on the doorway to cure. J. Natl. Cancer. Inst. 98(18):1263-1265, 2006.

  63. Maggio, M., Guralnik, J.M., Longo, D.L., Ferrucci, L.: Interleukin-6 in aging and chronic disease: a magnificent pathway. J. Gerontol. A Biol. Sci. Med. Sci. 61(6):575-584, 2006.

  64. McHutchison, J.G., Manns, M.P., Longo, D.L.: Definition and management of anemia in patients infected with hepatitis C virus. 26(4):389-398, 2006.

  65. Palaniappan, R., Singh, S., Singh, U.P., Singh, R., Ades, E.W., Briles, D.E., Hollingshead, S.K., Royal, W. 3rd, Sampson, J.S., Stiles, J.K., Taub, D.D., Lillard, J.W. Jr.: CCL5 modulates pneumococcal immunity and carriage. J. Immunol. 176(4):2346-2356, 2006.

  66. Schiavo, R., Baatar, D., Olkhanud, P., Indig, F.E., Restifo, N., Taub, D., Biragyn, A.: Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8+ T cell responses. Blood. 107(12):4597-4605. 2006.

  67. Swain, S.L., Agrewala, J.N., Brown, D.M., Jelley-Gibbs, D.M., Golech, S., Huston, G., Jones, S.C., Kamperschroer, C., Lee, W.H., McKinstry, K.K., Roman, E., Strutt, T., Weng, N.P.: CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza. Immunol. Rev. 211:8-22, 2006.

  68. Weng, N.P.: Aging of the immune system: how much can the adaptive immune system adapt? Immunity. 24(5):495-499, 2006.

  69. Biragyn, A.: Defensins - Non-antibiotic use for vaccine development. Curr. Protein Pept. Sci. 6(1):53-60, 2005.

  70. Ble, A., Windham, B.G., Bandinelli, S., Taub, D.D., Volpato, S., Bartali, B., Tracy, R.P., Guralnik, J.M., Ferrucci, L.: Relation of plasma leptin to C-reactive protein in older adults (from the Invecchiare nel Chianti Study). Am. J. Cardiol. 96(7):991-995, 2005.

  71. Chabner, BA, Longo, DL. (Eds.), Cancer Chemotherapy and Biotherapy: Principles and Practice, 4th edition. Philadelphia: Lippincott Williams and Wilkins, 2005, pp. 1000.

  72. Dixit, V.D., Taub, D.D.: Ghrelin and immunity: A young player in an old field. Exp. Gerontol. 40(11):900-910, 2005.

  73. Ershler, W.B., Sheng, S., McKelvey, J., Artz, A.S., Denduluri, N., Tecson, J., Taub, D.D., Brant, L.J., Ferrucci, L., Longo, D.L.: Serum erythropoietin and aging: a longitudinal analysis. J Am Geriatr Soc. 53(8):1360-1365, 2005.

  74. Fann, M., Chiu, W.K., Wood, W.H. 3rd, Levine, B.L., Becker, K.G., Weng, N.P.: Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging. Immunol. Rev. 205:190-206, 2005.

  75. Ferrucci, L., Corsi, A., Lauretani, F., Bandinelli, S., Bartali, B., Taub, D.D., Guralnik, J.M., Longo, D.L.: The origins of age-related pro-inflammatory state. Blood. 105(6):2294-2299, 2005.

  76. Ferrucci, L., Guralnik, J.M., Woodman, R.C., Bandinelli, S., Lauretani, F., Corsi, A.M., Chaves, P.H., Ershler, W.B., Longo, D.L.: Proinflammatory state and circulating erythropoietin in persons with and without anemia. Am. J. Med. 118(11):1288, 2005.

  77. Freebern, W.J., Haggerty, C.M., Montano, I., McNutt, M.C., Collins, I., Graham, A., Chandramouli, G.V., Stewart, D.H., Biebuyck, H.A., Taub, D.D., Gardner, K.: Pharmacologic profiling of transcriptional targets deciphers promoter logic. Pharmacogenomics J. 5(5):305-323, 2005.

  78. Gulmann, C., Espina, V., Petricoin, E. 3rd, Longo, D.L., Santi, M., Knutsen, T., Raffeld, M., Jaffe, E.S., Liotta, L.A., Feldman, A.L.: Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma. Clin. Cancer Res. 11(16):5847-5855, 2005.

