National Institute on Aging
National Institutes of Health 		NIA Home
Research Programs
Intramural
Bibliography
David Schlessinger, Ph.D.

  1. Tissieres, A., Watson, J.D., Schlessinger, D. and Hollingworth, B.R. (1959). Ribosomes from Escherichia coli. J. Mol. Biol. 1: 221-233.

  2. Schlessinger, D. (1960). Hypochromicity in ribosomes from Escherichia coli. J. Mol. Biol. 2: 92-95.

  3. Tissieres, A., Schlessinger, D. and Gros, Fe. (1960). Amino acid incorporation into proteins by Escherichia coli ribosomes. Proc. Natl. Acad. Sci. Wash. USA 46: 1450-1463.

  4. Marks, P.A., Burka, E.R. and Schlessinger, D. (1962). Protein synthesis in erythroid cells. I. Reticulocyte ribosomes active in stimulating amino acid incorporation. Proc. Natl. Acad. Sci. Wash. 48: 2163-2171.

  5. Schlessinger, D. and Gros, Fe. (1963). Structure and properties of active ribosomes of Escherichia coli. J. Mol. Biol. 7: 350-359.

  6. Spahr, P.F. and Schlessinger, D. (1963). Breakdown of messenger ribonucleic acid by a potassium-activated phosphodiesterase from Escherichia coli. J. Biol Chem. 238: P.C. 2251-2253.

  7. Schlessinger, D. (1963). Protein synthesis by polyribosomes on protoplast membranes of B. megaterium. J. Mol. Biol. 7: 569-582.

  8. Schlessinger, D. (1964). Requirement for K+ and ATP in protein synthesis by Escherichia coli ribosomes. Biochem. Biophys. Acta 80: 473-477.

  9. Meselson, M., Nomura, M., Brenner, S., Davern, C. and Schlessinger, D. (1964). Conservation of ribosomes during bacterial growth. J. Mol. Biol. 9: 696-711.

  10. Schlessinger, D., Marchesi, V.T. and Kwan, B.C.K. (1965). Binding of ribosomes to cytoplasmic reticulum of Bacillus megaterium. J. Bact. 90: 456-466.

  11. Ben Hamida, F. and Schlessinger, D. (1965). Stability of B-galactosidase messenger RNA in Escherichia coli. J. Bact. 90: 1611-1616.

  12. Schlessinger, D. and Ben Hamida, F. (1966). Turnover of protein in Escherichia coli starving for nitrogen. Biochem. Biophys. Acta 119: 171-182. [Abs]

  13. Ben Hamida, F. and Schlessinger, D. (1966). Synthesis and breakdown of RNA in Escherichia coli starving for nitrogen. Biochem. Biophys. Acta 119: 183-191. [Abs]

  14. Mangiarotti, G., Apirion, D. and Schlessinger, D. (1966). Selection of sucrose-dependent Escherichia coli to obtain envelope mutants and fragile cultures. Science 153: 892-894. [Abs]

  15. Maniarotti, G. and Schlessinger, D. (1966). Fragile cultures of Escherichia coli produced by growth in high concentrations of various salts. Nature 211: 761-763. [Abs]

  16. Schlessinger, D. and Apirion, D. (1966). Adaptive changes in the mechanism of protein synthesis occur when Escherichia coli are grown anaerobically, and are demonstrable in vitro. Cold Spring Harbor Symp. Quant. Biol. 31: 680-681.

  17. Mangiarotti, G. and Schlessinger, D. (1966). Polyribosome metabolism in Escherichia coli. I. Extraction of polyribosomes and ribosomal subunits from fragile, growing Escherichia coli. J. Mol. Biol. 20: 123-143. [Abs]

  18. Apirion, D. and Schlessinger, D. (1967). The loss of phenotypic suppression in streptomycin-resistant mutants. Proc. Natl. Acad. Sci. 58: 206-212. [Abs]

  19. Apirion, D. and Schlessinger, D. (1967). Reversion from streptomycin dependence in E. coli by a further change in the ribosome. J. Bacteriol. 94: 1275-1276. [Abs]

  20. Maniarotti, G. and Schlessinger, D. (1967). Polyribosome metabolism. II. Formation and lifetime of messenger RNA molecules, ribosomal subunit couples and polyribosomes. J. Mol. Biol. 29: 395-418.

  21. Schlessinger, D., Mangiarotti, G. and Apirion, D. (1967). The formation and stabilization of 30S - 50S ribosome couples of Escherichia coli. Proc. Natl. Acad. Sci. Wash. 58: 1782-1789. [Abs]

  22. Silengo, L., Schlessinger, D., Mangiarotti, G. and Apirion, D. (1967). Induction of mutations to streptomycin and spectinomycin resistance in Escherichia coli by N-methyl-N'-Nitroso-N-nitrosoguanidine and acridine half mustard ICR-191. Mutation Research 4: 701-703. [Abs]

  23. Wang, T., Luzzatto, L., Apirion, D. and Schlessinger, D. (1968). Comparison of ribosomal proteins from Escherichia coli strains in electrophoresis in a polyacrylamide gel slab. Bacteriological Proceedings 68: 128.

  24. Mangiarotti, G., Apirion, D. Schlessinger, D., and Silengo, L. (1968). Biosynthetic precursors of 30S and 50S ribosomal particles in Escherichia coli. Biochemistry 7: 456-472. [Abs]

  25. Apirion, D. and Schlessinger, D. (1968). Mutations in ribosomal genes of Escherichia coli. Proc. of the 12th Inter. Genetic Congress. Tokyo 2: 51-52.

  26. Kwan, C.N., Apirion, D. and Schlessinger, D. (1968). Anaerobiosis induced changes in an isoleucyl-tRNA and the 50S ribosomes of Escherichia coli. Biochemistry 7: 427-433. [Abs]

  27. Apirion, D. and Schlessinger, D. (1968). Coresistance to neomycin and kanamycin by mutations in an Escherichia coli locus that affects ribosomes. J. Bacteriol. 96: 768-776. [Abs]

  28. Luzzatto, L., Apirion, D. and Schlessinger, D. (1968). Mechanism of action of streptomycin in Escherichia coli: Interruption of the ribosome cycle at the inititation of protein synthesis. Proc. Natl. Acad. Sci. Wash. 60: 873-880. [Abs]

  29. Luzzatto, L., Schlessinger, D. and Apirion, D. (1968). Escherichia coli: High resistance or dependence on streptomycin produced by the same allele. Science 161: 478-479. [Abs]

  30. Apirion, D. and Schlessinger, D. (1968). Mapping and complementation of three genes specifying 30S ribosomal components in E. coli:. J. Bacteriol. 96: 1431-1432. [Abs]

  31. Apirion, D., Schlessinger, D., Phillips, S. and Sypherd, P. (1969). Escherichia coli: Reversion from streptomycin dependence, a mutation in a specific 30S ribosomal protein. J. Mol. Biol. 43: 327-329.

  32. Luzzatto, L., Apirion, D. and Schlessinger, D. (1969). Polyribosome depletion and blockage of the ribosome cycle by streptomycin in Escherichia coli. J. Mol. Biol. 42: 315-335. [Abs]

  33. Phillips, S.L., Schlessinger, D. and Apirion, D. (1969). Mutants in Escherichia coli ribosomes: a new selection. Proc. Natl. Acad. Sci. USA 62: 772-777. [Abs]

  34. Apirion, D. and Schlessinger, D. (1969). Functional interdependence of ribosomal components of Escherichia coli. Proc. Natl. Acad. Sci. USA 63: 794-799. [Abs]

  35. Apirion, D. and Schlessinger, D. (1969). Mutations in ribosomes genes of Escherichia coli: Pleiotropy and interactions in an organelle. Japan J. Genet. 44: 1-10, Suppl. 1.

  36. Apirion, D. and Schlessinger, D. (1969). The effect of ribosome alterations on ribosome function and on expression of ribosome and non-ribosome mutations. CIBA Foundation Symposium on "Mutation as Cellular Process": 155-167.

  37. Schlessinger, D. and Apirion, D. (1969). Escherichia coli ribosomes: Recent developments. Ann. Rev. Microbiol. 23: 387-426. [Abs]

  38. Luzzatto, L., Apirion, D. and Schlessinger, D. (1969). Streptomycin action: Greater inhibition of Escherichia coli ribosome function with exogenous than with endogenous messenger ribonucleic acid. J. Bact. 99: 206-209. [Abs]

  39. Gurgo, C., Apirion, D. and Schlessinger, D. (1969). Effects of chloramphenicol and fusidic acid on polyribosome metabolism in Escherichia coli. Federation of European Biochemical Societies Letters 3: 34-36.

  40. Gurgo, D., Apirion, D. and Schlessinger, D. (1969). Polyribosome metabolism in Escherichia coli treated with chloramphenicol, neomycin, spectinomycin or tetracycline. J. Mol. Biol. 45: 205-220. [Abs]

  41. Schlessinger, D., Gurgo, C., Luzzatto, L. and Apirion, D. (1969). Polyribosome metabolism in growing and nongrowing Escherichia coli. C.S.H. Symp. Quant. Bio. 34: 231-242. [Abs]

  42. Apirion, D., Phillips, S.L. and Schlessinger, D. (1969). Approaches to the genetics of Escherichia coli ribosomes. C.S.H. Symp. Quant. Biol. 34: 117-128. [Abs]

  43. Phillips, S.L., Schlessinger, D. and Apirion, D. (1969). Temperature dependent suppression of UGA and UAA codons in a temperature sensitive mutant of Escherichia coli. C.S.H. Symp. Quant. Biol. 34: 499-503. [Abs]

  44. Kuwano, M., Kwan, C., Apirion, D. and Schlessinger, D. (1969). RNase V of Escherichia coli. I. Dependence on ribosomes and translocation. Proc. Natl. Acad. Sci. USA 64: 693-700. [Abs]

  45. Schlessinger, D. (1969). Development of some current ideas. Bacteriological Reviews 33: 445-453. [Abs] (Lilly Award Address, 1969)

  46. Kuwano, M., Kwan, C.N., Apirion, D. and Schlessinger, D. (1970). RNase V: a messenger RNase associated with E. coli ribosomes. In First Lepetit Colloquium on RNA polymerase and transcription. (Florence, November 14-16, p 222.)

  47. Kuwano, M., Schlessinger, D. and Apirion, D. (1970). RNase V of Escherichia coli. II. Requires ribosomes and is inhibited by drugs. Nature 226: 514-516. [Abs]

  48. Kuwano, M., Apirion, D. and Schlessinger, D. (1970). RNase V of Escherichia coli. IV. Exonucleolytic cleavage in the 5'-3' direction with production of 5'-nucleotide monophosphates. J. Mol. Biol. 51: 75-82. [Abs]

  49. Kuwano, M. Apirion, D. and Schlessinger, D. (1970). RNase V of Escherichia coli: III. Susceptibility of heated ribosomal RNA and stability of R17 phage RNA. Science 168: 1225-1226. [Abs]

  50. Kuwano, M. and Schlessinger, D. (1970). Binding of adenosine 3':5'-cyclic phosphate to G factor of E. coli, and its effect on GTPase, and RNase V, and protein synthesis. Proc. Natl. Acad. Sci. USA. 66: 146-152. [Abs]

  51. Kuwano, M., Apirion, D. and Schlessinger, D. (1970). Ribonuclease V of Escherichia coli. : V. Requirement-457 for ribosome translocation, but not for polypeptide formation. J. Mol. Biol. 51: 453-457. [Abs]

  52. Chou, J.Y. and Schlessinger, D. (1970). UGA nonsense suppression assayed by T4 DNA-dependent in vitro synthesis of lysozyme. Biochem. Biophys. Res. Commun. 41: 981-986.

  53. Schlessinger, D. and Apirion, D. (1971). Formation and breakdown of polyribosomes in protein synthesis. A series of advances. E.H. McConkey, ed., Marcel Dekker, Inc. pp 149-178.

  54. Kuwano, M., Schlessinger, D., Rinaldi, G., Felicetti, L. and Tocchini-Valentini, G.P. (1971). G factor mutants of Escherichia coli: map location and properties. Biochem. Biophys. Res. Commun. 42: 441-444. [Abs]

  55. Kuwano, M., Schlessinger, D. and Morse, D.E. (1971). Loss of dispensable endonuclease activity in relief of polarity of suA. Nature New Biol. 231: 214-217. [Abs]

  56. Schlessinger, D. (1971). Repertoire of genetic control of gene expression in procaryotes. Stadler Symp. Vol. 3: 25-36.

  57. Mangiarotti, G., Schlessinger, D. and Kuwano, M. (1971). Initiation of ribosome-dependent breakdown of T4-specific messenger RNA. J. Mol. Biol. 60: 441-452. [Abs]

  58. Schlessinger, D., Ohnishi, Y., Kuwano, M. and Silengo, L. (1972). Effect of 3',5'-cyclic AMP on gene expression in Escherichia coli, in Effects of Drugs on Cellular Regulatory Mechanisms. Symp. Brit. Biol. Council. Ed. by B.R. Rabin and R.B. Freedman. MacMillan, New York.

  59. Corte, G., Schlessinger, D., Longo, D. and Venkov, P. (1971). Transformation of 17S to 16S ribosomal RNA using RNase II of Escherichia coli. J. Mol. Biol. 60: 325-338. [Abs]

  60. Craig, E., Schlessinger, D. and Gurgo, C. (1972). Synthesis, no synthesis, or synthesis and degradation of ribosomal RNA in various Escherichia coli strains starved for an amino acid. J. Bact. 111: 66-72. [Abs]

  61. Gurgo, C., Craig, E., Schlessinger, D. and Afolayan, A. (1971). Polyribosome metabolism in Escherichia coli starved for an amino acid. J. Mol. Biol. 62: 525-535. [Abs]

  62. Venkov, P., Schlessinger, D. and Longo, D. (1971). Inhibition of ribonuclease II of E. coli by sodium ions, adenosine 5'-triphosphate, and transfer ribonuclease acid. J. Bact. 108: 601-603. [Abs]

  63. Schlessinger, D., Phillips, S.L. and Craig, E. (1972). Effects of some antibiotics and mutational lesions on polyribosome metabolism. In Symposium on Molecular Mechanisms of Antibiotic Action on Protein Biosynthesis and Membranes. Springer-Verlag pp 75-90.

  64. Craig, E. and Schlessinger, D. (1972). Synthesis of specific, stabilized mRNA when translocation is blocked. Genetics 70: 331-336.

  65. Medoff, G., Kobayashi, G.S., Kwan, C.N., Schlessinger, D. and Venkov, P. (1972). Potentiation of rifampicin and 5-flourocytosine as antifungal antibiotics by amphotericin B. Proc. Natl. Acad. Sci. USA 69: 196-199. [Abs]

  66. Venkov, P., Waltschewa, L. and Schlessinger, D. (1972). Polyribosome metabolism in Escherichia coli. In "Functional Units in Protein Biosynthesis". Symp. of FEBS, Springer-Verlag Vol. 23: 379-394.

  67. Schlessinger, D. (1972). The longevity and translation yield of mRNA. In "The Mechanism of Protein Biosynthesis and its regulation". Ed. L. Bosch. North Holland Publishing Co. - 441-464.

  68. Craig, E., Cremer, K. and Schlessinger, D. (1972). Metabolism of T4 messenger RNA, host messenger RNA, and ribosomal RNA in T4-infected Escherichia coli B. J. Mol. Biol. 71: 701-715. [Abs]

  69. Ohnishi, Y. and Schlessinger, D. (1972). Total breakdown of ribosomal and transfer RNA in a mutant of Escherichia coli. Nature N.B. 238: 228-231. [Abs]

  70. Ohnishi, Y., Silengo, L., Kuwano, M. and Schlessinger, D. (1972). 3',5'-cyclic adenosine monophosphate-requiring mutants of Escherichia coli. J. Bacteriol. 111: 745-749. [Abs]

  71. Caskey, T., Leder, P., Moldave, K. and Schlessinger, D. (1972). Translation: Its mechanism and control. (summary of Fogarty Conference). Science 176: 195-197. [Abs]

  72. Kwan, C.N., Medoff, G., Kobayashi, G.S., Schlessinger, D. and Raskas, H.J. (1972). Potentiation of the antifungal effects of antibiotics by amphotericin B. Antimicrob. Ag. and Chemother. 2: 161-165. [Abs]

  73. Kobayashi, G.S., Medoff, G., Schlessinger, D., Kwan, C.N. and Musser, W.E. (1972). Amphortericin B. potentiation of rifampycin as an antifungal agent against the yeast phase of Histoplasma capsulatum. Science 177: 709-710. [Abs]

  74. Schwartz, S.N., Medoff, G., Kobayashi, G.S., Kwan, C.N. and Schlessinger, D. (1972). Antifungal properties of polymyxin B and its potentiation of tetracycline as an antifungal agent. Antimicrob. Ag. and Chemother. 2: 36-40. [Abs]

  75. Silengo, L. and Schlessinger, D. (1973). Messenger RNA stability in relaxed and stringent Escherichia coli starved for methionine. J. Bact. 115: 447-449.

  76. Medoff, G., Kwan, C.N., Schlessinger, D. and Kobayashi, G.S. (1973). Permeability control in animal cells by polyenes: a possibility. Antimicrob. Ag. and Chemother. 3: 441-443. [Abs]

  77. Medoff, G., Kwan, C.N., Schlessinger, D. and Kobayashi, G.S. (1973). Potentiation of rifampicin, rifampicin analogs and tetracycline against animal cells by amphortericin B and polymyxin B1. Cancer Research 33: 1146-1149. [Abs]73218289

  78. Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1973). Polyene potentiation of antitumor agents. J. Nat. Can. Inst. 50: 1047-1050. [Abs]

  79. Nikolaev, N., Silengo, L. and Schlessinger, D. (1973). Synthesis of a large precursor to ribosomal RNA in a mutant of Escherichia coli. Proc. Natl. Acad. Sci. USA 70: 3361-3365. [Abs]

  80. Nikolaev, N., Silengo, L. and Schlessinger, D. (1973). A role of RNase III in processing of rRNA and mRNA precursors in Escherichia coli. J. Biol. Chem. 248: 7967-7969. [Abs]

  81. Glazier, K. and Schlessinger, D. (1974). Magic spot metabolism in an Eschericia coli mutant temperature sensitive in EFTs. J. Bact. 117: 1195-1200. [Abs]

  82. Cremer, K., Imamoto, F. and Schlessinger, D. (1974). Limitation of transcription by puromycin or chloramphenicol DNA-coupled systems from E. coli. Mol. Gen. Genet. 130: 183-188.

  83. Venkov, P., Hadjiolov, A.A., Battaner, E. and Schlessinger, D. (1974). Saccharomyces cerevisia: sorbitol-dependent fragile mutants. Biochem Biophys. Res. Commun. 56: 599-604. [Abs]

  84. Kotler-Brajtburg, J.K., Price, H.D., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1974). Molecular basis for the selective toxicity of amphotericin B for yeast and filipin for animal cells. Antimicrob. Ag. Chemother. 5: 377-382.

  85. Medoff, G., Valeriote, F., Lynch, R.G., Schlessinger, D. and Kobayashi, G.S. (1974). Synergistic effect of amphotericin B and 1,3-bis(2-chloroethyl)1-nitrosourea against a transplantable AKR leukemia. Cancer Res. 34: 974-978. [Abs]

  86. Kobayashi, G.S., Cheung, S.C., Schlessinger, D. and Medoff, G. (1974). Effects of rifamycin derivatives, alone and in combination with amphotericin B, against Histoplasma capsulatum. Antimicrob. Ag. Chemother. 5: 16-18. [Abs]

  87. Boguslawski, G., Schlessinger, D., Medoff, G. and Kobayashi, G.S. (1974). Ribonucleic acid polymerases of the yeast phase of Histoplasma capsulatum. J. Bact. 118: 480-485. [Abs]

  88. Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1974). Sensitivity of transformed and nontransformed cells to amphotericin B and several rifamycin derivatives. Cancer Res. 34: 823-826. [Abs]

  89. Schlessinger, D. and Medoff, G. (1974). Streptomycin, dihydrostreptomycin and the gentamicins. In The Antibiotics, ed. by F. Hahn and J.W. Corcoran. Springer-Verlag, New York. Vol. pp 535-550.