  79. Kusaba, H., Ghosh, P., Derin, R., Buchholz, M., Sasaki, C., Madara, K., Longo, D.L.: Interleukin-12-induced IFN-g production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR). J. Biol. Chem. 280(2):1037-1043, 2005.

  80. Li, Y., Zhi, W., Wareski, P., Weng, N.P.: IL-15 activates telomerase and minimizes telomere loss and may preserve the replicative life span of memory CD8+ T cells in vitro. J. Immunol. 174(7):4019-4024, 2005.

  81. Longo, D.L.: Adjuvant therapy for localized breast cancer: radiation therapy improves disease control in women over age 50 years, but not in women over age 70 years. Postgrad. Med. 117(6):8, 2005.

  82. Longo, D.L.: Chimera: from bane to blessing. Blood. 106:1890-1891, 2005.

  83. Longo, D.L.: Closing in on a killer: anemia in elderly people. J. Gerontol. A Biol. Sci. Med. Sci. 60(6):727-728, 2005.

  84. Longo, D.L.: Radiation therapy in Hodgkin disease: why risk a Pyrrhic victory? J. Natl. Cancer Inst. 97(19):1394-1395, 2005.

  85. Longo, D.L.: Radiation therapy may improve survival of premenopausal women with breast cancer involving axillary lymph nodes. Postgrad. Med. 117(4):6, 2005.

  86. Nguyen, D.H., Giri, B., Collins, G., Taub, D.D.: Dynamic reorganization of chemokine receptors, cholesterol, lipid rafts, and adhesion molecules to sites of CD4 engagement. Exp Cell Res. 304(2):559-569, 2005.

  87. Rezanka, L.J., Kenny, J.J., Longo, D.L.: 2 BCR or NOT 2 BCR - receptor dilution: a unique mechanism for preventing the development of holes in the protective B cell repertoire. Immunobiology. 210(10):769-774, 2005.

  88. Rezanka, L.J., Kenny, J.J., Longo, D.L.: Dual isotype expressing B cells [k(+)/l(+)] arise during the ontogeny of B cells in the bone marrow of normal nontransgenic mice. Cell Immunol. 238(1):38-48, 2005.

  89. Sakatani, T., Kaneda, A., Iacobuzio-Donahue, C.A., Carter, M.G., Witzel, S.D., Okano, H., Ko, M.S., Ohlsson, R., Longo, D.L., Feinberg, A.P.: Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science. 307(5717):1976-1978, 2005.

  90. Sasaki, C.Y., Barberi, T.J., Ghosh, P., Longo, D.L.: Phosphorylation of RelA/p65 on serine 536 defines an Ik Ba -independent NF-k B pathway. J. Biol. Chem. 280(41):34538-34547, 2005.

  91. Taub, D.D., Longo, D.L.: Insights into thymic aging and regeneration. Immunol. Rev. 205:72-93, 2005.

  92. Dawson, H., Collins, G., Pyle, R., Deep-Dixit, V., Taub, D.D. The immunoregulatory effects of homocysteine and its intermediates on T-lymphocyte function. Mech. Ageing Dev. 125(2):107-110, 2004.

  93. de Mello Coelho, V., Nguyen, D., Giri, B., Bunbury, A., Schaffer, E., Taub, D.D. Quantitative differences in lipid raft components between murine CD4+ and CD8+ T cells. BMC Immunol. 5(1):2, 2004.

  94. Dixit, V.D., Schaffer, E.M., Pyle, R.S., Collins, G.D., Sakthivel, S.K., Palaniappan, R., Lillard, J.W. Jr., Taub, D.D.: Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J. Clin. Invest. 114(1):57-66, 2004.

  95. Ferrucci, L., Corsi, A., Lauretani, F., Bandinelli, S., Bartali, B., Taub, D.D., Guralnik, J.M., Longo, D.L.: The origins of age-related pro-inflammatory state. Blood. [Epub ahead of print], 2004.

  96. Hess, K., Yang, Y., Golech, S., Sharov, A., Becker, K.G., Weng, N.P.: Kinetic assessment of general gene expression changes during human naive CD4+ T cell activation. Int. Immunol. 16(12):1711-1721, 2004.

  97. Hu, L., Dixit, V.D., de Mello-Coelho, V., Taub, D.D.: Age-associated alterations in CXCL1 chemokine expression by murine B cells. BMC Immunol. 25(1): 15, 2004.

  98. Kalehua, A.N., Nagel, J.E., Whelchel, L.M., Gides, J.J., Pyle, R.S., Smith, R.J., Kusiak, J.W., Taub, D.D.: Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration. Exp. Cell Res. 297(1): 197-211, 2004.

  99. Lin, H.J., Wang, X., Shaffer, K.M., Sasaki, C.Y., Ma, W.: Characterization of H2O2-induced acute apoptosis in cultured neural stem/progenitor cells. FEBS Lett. 570(1-3): 102-106, 2004.

  100. Mattson, M.P., Taub, D.D.: Ancient viral protein enrages astrocytes in multiple sclerosis. Nat. Neurosci. 7(10): 1021-1023, 2004.

  101. Nagel, J.E., Smith, R.J., Shaw, L., Bertak, D., Dixit, V.D., Schaffer, E.M., Taub, D.D.: Identification of genes differentially expressed in T cells following stimulation with the chemokines CXCL12 and CXCL10. BMC Immunol. 5(1): 17, 2004.

  102. Nguyen, D.H., Espinoza, J.C., Taub, D.D.: Cellular cholesterol enrichment impairs T cell activation and chemotaxis. Mech. Ageing Dev. 125(9): 641-650, 2004.

  103. Nguyen, D.H., Taub, D.D.: Targeting lipids to prevent HIV infection. Mol. Interv. 4(6): 318-320, 2004.

  104. O'Farrell, T.J., Ghosh, P., Dobashi, N., Sasaki, C.Y., Longo, D.L.: Comparison of the effect of mutant and wild-type p53 on global gene expression. Cancer Res. 64(22): 8199-8207, 2004.

  105. Olsson, N., Taub, D.D., Nilsson, G.: Regulation of mast cell migration by T and T cytokines: identification of tumour necrosis factor-a and interleukin-4 as mast cell chemotaxins. Scand. J. Immunol. 59(3): 267-272, 2004.

  106. Rangel, L.B., Agarwal, R., Sherman-Baust, C.A., de Mello-Coelho, V., Pizer, E.S., Ji, H., Taub, D.D., Morin, P.J.: Anomalous expression of the HLA-DR a and b chains in ovarian and other cancer. Cancer Biol. Ther. 3(10), 2004.

  107. Ruffini, P.A., Biragyn, A., Coscia, M., Harvey, L.K., Cha, S.C., Bogen, B., Kwak, L.W.: Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis. J. Leukoc. Biol. 76(1): 77-85, 2004.

  108. Singh, U.P., Singh, S., Ravichandran, P., Taub, D.D., Lillard, J.W. Jr.: Viral macrophage-inflammatory protein-II: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts. J. Immunol. 173(9): 5509-5516, 2004.

  109. Sredni, B., Weil, M., Khomenok, G., Lebenthal, I., Teitz, S., Mardor, Y., Ram, Z., Orenstein, A., Kershenovich, A., Michowiz, S., Cohen, Y.I., Rappaport, Z.H., Freidkin, I., Albeck, M., Longo, D.L., Kalechman, Y. Ammonium trichloro(dioxoethylene-o,o')tellurate (AS101) sensitizes tumors to chemotherapy by inhibiting the tumor interleukin 10 autocrine loop. Cancer Res. 64(5): 1843-1852, 2004.

  110. Takahashi, K., Reynolds, M., Ogawa, N., Longo, D.L., Burdick, J.: Augmentation of T-cell apoptosis by immunosuppressive agents. Clin. Transplant. 18 Suppl 12: 72-75, 2004.

  111. Taub, D.D., Mikovits, J.A., Nilsson, G., Schaffer, E.M., Key, M.L., Petrow-Sadowski, C., Ruscetti, F.W.: Alterations in mast cell function and survival following in vitro infection with human immunodeficiency viruses-1 through CXCR4. Cell Immunol. 230(2): 65-80. 2004.

  112. Weeraratna, A.T., Nagel, J.E., de Mello-Coelho, V., Taub, D.D. Gene expression profiling: from microarrays to medicine. J. Clin. Immunol. 24(3): 213-224, 2004.

  113. Westin, E.H., Longo, D.L.: Lymphoma and myeloma in older patients. Semin. Oncol. 31(2): 198-205, 2004.

  114. Yuan, J.H., Feng, Y., Fisher, R.H., Maloid, S., Longo, D.L., Ferris, D.K.: Polo-like kinase 1 inactivation following mitotic DNA damaging treatments is independent of ataxia telangiectasia mutated kinase. Mol. Cancer Res. 2(7): 417-426, 2004.