  90. Cremer, K., Silengo, L. and Schlessinger, D. (1974). Polypeptide formation and polyribosomes in E. coli treated with chloramphenicol. J. Bact. 118: 582-589. [Abs]

  91. Kwan, C.N., Gotoh, S. and Schlessinger, D. (1974). Nucleases in HeLa cell nucleoplasm and nucleoli. Biochem. Biophys. Acta 349: 428-441. [Abs]

  92. Cheung, S.C., Kobayashi, G.S., Schlessinger, D. and Medoff, G. (1974). RNA metabolism during morphogenesis in Histoplasma capsulatum. J. Gen Microbiol. 82: 301-307. [Abs]

  93. Kumar, V.K., Medoff, G., Kobayashi, G.S. and Schlessinger, D. (1974). Uptake of Escherichia coli DNA into HeLa cells enhanced by amphotericin B. Nature 250: 323-325. [Abs]

  94. Schlessinger, D. (1974). Ribosomes formation in E. coli (review chapter In Ribosomes). Cold Spring Harbor Laboratory, 393-416.

  95. Nikolaev, N., Schlessinger, D. and Wellauer, P.K. (1974). 30S pre-rRNA of E. coli and products of cleavage by RNase III: Length and molecular weight. J. Mol. Biol. 86: 741-747. [Abs]

  96. Cremer, K. and Schlessinger, D. (1974). Ca2+ ions inhibit mRNA degradation, but permit mRNA transcription and translation in deoxyribonucleic acid-coupled systems from E. coli. J. Biol. Chem. 249: 4730-4736. [Abs]

  97. Schlessinger, D. (1974). Genetic and antibiotic modification of protein synthesis. Ann. Rev. Gen. 8: 135-151. [Abs]

  98. Nikolaev, N. and Schlessinger, D. (1974). Binding of ribosomal proteins to 30S pre-rRNA of Escherichia coli. Biochemistry 13: 4272-4278. [Abs]

  99. Gotoh, S., Nikolaev, N., Battaner, E., Birge, C.H. and Schlessinger, D. (1974). Escherichia coli RNase III cleaves HeLa cell nuclear RNA. Biochem. Biophys. Res. Commun. 59: 972-978. [Abs]

  100. Schlessinger, D., Ono, M., Nikolaev, N. and Silengo, L. (1974). Accumulation of 30S preribosomal RNA in an Escherichia coli mutant treatment with chloramphenicol. Biochemistry 13: 4268-4271. [Abs]

  101. Nikolaev, N., Birge, C.H., Gotoh, S., Glazier, K. and Schlessinger, D. (1974). Primary processing of high molecular weight preribosomal RNA in Escherichia coli and HeLa cells. Brookhaven Symp. in Biology 26: 175-193.

  102. Silengo, L., Nikolaev, N., Schlessinger, D. and Imamoto, F. (1974). Stabilization of messenger RNA with polar effects in an Escherichia coli mutant. Mol. Gen. Genet. 134: 7-19. [Abs]

  103. Kotler-Brajtburg, J., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1974). Characterization of the binding of amphotericin B to Saccharomyces cerevisiae and relationship to the antifungal effects. Antimicrob. Ag. Chemother. 6: 770-776. [Abs]

  104. Imamoto, F. and Schlessinger, D. (1974). Bearing of some recent results on the mechanisms of polarity and messenger RNA stability. Mol. Gen. Genet. 135: 29-38. [Abs]

  105. Dahlberg, J.E., Nikolaev, N. and Schlessinger, D. (1974). Methylation of 30S pre-rRNA and mature rRNA. Brookhaven Symp. RNA Processing 26: 194-200. [Abs]

  106. Chaney, S.G. and Schlessinger, D. (1975). Escherichia coli mutants deficient in RNA accumulation at high temperature. Biochem. Biophys. Acta 378: 80-91. [Abs]

  107. Gupta, R.S. and Schlessinger, D. (1975). Differential modes of chemical decay for early and late lambda messenger RNA messenger RNA. J. Mol. Biol. 92: 311-318. [Abs]

  108. Nikolaev, N., Birenbaum, M. and Schlessinger, D. (1975). 30S pre-ribosomal RNA of Escherichia coli: primary and secondary processing. Biochem. Biophys. Acta. 395: 478-489. [Abs]

  109. Nikolaev, N., Glazier, D. and Schlessinger, D. (1975). Cleavage of ribonuclease III of the complex of 30S pre-ribosomal RNA and ribosomal proteins of Escherichia coli. J. Mol. Biol. 94: 301-304. [Abs]

  110. Medoff, J., Medoff, G., Goldstein, M.N., Schlessinger, D. and Kobayashi, G.S. (1975). Amphotericin B-induced sensitivity to actinomycin D in drug-resistant HeLa cells. Cancer Research 35: 2548-2552. [Abs]

  111. Cheung, S.C., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1975). Stability of amphotericin B in fungal culture media. Antimicrob. Ag. Chemother. 8: 426-428. [Abs]

  112. ibid. (1975). Response of yeast and mycelial phases of Histoplasma capsulatum to amphotericin B and actinomycin D. Antimicrob. Ag. Chemother. 8: 498-503. [Abs]

  113. Hayes, F., Vasseur, M., Nikolaev, N., Schlessinger, D., Widada, J.S., Krol, A. and Branlant, C. (1975). Structure of a 30S pre-ribosomal RNA of E. coli. FEBS Letters 56: 85-91. [Abs]

  114. Gupta, R. and Schlessinger, D. (1976). Coupling of rates of transcription, translation, and messenger RNA degradation in streptomycin-dependent mutants of Escherichia coli. J. Bact. 125: 84-93. [Abs]

  115. Nikolaev, N., Folsom, V. and Schlessinger, D. (1976). Escherichia coli mutants deficient in exoribonucleases. Biochem. Biophys. Res. Commun. 70: 920-924. [Abs]

  116. Schlessinger, D., Jacobs, K.A., Gupta, R.S., Kano, Y. and Imamoto, F. (1977). Decay of individual Escherichia coli trp mRNA molecules is sequentially ordered. J. Mol. Biol. 110: 421-439. [Abs]

  117. Jacobs, K.A. and Schlessinger, D. (1977). Escherichia coli DNA-directed ß-galactosidase synthesis in presence and absence of Ca2+. Biochemistry 16: 914-920. [Abs]

  118. Wolf, S.F. and Schlessinger, D. (1977). Nuclear metabolism of ribosomal RNA in growing methionine-limited, and ethionine-treated HeLa cells. Biochemistry 16: 2783-2990. [Abs]

  119. Saha, B.K. and Schlessinger, D. (1977). Double-stranded ribonuclease activities from HeLa cell nuclei. Biochem. Biophys. Res. Commun. 79: 1142-1149. [Abs]

  120. Kotler-Brajtburg, J.K., Medoff, G., Kobayashi, G. and Schlessinger, D. (1977). Sensitivity to amphotericin B and the cholesterol: phospholipid molar ratios of 3T3, L, BHK and HeLa cells. Biochem. Parmocol. 26: 705-710. [Abs]

  121. Kotler-Brajtburg, J., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1977). Amphotericin B and filipin effects on L and HeLa cells: dose response. Antimicrob. Ag. and Chemother. 1: 803-808. [Abs]

  122. Macmillian, R., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1977). Inhibition of isolated yeast and mycelial phase RNA polymerases of Histoplasm capsulatum by rifamycin derivatives. Sabouraudia 15: 257-261. [Abs]

  123. Maresca, B., Medoff, J., Medoff, G., Schlessinger, D. and Kobayashi, G. (1977). Regulation of dimorphism in the pathogenic fungus H. capsulatum. Nature 266: 447-448. [Abs]

  124. Macmillian, R., Kumar, B.V., Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1977). Inhibition of H. capsulatum RNA polymerases by homologous and heterologous. RNA. J. Bact. 130: 1387-1389. [Abs]

  125. Gupta, R.S., Kasai, T. and Schlessinger, D. (1977). Purification and some novel properties of Escherichia coli ribonuclease II. J. Biol. Chem. 252: 8945-8949. [Abs]

  126. Kasai, T., Gupta, R.S. and Schlessinger, D. (1977). Exoribonucleases in wild-type E. coli and ribonuclease II - deficient mutants. J. Biol. Chem. 252: 8950-8956. [Abs]

  127. Kumar, B.V., McMillian, R. Medoff, G., Schlessinger, D. and Kobayashi, G.S. (1977). Mechanisms of the inhibition by RNA of the RNA polymerases of Histoplasma capsulatum. Biochem. Biophys. Acta 478: 192-200. [Abs]

  128. Birenbaum, M., Schlessinger, D. and Hashimoto, S. (1978). RNase III cleavage of Escherichia coli rRNA precursors: fragment release and dependence on salt concentration. Biochemistry 17: 298-307. [Abs]

  129. Jacobs, K.A., Shen, V. and Schlessinger, D. (1978). Coupling of lac mRNA transcription to translation in Escherichia coli cell extracts. Proc. Natl. Acad. Sci. 75: 158-161. [Abs]

  130. Liebhaber, S.A., Wolf, S. and Schlessinger, D. (1978). Differences in rRNA metabolism of primary and SV40-transformed human fibroblasts. Cell 13: 121-127. [Abs]

  131. Liebhaber, S.A. and Schlessinger, D. (1978). Tritium-arrested human diploid fibroblasts maintain balanced RNA and protein metabolism. Exp. Cell Res. 112: 353-359.[Abs]

  132. Saha, B.K. and Schlessinger, D. (1978). Separation and characterization of two activities from HeLa cell nuclei that degrade double-stranded RNA. J. Biol. Chem. 253: 4537-4543. [Abs]

  133. Gotoh, S., Gelb, L. and Schlessinger, D. (1979). SV40-transformed human diploid cells that remain transformed throughout their limited lifespan. J. Gen. Virol. 42: 409-414. [Abs]

  134. Saha, B.K., Graham, M. and Schlessinger, D. (1979). Acid ribonuclease from HeLa cell lysosomes. J. Biol. Chem. 254: 5951-5957. [Abs]

  135. Birenbaum, M., Schlessinger, D. and Ohnishi, Y. (1980). Altered T4RNA metabolism in an RNase II-deficient mutant of Escherichia coli. J. Bact. 142: 327-330. [Abs]

  136. Nakamura, H., Kano, Y., Schlessinger, D., Imamoto, F., McPartland, A. and Somerville, R.L. (1979). Translation-uncoupled transcription of promoter-proximal DNA sequences in E. coli strains harboring mutationally-generated constitutive promoters within genes of the trp operon. Mol. Gen. Genet. 172: 127-136. [Abs]

  137. Birenbaaum, M., Shen, V., Nikolaev, N. and Schlessinger, D. (1979). Site-specific processing of Escherichia coli preribosomal RNA and preribosomes by E. coli RNase III. In Meth. Enzymol. 59: 824-837. [Abs]

  138. Schlessinger, D. (1979). Processing of ribosomal RNA transcripts in bacteria. In "Ribosomes". (Davies, J. et al., eds.) University Park Press, MD. 767-781.