  115. Artz, A.S., Ershler, W.B., Longo, D.L. Pneumococcal vaccination and revaccination of older adults. Clin. Microbiol. Rev. 16(2): 308-318, 2003. [Abs]

  116. Dixit, V.D., Mielenz, M., Taub, D.D., Parvizi, N. Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C- and nitric oxide-dependent mechanism. Endocrinology. 144(12): 5595-5603, 2003.
    117. [Abs]

  117. Ferrucci, L., Guralnik, J.M., Cavazzini, C., Bandinelli, S., Lauretani, F., Bartali, B., Repetto, L., Longo, D.L. The frailty syndrome: a critical issue in geriatric oncology. Crit. Rev. Oncol. Hematol. 46(2): 127-137, 2003.[Abs]

  118. Kalayjian, R.C., Landay, A., Pollard, R.B., Taub, D.D., Gross, B.H., Francis, I.R., Sevin, A., Pu, M., Spritzler, J., Chernoff, M., Namkung, A., Fox, L., Martinez, A., Waterman, K., Fiscus, S.A., Sha, B., Johnson, D., Slater, S., Rousseau, F., Lederman, M.M.; Adult AIDS Clinical Trial Group 5015 Protocol Team; Adult AIDS Clinical Trial Group 5113 Protocol Team. Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes. J. Infect. Dis. 187(12):1924-1933, 2003.
    119. [Abs]

  119. Lillard, J.W. Jr., Singh, U.P., Boyaka, P.N., Singh, S., Taub, D.D., McGhee, J.R. MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity. Blood. 101(3): 807-814, 2003.
    120. [Abs]

  120. Longo, D.L.: Immunology of aging. In: Paul, W.E. (Ed.) Fundamental Immunology, 5th edition, Philadelphia, Lippincott Williams, and Wilkins, 2003, pp. 1043-1075.

  121. Longo, D.L. Radiation therapy in the treatment of Hodgkin's disease--do you see what I see? J. Natl. Cancer Inst. 95(13): 928-929, 2003.
    122. [Journal]

  122. Nguyen, D.H., Taub, D.D. Inhibition of chemokine receptor function by membrane cholesterol oxidation. Exp. Cell Res. 291(1): 36-45, 2003.
    123. [Abs]

  123. Nguyen, D.H., Taub, D.D. Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity. Exp. Cell Res. 285(2): 268-277, 2003.
    124. [Abs]

  124. Shack, S., Wang, X-T., Kokkonen, G.C., Gorospe, M., Longo, D.L., Holbrook, N.J. Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity. Mol. Cell Biol. 23(7): 2407-2414, 2003.
    125. [Abs]

  125. Sharov, A.A., Piao, Y., Matoba, R., Dudekula, D.B., Qian, Y., VanBuren, V., Falco, G., Martin, P.R., Stagg, C.A., Bassey, U.C., Wang, Y., Carter, M.G., Hamatani, T., Aiba, K., Akutsu, H., Sharova, L., Tanaka, T.S., Kimber, W.L., Yoshikawa, T., Jaradat, S.A., Pantano, S., Nagaraja, R., Boheler, K.R., Taub, D., Hodes, R.J., Longo, D.L., Schlessinger, D., Keller, J., Klotz, E., Kelsoe, G., Umezawa, A., Vescovi, A.L., Rossant, J., Kunath, T., Hogan, B.L., Curci, A., D'Urso, M., Kelso, J., Hide, W., Ko, M.S.H. Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol. 1: 410-419, 2003.
    126. [Abs]

  126. Singh, U.P., Singh, S., Taub, D.D., Lillard, J.W. Jr. Inhibition of IFN-g-inducible protein-10 abrogates colitis in IL-10-/- mice. J. Immunol. 171(3): 1401-1406, 2003.
    127. [Abs]

  127. Son, N.H., Joyce, B., Hieatt, A., Chrest, F.J., Yanovski, J., Weng, N.P. Stable telomere length and telomerase expression from naive to memory B-lymphocyte differentiation. Mech. Ageing. Dev. 124(4): 427-432, 2003.
    128. [Abs]

  128. Yano, S., Ghosh, P., Kusaba, H., Buchholz, M., Longo D.L. Effect of promoter methylation on the regulation of IFN-g gene during in vitro differentiation of human peripheral blood T cells into a Th2 population. J. Immunol. 171(5): 2510-2516, 2003.
    129. [Abs]

  129. Espinoza-Delgado, E., and Longo, D.L.: Non-Hodgkin's lymphoma. In: Laughlin, M.J. and Lazarus, H.M. (Eds.): Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Totowa, N.J., Humana Press, 2002, pp 83-99.