  139. Kotler-Brajtburg, J., Medoff, G., Kobayashi, G.S., Boggs, S., Schlessinger, D., Pandey, R.C. and Rinehart, Jr., K.L. (1979). Classification of polyene antibiotics according to chemical structure and biological effects. Antimicrob. Ag. and Chemother. 15: 716-722.

  140. Wolf, S., Sameshima, M., Liebhaber, S.A. and Schlessinger, D. (1980). Regulation of ribosomal ribonucleic acid levels in growing 3H-arrested, and crisis-phase WI-38 human diploid fibroblasts. Biochemistry 19: 3484-3490. [Abs]

  141. Bowman, L.H., Rabin, B. and Schlessinger, D. (1981). Multiple ribosomal RNA cleavage pathways in mammalian cells. Nucleic Acids Res. 9: 4951-4966. [Abs]

  142. King, T.C., Schlessinger, D. and Milanovich, F. (1980). Laser Raman studies of RNA backbone ordering in E. coli ribosomes: Invited paper in Biophysical Discussions, "Proteins and Nucleoproteins: Structure, Dynamics and Assembly". Biophys. 32: 456-458.

  143. Saha, B.K., Sameshima, M., Sameshima, F. and Schlessinger, D. (1981). Lysosomal enzyme activities and RNA turnover rates in growing and non-growing WI-38 and HeLa cells. In Vitro 17: 816-824. [Abs]

  144. Schlessinger, D. (1980). "Bacteria". In World Book Encyclopedia. Field Publ., Chicago.

  145. Bhaduri, S., Kasai, T., Schlessinger, D. and Raskas, H.J. (1980). pMB9 plasmids bearing the S. typhimurium his operon and gnd gene. Gene 8: 239-253. [Abs]

  146. Hirschel, B.J., Shen, V. and Schlessinger, D. (1980). Lactose operon transcription from wild-type and L8-UV5 lac promoters in Escherichia coli treated with chloramphenicol. J. Bact. 143: 1534-1537. [Abs]

  147. King, T.C., Schlessinger, D. and Krogstad, D.J. (1981). The assessment of antimicrobial combinations. Rev. Inf. Dis. 3: 627-633. [Abs]

  148. Sameshima, M., Liebhaber, S.A. and Schlessinger, D. (1981). Dual pathways for RNA turnover in WI-38 but not in I-cell human diploid fibroblasts. Mol. Cell Biol. 1: 75-81. [Abs]

  149. King, T.C., Rucinsky, T. and Schlessinger, D. (1981). Escherichia coli ribosome unfolding in low Mg2+ solutions observed by Laser Raman spectroscopy and electron microscopy. Nucl. Acids. Res. 9: 647-661. [Abs]

  150. Shen, V., Cynamon, M. Daugherty, B., Kung, H. and Schlessinger, D. (1981). Functional inactivation of Lac-peptide mRNA by a factor that purifies with E. coli RNase IV. J. Biol. Chem. 256: 1896-1902. [Abs]

  151. Fine, J.M. et al. (1981). Proposal for nomenclature of hereditary albumin variants. La Ricerca 11: 285.

  152. Sameshima, M. and Schlessinger, D. (1981). Effects of growth state and 3H labeling level on RNA turnover in WI-38 fibroblasts and HeLa cells. Radiat. Res. 8: 333-342. [Abs]

  153. Graham, M.Y., Tal, M. and Schlessinger, D. (1982). Lac transcription in E. coli cells treated with chloramphenicol. J. Bact. 151: 251-261. [Abs]

  154. Shen, V., Imamoto, F. and Schlessinger, D. (1982). RNase III cleavage of Escherichia coli b-galactosidase and tryptophan operon mRNA. J. Bact. 150: 1489-1494. [Abs]

  155. Shen, V. and Schlessinger, D. (1982). RNases I, II and IV of Escherichia coli. In The Enzymes, ed. P. Boyer. Acad. Press. Vol. XV pp 501-515.

  156. Schlessinger, D. (1982). B. subtilis versus E. coli. Cell 31: 499-500 (Book Review).

  157. Bowman, L.H., Goldman, W.E., Goldberg, G.I., Herbert, M.B. and Schlessinger, D. (1983). Location of the initial cleavage sites in mouse pre-rRNA. Mol. Cell Biol. 3: 1501-1510. [Abs]

  158. Goldman, W., Goldberg, G., Bowman, L., Steinmetz, D. and Schlessinger, D. (1983). Mouse ribosomal DNA: sequences and evolutionary analysis of spacer and mature RNA regions. Mol. Cell Biol. 3: 1488-1500. [Abs]

  159. Klein, B.K., King, T.C. and Schlessinger, D. (1983). Structure of partially denatured E. coli 23S rRNA determined by electron microscopy. J. Mol. Biol. 168: 309-330. [Abs]

  160. D'Urso, M., Mareni, C., Toniolo, D., Piscopo, M., Schlessinger, D. and Luzzatto, L. (1983). Regulation of glucose-6-phosphate dehydrogenase expression in CHO-human fibroblast somatic cell hybrids. Somatic Cell Genetics 9: 429-443. [Abs]

  161. Schlessinger, D., Graham, M.Y., Shen, V. and Tal, M. (1983). Coupling of lac mRNA formation and decay to translation. Microbiology 83: 82-85.

  162. King, T.C. and Schlessinger, D. (1983). S1 nuclease mapping analysis of ribosomal RNA processing in wild-type and processing deficient Escherichia coli. J. Biol. Chem. 258: 12034-12042. [Abs]

  163. Saha, B.K., Strelow, S. and Schlessinger, D. (1983). Electrophoretic elution of nucleic acids from acrylamide and agarose gels. J. Biochem. Biophys. Meth. 7: 277-284. [Abs]

  164. Brajtburg, J., Elberg, S., Bolard, J., Kobayashi, G.S., Levy, R.A., Ostlund, R.E., Schlessinger, D. and Medoff, G. (1984). Interaction of plasma proteins and lipoproteins with Amphortericin B. J. Inf. Dis. 149: 986-997. [Abs]

  165. King, T.C., Sirdeshmukh, R. and Schlessinger, D. (1984). RNase III cleavage is obligate for maturation but not for function of E. coli pre-23S rRNA. Proc. Natl. Acad. Sci. USA 81: 185-188. [Abs]

  166. Klein, B.K., Forman, P., Shiomi, Y. and Schlessinger, D. (1984). Electron microscopy of secondary structure in 16S partially denatured E. coli 16S rRNA and 30S subunits. Biochem. 23: 3927-3933. [Abs]

  167. Brajtburg, J., Elberg, S., Schwartz, D.R., Vertut-Croquin, A., Schlessinger, D., Kobayashi, G.S.and Medoff, G. (1985). Involvement of oxidative damage in erythrocyte lysis induced by Amphotericin B. Antimicrob. Ag. Chemother. 27: 172-176. [Abs]

  168. Brajtburg, J., Elberg, S., Medoff, J., Kobayashi, G.S., Schlessinger, D. and Medoff, G. (1984). Stimulatory, permeabilizing and toxic effects of Amphotericin B on L cells. Antimicrob. Ag. Chemother. 26: 892-897. [Abs]

  169. Klein, B., Romero, J. and Schlessinger, D. (1985). Electron Microscopy of secondary structure in bacillus stearothermophilus ribosomal RNA compared to Escherichia coli. J. Bacteriol. 161: 981-988. [Abs]

  170. Klein, B.K., Staden, A. and Schlessinger, D. (1985). Alternative conformations in Escherichia coli 16S rRNA. Proc. Natl. Acad. Sci. USA 82: 3539-3542. [Abs]

  171. Klein, B.K., Staden, A. and Schlessinger, D. (1985). Electron microscopy of secondary structure in partially denatured precursor and mature E. coli 16S and 23S rRNA. J. Biol. Chem. 260: 8114-8120. [Abs]

  172. Bolla, R., Braaten, D., Shiomi, Y., Herbert B. and Schlessinger, D. (1985). Localization of specific DNA spacer sequences to the mouse L cell nucleolar matrix. Mol. Cell Biol. 5: 1287-1294. [Abs]

  173. Sirdeshmukh, R., Krych, M. and Schlessinger, D. (1985). Escherichia coli 23S ribosomal RNA truncated as its 5' terminus. Nucleic Acids Res. 13: 1185-1192. [Abs]

  174. Sirdeshmukh, R. and Schlessinger, D. (1985). Ordered processing of Escherichia coli 23S rRNA in vitro. Nucleic Acids Res. 13: 5041-5054. [Abs]

  175. Schlessinger, D., Bolla, I, Sirdeshmukh and Thomas J.R. (1985). Spacers and processing of large rRNAs in E. coli and mouse cells. BioEssays 3: 14-18. [Abs]

  176. Thomas, J.R., Bolla, R.I., Rumbyrt, J.S. and Schlessinger, D. (1985). DNase I-resistant non-transcribed spacer segments of mouse ribosomal DNA contain poly (dG-dT). poly(dA-dC). Proc. Natl. Acad. Sci. USA 82: 7595-7598. [Abs]

  177. Sirdeshmukh, R. and Schlessinger, D. (1985). Why is processing of 23S ribosomal RNA in Escherichia coli not obligate for its function? J. Mol. Biol. 186: 669-672. [Abs]

  178. Shiomi, Y., Powers, J., Bolla, R.I., Van Nguyen, T. and Schlessinger, D. (1986). Proteins and RNA in mouse L cell core nucleoli and nucleolar matrix. Biochemistry 25: [Abs]

  179. Medoff, G., Sacco, M., Maresca, B. and Schlessinger, D. (1986). Irreversible block of the mycelial-to-yeast phase transition of histoplasma capsulatum. Science 231: 476-479. [Abs]

  180. King, T.C., Sirdeshmukh, R. and Schlessinger, D. (1986). Nucleolytic processing of RNA transcripts in procaryotes. Microbiol. Rev. 50: 428-451. [Abs]

  181. Schlessinger, D., Thomas, J.R., Krych, M., Sirdeshumkh, R. and Little, R.D. (1986). Ribosomal RNA processing in Escherichia coli and cultured mammalian cells. Biochem. Soc. Trans. 14: 811-814. [Abs]

  182. Braaten, D.C., Thomas, J.R., Little, R.D., Dickson, K.R., Goldberg, I., Schlessinger, D., Ciccodicola, A. and D'Urso, M. (1988). Locations and contexts of sequences that hybridize to poly (dG-dT).(dC-dA) in mammalian ribosomal DNAs and two X-linked genes. Nucleic Acids Res. 16: 865-881. [Abs]

  183. Krych, M., Sirdeshmukh, R., Gourse, R. and Schlessinger, D. (1987). Processing of Escherichia coli 16S rRNA with bacteriophage lambda leader sequences. J. Bact. 169: 5523-5529. [Abs]

  184. Schlessinger, D. (1988). Failure of aminoglycoside antibiotics to kill anaerobic, low pH, and resistant cultures. Clin. Microbiol. Rev. 1: 54-59. [Abs]

  185. Raziuddin, Little, R.D., Labella, T. and Schlessinger, D. (1989). Transcription and processing of RNA from mouse ribosomal DNA transfected into hamster cells. Mol. Cell. Biol. 9: 1667-1671. [Abs]

  186. Srivastava, A.K. and Schlessinger, D. (1989). Escherichia coli 16S rRNA 3'-end formation requires a distal transfer RNA sequence at a proper distance. EMBO J. 8: 3159-3166. [Abs]

  187. Little, R.D., Porta, G., Carle, G., Schlessinger, D. and D'Urso, M. (1989). Yeast artificial chromosomes with 200 to 800-kilobase inserts of human DNA containing HLA, Vk, 5S and Xq24-Xq28 sequences. Proc. Natl. Acad. Sci. USA 86: 1598-1602. [Abs]

  188. Brownstein, B., Silverman, G.A., Little, R.D., Burke, D.T., Korsmeyer, S.J., Schlessinger, D. and Olson, M.V. (1989). Isolation of single-copy human genes from a library of yeast artificial-chromosome clones. Science 244: 1348-1351. [Abs]

  189. Labella, T. and Schlessinger, D. (1989). Complete human rDNA repeat units isolated in yeast artificial chromosomes. Genomics 5: 752-760. [Abs]

  190. Srivastava, A.K., and Schlessinger, D. (1989). Preparation of extracts and assay of rRNA maturation in E. coli. In "RNA Processing, Meth. Enzymol". Dahlberg, J.E. and Abelson, J.N., eds. Academic Press, Inc. 181:part B. pp. 355-366.

  191. Srivastava, A.K. and Schlessinger, D. (1989). Ribosomal RNA processing in E. coli. In "Structure Function and Evolution of Ribosome". W. Hill, ed. pp. 426-434.

  192. Wada, M., Little, R.D., Abidi, F., Porta, G., Labella, T., Cooper, T., Della Valle, G., D'Urso, M. and Schlessinger, D. (1990). Human Xq24-Xq28: Approaches to mapping with yeast artifical chromosomes. Amer. J. Human Genet. 46: 95-106. [Abs]

  193. Srivastava, A.K., and Schlessinger, D. (1989). Processing pathway of E. coli 16S precursor rRNA. Nucleic Acids Res. 17: 1649-1663. [Abs]

  194. Srivastava, A.K. and Schlessinger, D. (1988). Coregulation of processing and translation: Mature 5' termini of E. coli 23S rRNA form in polysomes. Proc. Natl. Acad. Sci. USA. 85: 7144-7148. [Abs]

  195. Dickson, K.R., Braaten, D.C. and Schlessinger, D. (1989). Human ribosomal DNA: conserved sequence elements in a 4.3-kb region downstream from the transcription unit. Gene 84: 197-200. [Abs]

  196. Chen, E.Y., Cheng, A., Lee, A., Kuang, W-J., Hillier, L., Green, P., Schlessinger, D., Ciccodicola, A. and D'Urso, M. (1991). Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome (YAC). Genomics 10: 792-800. [Abs]

  197. D'Urso, M., Zucchi, I., Ciccodicola, A., Palmieri, G., Abidi, F.E. and Schlessinger, D. (1990). Human glucose-6-phosphate dehydrogenase gene carried on a yeast artificial chromosome encodes active enzyme in monkey cells. Genomics 7: 531-534. [Abs]

  198. Srivastava, A.K. and Schlessinger, D. (1990). Mechanism and regulation of bacterial ribosomal RNA processing. Ann. Rev. Microbiol. 44: 105-129. [Abs]

  199. Abidi, F.E., Wada, M., Little, R.D. and Schlessinger, D. (1990). Yeast artificial chromosomes containing human Xq24-28 DNA: Library construction and representation of probe sequences. Genomics 7: 363-376. [Abs]

  200. Schaechter, M., Medoff, G. and Schlessinger, D. (1989). "Mechanisms of Microbial Disease". Schaechter, et al. eds., Williams & Wilkins, Baltimore, Md.

  201. Eliceiri, B., Labella, T., Hagino, Y., Srivastava, A., Pilia, G., Palmieri, G., D'Urso, M. and Schlessinger, D. (1991). Stable integration and expression in mouse cells of yeast artificial chromosomes harboring human genes. Proc. Natl. Acad. Sci. USA 88: 2179-2183. [Abs]

  202. Montanaro, V., Casamassimi, A., D'Urso, M., Yoon, J-Y., Freije, W., Schlessinger, D., Muenke, M., Nussbaum, R.L., Saccone, S., Maugeri, S., Santoro, A.M., Motta, S., and Della Valle, G. (1991). In situ hybridization to cytogenetic bands of yeast artificial chromosomes covering 50% of human Xq-24-Xq28 DNA. Amer. J. Human Genet. 48: 183-194. [Abs]

  203. Schlessinger, D. (1990). Yeast artificial chromosomes: Tools for mapping and analysis of complex genomes. Trends in Genetics 6: 248-255. [Abs]

  204. Srivastava, A.K. and Schlessinger D. (1990). Structure and organization of ribosomal DNA. Biochimie 73: 631-638. [Abs]

  205. Srivastava, A.K. and Schlessinger D. (1991). Vectors for inserting selectable markers in vector arms and human DNA inserts of yeast artificial chromosomes (YACs). Gene 103: 53-59. [Abs]

  206. Huxley, C., Hagino, Y., Schlessinger, D., and Olson, M. (1991). The human HPRT gene on a yeast artificial chromosome is functional when transferred to mouse cells by cell fusion. Genomics 9: 742-750. [Abs]

  207. Little, R.D., Pilia, G., Johnson, S., Zucchi, I., D'Urso, M., and Schlessinger, D. (1992). Yeast artificial chromosomes spanning 8 Mb and 10-15 centimorgans of human cytogenetic band Xq26. PNAS 89: 177-181. [Abs]

  208. Zucchi, I. and Schlessinger, D. (1992). Distribution of moderately repetitive sequences pTR5 and LF1 in Xq24-q28 human DNA, and their use to assemble YAC contigs. Genomics 12: 264-275. [Abs]

  209. Schlessinger, D., Little, R.D., Freije, D., Abidi, F., Zucchi, I., Porta, G., Pilia, G., Nagaraja, R., Johnson, S.K., Yoon, J.Y., Srivastava, A., Kere, J. Palmieri, G., Ciccodicola, A., Montanaro, V., Romano, G., Casamassimi, A. and D'Urso, M. (1991). Yeast artificial chromosome-based genome mapping: Some lessons from Xq24-q28. Genomics 11: 783-793. [Abs]

  210. Yu, S., Pritchard, M., Kremer, E., Lynch, M., Nancarrow, J., Baker, E., Holman, K., Mulley, J.C., Warren, S.T., Schlessinger, D., Sutherland, G.R., and Richards, R.I. (1991). Fragile X genotype characterized by an unstable region of DNA. Science 252: 1179-1181. [Abs]

  211. Freije, D. and Schlessinger, D. (1992). A 1.6 Mb contig of yeast artificial chromosomes around the human Factor VIII gene reveals a locus homologous to DXYS64 as well as several duplicated sequences. Am. J. Hum. Genet. 51: 66-80. [Abs]

  212. Heitz, D., Rousseau, F., Devys, D., Saccone, E., Abderrrahim, H., Lepaslier, D. Cohen, D.,Vincent, A., Toniolo, D., Della Valle, G., Johnson, S., Schlessinger, D., Oberle, I., and Mandel, J.L. (1991). Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island. Science 251: 1236-1239. [Abs]

  213. Oberle, I., Rousseau, F., Heitz, D., Kretz, C., Debys, D., Hanauer, A., Boue, J., Bertheas, M.F., and Mandel, J.L. (1991). Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252: 1097-1102.