  130. Ghosh, P., Buchholz, M.A., Yano, S., Taub, D., Longo, D.L. Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. Blood. 9(12): 4517-4524, 2002.
    131. [Abs]

  131. Hodes, R.J., Hathcock, K.S., Weng, N.P. Telomeres in T and B cells. Nat. Rev. Immunol. 2(9): 699-706, 2002.
    132. [Abs]

  132. Hu, L., Rezanka, L.J., Mi. Q.S., Lustig, A., Taub, D.D., Longo, D.L., Kenny J.J. T15-idiotype-negative B cells dominate the phosphocholine binding cells in the preimmune repertoire of T15i knockin mice. J. Immunol. 168(3): 1273-1280, 2002.
    133. [Abs]

  133. Liu, K., Catalfamo, M., Li, Y., Henkart, P.A., Weng, N.P. IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells. Proc. Natl. Acad. Sci. USA. 99(9): 6192-6197, 2002.
    134. [Abs]

  134. Longo, D.L. DR's orders: human antibody kills tumors by direct signaling. Nat. Med. 8(8): 781-783, 2002.
    135. [Abs]

  135. Longo, D.L. Genetic abnormalities in lymphoid malignancies. In: Vogelstein, B., and Kinzler, K.W. (Eds.): The Genetic Basis of Human Cancer, 2nd edition, New York, McGraw-Hill, 2002, pp. 785-801.

  136. Luo, Y., Long, J.M., Lu, C., Chan, S.L., Spangler, E.L., Mascarucci, P., Raz, A., Longo, D.L., Mattson, M.P., Ingram, D.K., and Weng, N.P. A link between maze learning and hippocampal expression of neuroleukin and its receptor gp78. J. Neurochem. 80: 354-361, 2002.
    137. [Abs]

  137. Mascarucci, P., Taub, D., Saccani, S., Paloma, M.A., Dawson, H., Roth, G.S., Lane, M.A., Ingram, D.K. Cytokine responses in young and old rhesus monkeys: effect of caloric restriction. J. Interferon. Cytokine Res. 22(5): 565-571, 2002.
    138. [Abs]

  138. Mi., Q.S., Rezanka, L.J., Lustig, A., Zhou, L., Longo, D.L., Kenny, J.J. The M603 idiotype is lost in the response to phosphocholine in terminal deoxynucleotidyl transferase-deficient mice. Eur. J. Immunol. 32(4): 1139-1146, 2002.
    139. [Abs]

  139. Nguyen, D.H., Taub, D. Cholesterol is essential for macrophage inflammatory protein 1 beta binding and conformational integrity of CC chemokine receptor 5. Blood. 99(12): 4298-4306, 2002.
    140. [Abs]

  140. Nguyen, D.H., Taub, D. CXCR4 function requires membrane cholesterol: implications for HIV infection. J. Immunol. 168(8): 4121-4126, 2002.
    141. [Abs]

  141. Oliveira, S.H., Taub, D.D., Nagel, J., Smith, R., Hogaboam, C.M., Berlin, A., Lukacs, N.W. Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis. Blood. 100(13): 4291-4297, 2002.
    142. [Abs]

  142. Rosenwald, A., Wright, G., Chan, W.C., Connors, J.M., Campo, E., Fisher, R.I., Gascoyne, R.D., Muller-Hermelink, H.K., Smeland, E.B., Giltnane, J.M., Hurt, E.M., Zhao, H., Averett, L., Yang, L., Wilson, W.H., Jaffe, E.S., Simon, R., Klausner, R.D., Powell, J., Duffey, P.L., Longo, D.L., Greiner, T.C., Weisenburger, D.D., Sanger, W.G., Dave, B.J., Lynch, J.C., Vose, J., Armitage, J.O., Montserrat, E., Lopez-Guillermo, A., Grogan, T.M., Miller, T.P., LeBlanc, M., Ott, G., Kvaloy, S., Delabie, J., Holte, H., Krajci, P., Stokke, T., Staudt, L.M. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med. 346(25): 1937-1947, 2002.
    143. [Abs]

  143. Raziuddin, A., Longo, D.L., Bennett, M., Winkler-Pickett, R., Ortaldo, J.R., Murphy, W.J. Increased bone marrow allograft rejection by depletion of donor NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens. Blood 100: 3026-3033, 2002.
    144. [Abs]

  144. Szocinski, J.L., Khaled, A.R., Hixon, J., Halverson, D., Funakoshi, S., Fanslow, W.C., Boyd, A., Taub, D.D., Durum, S.K., Siegall, C.B., Longo, D.L., Murphy, W.J. Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax. Blood. 100(1): 217-223, 2002.
    145. [Abs]

  145. Weng, N.P. Regulation of telomerase expression in human lymphocytes. Springer Semin. Immunopathol. 24(1): 23-33, 2002.
    146. [Abs]

  146. Weng, N.P., Liu, K., Catalfamo, M., Li, Y., Henkart, P.A. L-15 is a growth factor and an activator of CD8 memory T cells. Ann. NY Acad. Sci. 975: 46-56, 2002.
    147. [Abs]

  147. Wilson, W.H., Grossbard, M.L., Pittaluga, S., Cole, D., Pearson, D., Drbohlav, N., Steinberg, S.M., Little, R.F., Janik, J., Gutierrez, M., Raffeld, M., Staudt, L., Cheson, B.D., Longo, D.L., Harris, N., Jaffe, E.S., Chabner, B.A., Wittes, R., Balis, F. Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy. Blood. 99(8): 2685-2693, 2002.
    148. [Article]

  148. Yang, F., Li, X., Sharma, M., Sasaki, C.Y., Longo, D.L., Lim, B., Sun, Z. Linking ß-catenin to androgen-signaling pathway. J. Biol. Chem. 277(13): 11336-11344, 2002.
    149. [Abs]

  149. Adamson, J.W., and Longo, D.L. Anemia and polycythemia. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 348-354.

  150. Armitage, J.O., and Longo, D.L. Malignancies of lymphoid cells. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 715-727.

  151. Crow, M., Taub, D.D., Cooper, S., Broxmeyer, H.E., Sarris, A.H. Human recombinant interferon-inducible protein-10: intact disulfide bridges are not required for inhibition of hematopoietic progenitors and chemotaxis of T lymphocytes and monocytes. J. Hematother. Stem. Cell. Res.10(1): 147-156, 2001.
    152. [Abs]

  152. Fauci, A.S., and Longo, D.L. The human retroviruses. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 1131-1135.

  153. Feng, Y., Longo, D.L., Ferris, D.K. Polo-like kinase interacts with proteasomes and regulates their activity. Cell. Growth Differ. 12(1): 29-37, 2001.
    154. [Abs]

  154. Fenton, R.G., and Longo, D.L. Cell biology of cancer. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 509-517.

  155. Henry, P.H., and Longo, D.L. Enlargement of lymph nodes and spleen. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 360-365.

  156. Janik, J.E., Miller, L.L., Korn, E.L., Stevens, D., Curti, B.D., Smith, J.W., 2nd, Sznol, M., Conlon, K.C., Sharfman, W., Urba, W.J., Gause, B.L., Longo, D.L. A prospective randomized phase II trial of GM-CSF priming to prevent topotecan-induced neutropenia in chemotherapy-naive patients with malignant melanoma or renal cell carcinoma. Blood 97(7): 1942-1946, 2001.
    157. [Abs]

  157. Lillard, J.W. Jr, Boyaka, P.N., Taub, D.D., McGhee, J.R. RANTES potentiates antigen-specific mucosal immune responses. J. Immunol. 166(1):162-9, 2001.
    158. [Abs]

  158. Liu, K., Hodes, R.J. and Weng, N. Cutting edge: Telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation. J. Immunol. 166: 4826-4830, 2001.
    159. [Abs]

  159. Liu, K., Li, Y., Prabhu, V., Young, L., Becker, K.G., Munson, P.J. and Weng, N.P. Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells. J. Immunol. 166(12):7335-7344, 2001.
    160. [Abs]

  160. Longo, D.L. Approach to the patient with cancer. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 491-497.

  161. Longo, D.L. Hodgkin’s disease: chemotherapy. In: Rakel, R.E., and Bope, E.T. (Eds.): Conn’s Current Therapy 2001, Philadelphia, W.B. Saunders, 2001, pp 429-435.