  214. Kremer, E.J., Pritchard, M., Lynch, M., Yu, S., Holman, K., Baker, E., Warren, S.T., Schlessinger, D., Sutherland, G.R., and Richards, R.J. (1991). Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n.. Science 252: 1711-1714. [Abs]

  215. Kremer, E.J., Yu, S., Pritchard, M., Nagaraja, R., Heitz, D., Lynch, M., Baker, E., Hyland, V.J., Little, R.D., Wada, M., Toniolo, D., Vincent, A., Rousseau, F., Schlessinger, D., Sutherland, G.R. and Richards, I. (1991). Isolation of a human DNA sequence which spans the fragile X. Am. J. Hum. Genet. 49: 656-661.

  216. Hirst, M.C., Rack, K., Nakahori, Y., Roche, A., Bell, M.V., Flynn, G., Christadoulou, Z., MacKinnon, R.N., Francis, M., Littler, A.J., Anand, R., Poustka, A-M., Lehrach, H., Schlessinger, D., D'Urso, M., Buckle, V.J. and Davies, K.E. (1991). A YAC contig across the fragile X site defines the region of fragi`lity. Nucleic Acids Res. 19: 3283-3288.

  217. Schlessinger, D. and Kere, J. YAC-based mapping of genome structure, function, and evolution. (1992). Genome Analysis, Cold Spring Harbor Press, Cold Spring Harbor Laboratory, Long Island, NY, Vol. 4: 131-159.

  218. Mazzarella, R., Montanaro, V., Kere, J., Reinbold, R., Ciccodicola, A., D'Urso, M. and Schlessinger, D. (1992). Conserved sequence-tagged sites (STSs): a phylogenetic approach to genome mapping. Proc. Natl. Acad. Sci. USA 89: 3681-3685. [Abs]

  219. Palmieri, G., Capra, V., Romano, G., D'Urso, M., Johnson, S., Schlessinger, D., Morris, P., Hopwood, J., Di Natale, P., Gatti, R. and Ballabio, A. (1992). The iduronate sulfatase gene: isolation of a 1.2-Mb YAC contig spanning the entire gene and identification of heterogeneous deletions in patients with Hunter Syndrome. Genomics 12: 52-57. [Abs]

  220. Kere, J., Nagaraja, R., Mumm, S., Ciccodicola, A., D'Urso, M. and Schlessinger, D. (1992). Mapping human chromosomes by walking with sequence-tagged sites from end-fragments of yeast artificial chromosome inserts. Genomics 14: 241-248. [Abs]

  221. Pilia, G., Little, R.D., Aissani, B., Bernardi, G., and Schlessinger, D. (1993). Isochores and CpG islands in YAC contigs in human Xq26.1-qter. Genomics 17: 456-462. [Abs]

  222. Nakashima, T., Sekiguchi, T., Sunamoto, H., Yura, K., Tomoda, S., Kere, J., Schlessinger, D. and Nishimoto, T. (1994). Structure of the human CCG1 gene: relationship between the exons/introns and functional domain/modules of the protein. Gene 141: 193-200. [Abs]

  223. Kere, J., Grzeschik, K-H., Limon, J., Gremaud, M., Schlessinger, D. and de la Chapelle, A. (1993). Anhidrotic ectodermal dysplasia gene region cloned in yeast artificial chromosomes. Genomics 16: 305-310. [Abs]

  224. Ciccodicola, A., Cinti, C., Esposito, T., Campanile, C., Miano, M.G., Maraldi, N.M., Vitale, M., Kere, J., Schlessinger, D., D'Urso, M. (1994). Sequence-tagged Sites (STSs) from YAC insert ends and X specific flow-sorted chromosomes.Mammalian Genome 5: 511-514.

  225. Zollo, M., D'Urso, M., Schlessinger, D. and Chen, E.Y. (1993). Sequence of mouse glucose 6-phosphate dehydrogenase cDNA. DNA Seq. 3: 319-322. [Abs]

  226. Mandel, J-L., Monaco, A.P., Nelson, D., Schlessinger, D. and Willard, H. (1992). Genome Analysis and the human X chromosome. Science 258: 103-109. [Abs]

  227. Fujita, R., Sirugo, G., Duclos, F., Abderrahim, H., Le Paslier, D., Cohen, D., Brownstein, B.H., Schlessinger, D., Mandel J-L. and Koenig, M. (1992). A 530 kb YAC contig tightly linked to the Friedreich ataxia locus contains five CpG clusters and a new highly polymorphic microsatellite. Hum. Genet. 89: 531-538. [Abs]

  228. Lengauer, C., Speicher, M.R., Popp, S., Jauch, A., Taniwaki, M., Nagaraja, R., Riethman, H.C., Donis-Keller, H., D'Urso, M., Schlessinger, D. and Cremer, T. (1993). Chromosomal bar codes produced by multicolor fluorescence in situ hybridization with multiple YAC clones and whole chromosome painting probes. Hum. Molec. Genet. 2: 505-512. [Abs]

  229. Porta, G., Zucchi, I., Hillier, L., Green, P., Nowotny, V., D'Urso, M. and Schlessinger, D. (1993). Alu and L1 sequence distribution in Xq24-q28, and their comparative utility in YAC contig assembly and verification. Genomics 16: 417-425. [Abs]

  230. Palmieri, G., Romano, G., Casamassimi, A., D'Urso, M., Little, R.D., Abidi, F.E., Schlessinger, D., Lagerstrom, M., Malmgren, H., Steen-Bondeson, M.-L., Pettersson, U., Landegren, U. (1993). 1.5-Mb YAC contig in Xq28 formatted with sequence-tagged sites and including a region unstable in the clones. Genomics 16: 586-592. [Abs]

  231. Weber, C., Oudet, C., Johnson, S., Pilia, G., Schlessinger, D., Hanauer, A. (1993). Dinucleotide repeat polymorphism close to IDS gene in Xq27.3-q28 (DXS1113). Hum. Molec. Genet. 2: 612-612. [Abs]

  232. Weber, C., Oudet, C., Johnson, S., Pilia, G., Schlessinger, D., Hanauer, A. (1993). Dinucleotide repeat polymorphism at Xq26.1 (DXS1114). Hum. Molec. Genet. 2: 612-612. [Abs]

  233. Srivastava, A. K., Hagino, Y., and Schlessinger, D. (1993). Ribosomal DNA clusters in pulsed-field gel electrophoretic analysis of human acrocentric chromosomes. Mammalian Genome 4: 445-450. [Abs]

  234. Wu, B-L., Milunsky, A., Nelson, D., Schmeckpepper, B., Porta, G., Schlessinger, D., Skare, J. (1993). High-resolution mapping of probes near the X-linked lymphoproliferative disease (XLP) locus. Genomics 17: 163-170. [Abs]

  235. Chen, E.Y., Schlessinger, D., and Kere, J. (1993) Ordered shotgun sequencing, a strategy for integrated mapping and sequencing of YAC clones. Genomics 17: 651-656. [Abs]

  236. Kohno, K., Wada, M., Schlessinger, D., D'Urso, M., Tanabe, S., Oshiro, T. and Imamoto, F. (1994). Stability of YACs containing ribosomal or RCP/GCP locus DNA in wild-type S. cerevisiae and RAD mutant strains. DNA Research 1: 191-199. [Abs]

  237. Schlessinger, D., Mandel, J-L., Monaco, A.P., Nelson, D.L., and Willard, H.F. (Eds). Report of the Fourth International Workshop on Human X Chromosome Mapping, St. Louis, MO (1993). Cyto. and Cell Genet. 64: 148-194. [Abs]

  238. D'Esposito, M., Pilia, G., and Schlessinger, D. (1994). BLOCK-based PCR markers to find gene family members in human and comparative genome analysis. Human Molecular Genetics 200: 735-740. [Abs]

  239. Wada, M., Ihara, Y., Tatsuka, M., Mitsui, H., Kohno, K., Kuwano, M. and Schlessinger, D. (1994). HPRT YAC transfer into human cells by four methods and an involvement of homologous recombination. BBRC 200: 1693-1700. [Abs]

  240. Srivastava, A.K., Featherstone, T., Wein, K. and Schlessinger, D. (1995). YAC contigs mapping the human COL4A5 and COL4A6 genes and DXS118 within Xq21.3-q22. Genomics 26: 502-509. [Abs]

  241. Willard, H.F., Cremers, F., Mandel, J-L., Monaco, A.P., Nelson, D.L. and Schlessinger, D., (Eds). Report and abstracts of the Fifth International Workshop on Human X Chromosome Mapping, Heidelberg, Germany (1994). Cyto. and Cell Genet. 67: 295-358. [Abs]

  242. Wada, M., Kohno, K., Kano, Y., Mitsui, H., Kuwano, M., Schlessinger, D. and Imamoto, F. (1994). Increased retention of small chromosomes in a novel yeast mutant. J. Biochem. 116: 694-696. [Abs]

  243. D'Esposito, M., Mazzarella, R., Pengue, G., Jones, C., D'Urso, M. and Schlessinger, D. (1994). PCR-based immortalization and screening of hierarchical pools of cDNAs. Nucl. Acids Res. 22: 4806-4809. [Abs]

  244. Palmieri, G., Romano, G., Ciccodicola, A., Casamassimi, A., Campanile, C., Esposito, T., Cappa, V., Lania, A., Johnson, S., Reinbold, R., Poustka, A., Schlessinger, D., and D'Urso, M. (1995). YAC contig organization and CpG island analysis in Xq28. Genomics 24: 149-158.

  245. Pilia, G., Porta, G., Padayachee, M., Malcolm, S., Zucchi, I., Villa, A., Macchi, P., Vezzoni, P. and Schlessinger, D. (1994). Human CD40L gene maps between DXS144E and DXS300 in Xq26. Genomics 22: 249-251. [Abs]

  246. Wada, M., Abe, K., Okumura, K., Taguchi, H., Kohno, K., Imamoto, F., Schlessinger, D. and Kuwano, M. (1994). Chimeric YACs were generated at unreduced rates in conditions that suppress coligation. Nucl. Acids Res. 22: 1651-1654. [Abs]

  247. Nagaraja, R., Kere, J., MacMillan, S., Masisi, M.W.J., Johnson, D., Halley, G., Molini, B.A., Wein, K., Trusgnich, M., Ebel, B., Brownstein, B.H., Railey, B. and Schlessinger, D. (1994). Characterization of four human YAC libraries for clone size, chimerism, and X chromosome sequence representation. Nucl. Acids Res. 22: 3406-3411.