  162. Longo, D.L. Plasma cell disorders. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 727-733.

  163. Luo, Y., Long, J.M., Spangler, E.L., Longo, D.L., Ingram, D.K., and Weng, N.P. Identification of maze learning associated genes in rat hippocampus by cDNA microarray. J. Mol. Neurosci. 17: 127-134, 2001.
    164. [Abs]

  164. Mayne, M., Cheadle, C., Soldan, S.S., Cermelli, C., Yamano, Y., Akhyani, N., Nagel, J.E., Taub, D.D., Becker, K.G., Jacobson, S. Gene expression profile of herpesvirus-infected T cells obtained using immunomicroarrays: induction of proinflammatory mechanisms.J. Virol. 75(23): 11641-11650, 2001.
    165. [Abs]

  165. Murphy, W.J., and Longo, D.L. Alternative strategies other than growth hormone for the treatment of immune diseases. Trends Immunol. 22: 15-16, 2001.

  166. Murphy, W.J., Koh, C.Y., Raziuddin, A., Bennett, M., and Longo, D.L. Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies. Immunol. Rev. 181: 279-289, 2001.
    167. [Abs]

  167. Perry, M.C., and Longo, D.L. Late consequences of cancer and its treatment. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 650-653.

  168. Sausville, E.A., and Longo, D.L. Principles of cancer treatment. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 530-547.

  169. Srivastava, R.K., Mattson, M.P., and Longo, D.L. Cytoskeletal involvement in apoptosis. In: Mattson, M.P., Estus, S., and Rangnekar, V.M. (Eds.): Programmed Cell Death Volume I Cellular and Molecular Mechanisms, Amsterdam, Elsevier, 2001, pp. 237-267.

  170. Tiberghien, P., Ferrand, C., Lioure, B., Milpied, N., Angonin, R., Deconinck, E., Certoux, J-M., Robinet, E., Saas, P., Petracca, B., Juttner, C., Reynolds, C.W., Longo, D.L., Herve, P., and Cahn, J-Y. Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft. Blood 97: 63-72, 2001.

  171. The Editors: The practice of medicine. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., and Jameson, J.L. (Eds.): Harrison's Principles of Internal Medicine, 15th Edition. New York, McGraw-Hill, 2001, pp. 1-5.

  172. Westin, E.H., and Longo, D.L. T-small cell disorders. Curr. Treat. Options Oncol. 2: 225-235, 2001.

  173. Alexandroff, A.B., Jackson, A.M., Paterson, T., Haley, J.L., Ross, J.A., Longo, D.L., Murphy, W.J., James, K., Taub, D.D. Role for CD40-CD40 ligand interactions in the immune response to solid tumours. Mol. Immunol. 37(9): 515-526, 2000.
    174. [Abs]

  174. Arun, B., Curti, B.D., Longo, D.L., Stevens, D., Alvord, W.G., Gause, B.L., Watson, T., Kopp, W.C., Janik, J.E. Elevations in serum soluble interleukin-2 receptor levels predict relapse in patients with hairy cell leukemia. Cancer J. Sci. Am. 6: 21-24, 2000.
    175. [Abs]

  175. Chase, D., Serafinas, C., Ashcroft, N., Kosinski, M., Longo, D., Ferris, D.K., Golden. A. The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans. Genesis 26: 26-41, 2000.
    176. [Abs]

  176. Dunn, B.K., and Longo, D.L. Molecular biology and biological markers. In: Hunter, C.P., Johnson, K.A., and Muss, H.B. (Eds.): Cancer in the Elderly, New York, Marcel Dekker, 2000, pp. 69-121.

  177. Kalechman, Y., Longo, D.L., Catane, R., Shani, A., Albeck, M., Sredni, B. Synergistic anti-tumoral effect of paclitaxel (taxol)+AS101 in a murine model of B16 melanoma: association with ras-dependent signal-transduction pathways. Int. J. Cancer 86(2): 281-288, 2000.
    178. [Abs]

  178. Kalehua, A.N., Taub, D.D., Baskar, P.V., Hengemihle, J., Munoz, J., Trambadia, M., Speer, D.L., De Simoni, M.G., Ingram, D.K. Aged mice exhibit greater mortality concomitant to increased brain and plasma TNF-alpha levels following intracerebroventricular injection of lipopolysaccharide. Gerontology. 46(3): 115-128, 2000.
    179. [Abs]

  179. Kaufman, D., and Longo, D.L. Hodgkin’s disease. In: Abeloff, M.D., Armitage, J.O., Lichter, A.S., and Niederhuber, J.E. (Eds.): Clinical Oncology, 2nd Edition. Philadelphia, Churchill-Livingstone, 2000, pp. 2620-2657.