  248. Chen, E.Y., D'Urso, M., and Schlessinger, D. (1994). Functional mapping of the human genome by cDNA localization versus sequencing. BioEssays 16: 693-698. [Abs]

  249. Nelson, D.L., Ballabio, A., Cremers, F., Monaco, A.P. and Schlessinger, D. (Eds) (1995). Report of the Sixth International Workshop on X Chromosome Mapping. Banff, Alberta, Canada. Cyto. Cell Genet. 71: 307-342.

  250. Mazzarella, R., Ciccodicola, A., Esposito, T., Arcucci, A., Migliaccio, C., Jones, C., Schlessinger, D., D'Urso, M. and D'Esposito, M. (1995). Human protein kinase C Iota gene (PRKCI) is closely linked to the BTK gene in Xq21.3. Genomics 26: 629-631. [Abs]

  251. Alitalo, T., Francis, F., Kere, J., Lehrach, H., Schlessinger, D. and Willard, H.F. (1995). A 6-Mb YAC contig in Xp22.1-p22.2 spanning the DXS69E, XE59, GLRA2, PIGA, GRPR, CALB3 and PHKA2 genes. Genomics 25: 691-700. [Abs]

  252. Kohno, K., Wada, M., Kusaba, H., Sato, S., Asakuno, K., Kubo, T., Okumura, K., Green, E.D., Schlessinger, D., Kuwano, M. (1995). Functional expression and amplification of yeast artificial chromosome (YAC)-human multidrug resistance genes in mouse cells. Genome Res. 5: 245-258.

  253. Miller, A.P., Gustashaw, K., Wolff, D.J., Rider, S.HJ., Monaco, A.P., Eble, B., Schlessinger, D., Gorski, J.L., van Ommen, G-J., Weissenbach, J. and Willard, H.F. (1995). Three genes that escape X chromosome inactivation are clustered within a 6 Mb YAC contig and STS map in Xp11.21-p11.22. Hum. Mol. Genet. 4: 731-739. [Abs]

  254. Schlessinger, D. (1995) Genome sequencing projects. Nature Medicine 1: 866-868. [Abs]

  255. Srivastava, A.K., Montonen, O., Saarialho-Kere, U., Chen, E.Y., Baybayan, P., Pispa, J., Limon, J., Schlessinger, D. and Kere, J. (1995). Fine mapping of the EDA gene: a translocation breakpoint is associated with a CpG island that is transcribed. Am. J. Hum. Genet. 58: 126-132. [Abs]

  256. Zollo, M., Mazzarella, R., Bione, S., Toniolo, D., Schlessinger, D., D'Urso, M. and Chen, E.Y. (1995). Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28. DNA Seq. 6: 1-11. [Abs]

  257. Kusaba, H., Kohno, K., Asakuno, K., Kuwano, M., Okumura, K., Green, E.D., Schlessinger, D. and Wada, M. (1995). Functional expression of yeast artificial chromosome human multidrug resistance genes in mouse cells. Genome Res. 5: 245-258. [Abs]

  258. Hoovers, J.M.N., Kalikin, L.M., Johnson, L.A., Alders, M., Redeker, B., Law, D.J., Bliek, J., Steenman, M., Benedict, M., Wiegant, J., Lengauer, C., Taillon-miller, P., Schlessinger, D., Edwards, M.C., Elledge, S.J., Ivens, A., Westerveld, A., Little, P., Mannens, M., and Feinberg, A.P. (1995). Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome: rearrangement breakpoints and subchromosomal transferable fragments. Proc. Natl. Acad. Sci. USA 92: 12456-12460. [Abs]

  259. Ferrero, G.B., Franco, B., Roth, E.J., Firulli, B.A., Borsani, G., Delmas-Mata, J., Weissenbach, J., Halley, G., Schlessinger, D., Chinault, A.C., Zoghbi, H.Y., Nelson, D.L. and Ballabio, A. (1995). An integrated physical and genetic map of a 35 Mb region on chromosome Xq22.3-Xp21.3. Human Molec. Genet. 4: 1821-1827. [Abs]

  260. Trump, D., Pilia, G., Dixon, P.H., Wooding, C., Thakrar, R., Leigh, S.E.A., Nagaraja, R., Whyte, M.P., Schlessinger, D. and Thakker, R.V. (1996). Construction of a YAC contig and an STS map spanning 3.6 megabase pairs in Xp22.1.Human Genet. 97: 60-68. [Abs]

  261. Pilia, G., Hughes-Benzie, R.M., MacKenzie, A., Baybayan, P., Chen, E.Y., Huber, R., Neri, G., Cao, A., Forabosco, A. and Schlessinger, D. (1996). Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nature Genetics 12: 241-247. [Abs]

  262. Torigoe, K., Sato, S., Kusaba, H., Kohno, K., Kuwano, M., Okumura, K., Green, E.D., Tsui, L-C., Scherer, S.W., Schlessinger, D. and Wada, M. (1996). A YAC-based contig of 1.5 Mb spanning the human multidrug resistance gene region and delineating the amplification unit in three human multidrug-resistant cell lines. Genome Research 5: 233-244. [Abs]

  263. Gedeon, A.K., Kozman, H.M., Robinson, H., Pilia, G., Schlessinger, D., Turner, G., Mulley, J.C. (1996). Refinement of the background genetic map of Xq26-q27 and gene localisation for Börjeson-Forssman-Lehmann Syndrome. Amer. J. Medical Genet. 64: 63-68. [Abs]

  264. Pilia, G., MacMillan, S., Nagaraja, R., Mumm, S., Weissenbach, J. and Schlessinger, D. (1996). YAC/STS map of 9 Mb of Xq26 at 100 kb resolution, localizing 6 ESTs, 5 genes, and 32 genetic markers. Genomics 34: 55-62. [Abs]

  265. Zucchi, I., Mumm, S., Pilia, G., MacMillan, S., Reinbold, R., Susani, L., Weissenbach, J. and Schlessinger, D. (1996). YAC/STS map across 12 Mb of Xq27 at 25 kb resolution, merging Xq26-qter. Genomics 34: 42-54. [Abs]

  266. Boycott, K.M., Halley, G.R., Schlessinger, D. and Bech-Hansen, N.T. (1996). A 2-megabase physical contig incorporating 43 DNA markers on the human X chromosome at p11.23-p11.22 from ZNF21 to DXS255 Genomics 33: 488-497. [Abs]

  267. Chen, E.Y., Zollo, M., Mazzarella, R., Ciccodicola, A., Chen, C., Zuo, L., Heiner, C., Burough, F., Repetto, M., Schlessinger, D. and D'Urso, M. (1996). Long range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. Human Molec. Genet. 5: 659-668. [Abs]

  268. Hughes-Benzie, R.M., Pilia, G., Xuan, J.Y., Hunter, A.G.W., Chen, E., Golabi, M., Hurst, J., Kobori, J., Marymee, K., Pagon, R.A., Punnett, H.H., Schelley, S., Tolmie, J.L., Wohlferd, M.M., Grossman, T., Schlessinger, D., MacKenzie, A.E. (1996). Simpson-Golabi-Behmel syndrome: Genotype/phenotype analysis of 18 affected males from 7 unrelated families. Am. J. Med. Genet. 66(2): 227-234. [Abs]

  269. D'Esposito, M., Ciccodicola, A., Gianfrancesco, F., Esposito, T., Flagiello, L., Mazzarella, R., Schlessinger, D., and D'Urso, M. (1996). A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation. Nature Genetics 13: 227-229. [Abs]

  270. Kere, J., Srivastava, A.K., Montonen, O., Zonana, J., Thomas, N., Ferguson, B., Munoz, F., Morgan, D., Clarke, A., Baybayan, P., Chen, E., Ezer, S., Saarialho-Kere, U., de la Chapell, A. and Schlessinger, D. (1996). X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nature Genetics 13: 379-380. [Abs]

  271. Chen, CN., Su, Y., Baybayan, P., Siruno, A., Nagaraja, R., Mazzarella, R., Schlessinger, D., and Chen, E. (1996). Ordered shotgun sequencing of a 135 kb Xq25 YAC containing ANT-2 and four possible genes, including three confirmed by EST matches. Nucl. Acids Res. 24: 4034-4041. [Abs]

  272. Lamartine, J. Nichols, KE. Yin, L. Krainer, M. Heitzmann, F. Bernard, A. Gaudi, S. Lenoir, G.M. Sullivan, J.L. Ikeda, J.E. Porta, G. Schlessinger, D. Romeo, G. Haber, D.A. Sylla, B.S. Harkin, D.P. (1996). Physical map and cosmid contig encompassing a new interstitial deletion of the X-linked lymphoproliferative syndrome region. Eur. J. Human Genet. 4: 342-351. [Abs]

  273. Schlessinger, D. (1996). Un nuovo rinascimento in microbiologia. Bollettino di Microbiologia e Indagini di Laboratorio news 2: 5-6.