  180. Kenny, J. J., Derby E.G., Yoder, J.A., Hill, S.A., Fischer, R.T., Tucker, P.W., Claflin, J.L., Longo, D.L. Positive and negative selection of antigen-specific B cells in transgenic mice expressing variant forms of the V(H)l (T15) heavy chain. Int. Immunol. 12(6): 873-885, 2000.
    181. [Abs]

  181. Kenny, J.J., Lustig, A., and Longo, D.L. Positive selection of low affinity autoreactive B cells. Curr. Top. Microbiol. Immunol. 252: 39-45, 2000.
    182. [Abs]

  182. Kenny, J. J., Rezanka, L.J., Lustig, A., Fischer, R.T., Yoder, J., Marshall, S., Longo, D.L. Autoreactive B cells escape clonal deletion by expressing multiple antigen receptors. J. Immunol. 164(8): 4111-4119, 2000.
    183. [Abs]

  183. Kondo, T., Morita, K., Watarai, Y., Auerbach, M.B., Taub, D.D., Novick, A.C., Toma, H., Fairchild, R.L. Early increased chemokine expression and production in murine allogeneic skin grafts is mediated by natural killer cells. Transplantation. 69(5): 969-77, 2000.
    184. [Abs]

  184. Longo, D.L. Lymphomas: complexity, not chaos. Curr. Opin. Oncol. 12(5): 379-382, 2000.

  185. Longo, D.L., Duffey, P.L., Gribben, J.G., Jaffe, E.S., Curti, B.D., Gause, B.L., Janik, J.E., Braman V.M., Esseltine, D., Wilson, W.H., Kaufman, D, Wittes, R.E., Nadler, L.M., and Urba, W.J. Combination chemotherapy followed by an immunotoxin (anti-B4-blocked ricin) in patients with indolent lymphoma: results of a phase II study. Cancer J. Sci. Am. 6: 146-150, 2000.
    186. [Abs]

  186. Mi, Q.S., Zhou, L., Schulze, D.H., Fischer, R.T., Lustig, A., Rezanka, L.J., Donovan, D.M., Longo, D.L., Kenny, J. J. Highly reduced protection against streptococcus pneumoniae after deletion of a single heavy chain gene in mouse. Proc. Natl. Acad. Sci. USA 97(11): 6031-6036, 2000.
    187. [Abs]

  187. Murphy, W.J., Longo, D.L. Growth hormone as an immunomodulating agent. Immunol. Today 21: 211-213, 2000.
    188. [Abs]

  188. Nilsson, G., Metcalfe, D.D., Taub, D.D. Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response. Immunology. 99(2):314-319, 2000.
    189. [Abs]

  189. Raziuddin, A., Bennett, M., Winkler-Pickett, R., Ortaldo, J.R., Longo, D.L., and Murphy, W.J. Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H-2b bone marrow allografts. Blood 95: 3840-3844, 2000.
    190. [Abs]

  190. Sasaki, C.Y., Lin, H., Morin, P.J., and Longo, D.L. Truncation of the extracellular region abrogates cell contact but retains the growth suppressive activity of E-cadherin. Cancer Res. 60: 7057-7065, 2000.

  191. Son, N., Murray, S., Yanovski, J. Hodes, R.J. and Weng, N. Lineage specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age. J. Immunol. 165: 1191-1196, 2000.
    192. [Abs]

  192. Sredni, B., Longo, D.L., Catane, R., Shani, A., Albeck, M., and Kalechman, Y. Synergistic antitumoral effect of the immunomodulator AS101 plus paclitaxel (Taxol). Association with ras-dependent signal transduction pathways. Exp. Hematol. 28: 1496, 2000.
    193. [Abs]

  193. Taub, D.D. Modified microchemotaxis assays. Methods Mol. Biol. 138: 105-112, 2000.
    194. [Abs]

  194. Weng, N. and Hodes, R.J. The role of telomerase expression and telomere length maintenance in human and mouse. J. Clin. Immunol. 20(4):257-267, 2000.
    195. [Abs]

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Updated: Wednesday January 28, 2009