  274. Gianfrancesco, F., Esposito, T., Ruini, L., Houlgatte, R., Nagaraja, R., D'Esposito, M., Rocchi, M., Auffray, C., Schlessinger, D., D'Urso, M. and Forabosco, A. (1997). Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome. Gene. 187: 179-184. [Abs]

  275. Kohno, K., Oshiro, T., Kishine, H., Wada, M., Takeda, H., Ihara, N., Imamoto, F., Kano, Y. and Schlessinger, D. (1997). Construction and characterization of a rad52 double mutant as a host for YAC libraries. Gene. 188: 175-181. [Abs]

  276. Palmieri, G., Miano, M.G., Casamassimi, A., Kohno, K., Schlessinger, D., D'Urso, M. and Featherstone, T. (1997). Construction of a pilot human YAC library in a recombination-defective yeast strain. Gene 188 (2): 169-174. [Abs]

  277. Esposito, T., Ciccodicola, A., Flagiello, L., Matarazzo, M.R., Migliaccio, C., Cifarelli, R.A., Visone, R., Camponile, C., Mazzarella, R., Schlessinger, D., D'Urso, M. and D'Esposito, M. (1997). Expressed STSs and transcription of human Xq28. Gene. 187: 185-191. [Abs]

  278. D'Esposito, M., Matarazzo, M., Ciccodicola, A., Strazzullo, M., Mazzarella, R., Quaderi, N., Fujiwara, H., Ko, M.S., Rowe, L.B., Rocchi, M., Archidiacono, N., Ricco, A., Schlessinger, D., and D'Urso, M. (1997). Differential expression pattern of XqPAR-linked genes Sybl1 and IL9R correlates with the structure and evolution of the region. Hum. Mol. Genet. 6: 1917-1923. [Abs]

  279. Nagaraja, R., MacMillan, S., Kere, J., Jones, C., Cox, S., Schmatz, M., Terrell, J., Shoemaker, M., Jermak, C., Hott, C., Masisi, M., Mumm, S., Srivastava, A., Pilia, G., Featherstone, T., Mazzarella, R., Kesterson, S., McCauley, B., Railey, B., Burough, F., Nowotny, V., States, D., Brownstein, B. and Schlessinger, D. (1997). X chromosome map at 75 kb STS resolution, revealing extremes of recombination and GC content. Genome Research 7: 210-222. [Abs]

  280. Mumm, S., Molini, B., Terrell, J., Srivastava, A., and Schlessinger, D. (1997). Evolutionary features of the 4 Mb Xq21.3 XY homology region revealed by a map at 60 kb resolution.Genome Research 7: 307-314. [Abs]

  281. Porta, G., MacMillan, S., Nagaraja, R., Mumm, S., Zucchi, I., Pilia, G., Maio, S., Featherstone, T., and Schlessinger, D. (1997). 4.5 Mb YAC STS contig at 50 kb resolution, spanning Xq25 deletions in two patients with lymphoproliferative syndrome. Genome Research 7: 27-36. [Abs]

  282. Mumm, S., Whyte, M.P., Thakker, R.V., Buetow, K.H., and Schlessinger, D. (1997). mtDNA analysis shows common ancestry in two kindreds with X-linked recessive hypoparathyroidism and reveals a heteroplasmic silent mutation. Am. J. Hum. Genet. 60: 153-159. [Abs]

  283. Lindsay, S., Ireland, M., O'Brien, O., Clayton-Smith, J., Hurst, J.A., Mann, J., Cole, T., Sampson, J., Slaney, S., Schlessinger, D., Burn, J., Pilia, G. (1997). Large scale deletions in the GPC3 gene may account for a minority of cases of Simpson-Golabi-Behmel syndrome. J. Med. Genet. 34: 480-483. [Abs]

  284. Grieff, M., Mumm, S., Waeltz, P., Mazzarella, R., Whyte, M.P., Thakker, R.V., and Schlessinger, D. (1997). Expression and cloning of the human X-linked hypophosphatemia gene cDNA. Biochem. Biophy. Res. Communications 231: 635-639. [Abs]

  285. Mazzarella, R., Pengue, G., Yoon, J., Jones, J., and Schlessinger, D. (1997). Differential expression of XaP-5, a candidate disease gene. Genomics. 45: 216-219. [Abs]

  286. Ferrero, G.B., Gebbia, M., Pilia, G., Pilia, G., Witte, D., Peier, A., Hopkin, R.J., Shaffer, L., Schlessinger, D., and Casey, B. (1997). A submicroscopic deletion in Xq26 associated with familial defects of left-right asymmetry. Am. J. Hum. Genet. 61: 395-401. [Abs]

  287. Ezer, S., Schlessinger, D., Srivastava, A. and Kere, J. (1997). Anhidrotic ectodermal gene protein expressed in MCF-7 cells associates with cell membrane and induces rounding. Hum. Mol. Genet. 6 (9): 1581-1587. [Abs]

  288. Mazzarella, R. and Schlessinger, D. (1997). Duplication and distribution of repetitive elements and "unique" repeats in the human genome. Gene 205: 29-38. [Abs]

  289. Srivastava, A.K., Pispa, J., Hartung, A.J., Du, Y., Ezer, S., Jenks, T., Shimada, T., Pekkanen, M., Mikkola M.L., Ko, M.S.H., Thesleff, I., Kere, J., and Schlessinger, D. (1997). The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains. PNAS 94: 13069-13074. [Abs]

  290. Gebbia M., Ferrero GB, Pilia G, Aylsworth AS., Penman-Splitt M., Bird LM, Bamforth JS, Burn J, Schlessinger D., Nelson DL, Casey B. (1997) X-linked situs abnormalities result from mutations in ZIC3. Nat. Genet. 17 (3): 305-309. [Abs]

  291. Schlessinger, D., Nagaraja R. (1998) Impact and Implications of Yeast and Human Artificial Chromosomes. Ann. Med. 30: 186-191. [Abs]

  292. Dixon P., Christie P., Wooding C.; Trump D., Grief M.; Holm I.; Gertner J.; Schmidtke J.; Shah B.; Shaw N.; Smith C.; Tau C.; Schlessinger D.; Whyte M.; Thakker R. (1998). Mutational analysis of the PEX gene in X-linked Hypophosphataemia. J. Clin. Endocrinol. Metab. 83: 3615-3623. [Abs]

  293. Nagaraja R., Jermak C., Trusgnich M., Yoon J., MacMillan S., McCauley B., Brownstein B., Schlessinger D. (1998). YAC/STS map of 15 Mb of Xp21.3-p11.3, at 100 kb resolution, with refined comparisons of genetic distances and DMD structure. Gene. 215: 259-267. [Abs]

  294. Trump D., Dixon PH., Mumm S., Wooding C., Davies KE., Schlessinger D., Whyte MP., Thakker, RV. (1998). Localisation of X-linked Recessive Idiopathic Hypoparathyroidism to a 1.5 Mb region on Xq26-q-27. J. Med. Genet. 35: 905-909. [Abs]

  295. Mazzarella R., Pengue G., Jones J., Jones C., Schlessinger D. (1998). Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25. Genomics. 48: 157-162. [Abs]

  296. Montonen O., Ezer S., Saarialho-Kere U.K. Herva R., Karjalainen-Lindsberg M.L., Kaitila I., Schlessinger D., Srivastava A.K., Thesleff I. Kere J. (1998). The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone. J. Histochem. Cytochem. 46: 281-289. [Abs]

  297. Torigoe K., Harada T., Kusaba H., Uchiumi T., Kohno K., Green E.D., Scherer S.W., Tsui L.C., Schlessinger D., Kuwano M., Wada M. (1998). Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1. Genomics. 49: 14-22. [Abs]

  298. Huber R., Schlessinger D., Pilia G. (1998). Multiple Sp1 sites efficiently drive transcription of the TATA-less promoter of the human glypican 3 (GPC3) gene. Gene. 214: 35-44. [Abs]

  299. Schlessinger D., Ko M.S.H. (1998). Developmental genomics and its relation to aging. Genomics. 52: 113-118. [Abs]

  300. Nagaraja R, MacMillan S., Jones C., Masisi M., Pengue G., Porta G., Miao S., Casamassimi A., D'Urso M., Brownstein B., Schlessinger D. (1998). Integrated YAC/STS physical and genetic map of 22.5 Mb of human Xq24- q26 at 56-kb inter-STS resolution. Genomics. 52: 247-266. [Abs]

  301. Mazzarella R., Schlessinger D. (1998). Pathological consequences of sequence duplications in the human genome. Genome Res. 8: 1007-1021. [Abs]

  302. Huber R., Hansen R.S., Strazzullo M., Pengue G., Mazzarella R., D'Urso M., Schlessinger D., Pilia G., Gartler S.M., D'Esposito M. (1999). DNA methylation in transcriptional repression of two differentially expressed X-linked genes, GPC3 and SYBL1. Proc. Natl. Acad. Sci. 96: 616-621. [Abs]

  303. Stoddart K.L., Jermak C., Nagaraja R., Schlessinger D., Bech-Hansen, N.T (1999). Physical map covering a 2Mb region in human xp11.3 distal to CX6849. Gene. 227: 111-116. [Abs]

  304. Lin H., Huber R., Schlessinger D., Morin P.J. (1999). Frequent silencing of the GPC3 gene in ovarian cancer cell lines. Cancer Res, 59:807-810. [Abs]

  305. Srivastava, A.K., McMillan, S., Jermak., C., Shomaker, M., Copeland-Yates, S.A., Sossey-Alaoui, K., Mumm, S., Schlessinger, D. and Nagaraja, R (1999). Integrated STS/YAC physical, genetic, and transcript map of human Xq21.3 to q23/q24 (DXS1203-DXS1059). Genomics. 58:188-201.[Abs]

  306. Cocchia M, Huber R, Pantano S, Chen EY, Forabosco A, Ko MSH, and Schlessinger D. (2000). PLAC1, an Xq26 gene with placenta-specific expression. Genomics, 68:305-312. [Abs]

  307. Cocchia, M., Kouprina, N., Kim, S.J., Larionov, V., Schlessinger, D., Nagaraja, R. (2000). Recovery and potential utility of YACs as circular YACs/BACs. Nucleic Acids Res. 28(17):E81. [Abs]

  308. Ciccodicola A, D'Esposito M, Esposito T, Gianfrancesco F, Migliaccio C, Miano MG, Matarazzo MR, Vacca M, Franze A, Cuccurese M, Cocchia M, Curci A, Terracciano A, Torino A, Cocchia S, Mercadante G, Pannone E, Archidiacono N, Rocchi M, Schlessinger D, D'Urso M. (2001). Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region. Hum Mol Genet, 9(3):395-401. [Abs]

  309. Kargul GJ, Nagaraja R, Shimada T, Grahovac MJ, Lim MK, Nakashima H, Waeltz P, Ma P, Chen EY, Schlessinger D, and Ko MSH. (2000). Eleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNA. Genome Res., 10: 916-923.[Abs]

  310. Khan S, Blackburn M, Mao DL, Huber R, Schlessinger D, Fant M. (2001). Glypican-3 (GPC3) expression in human placenta: localization to the differentiated syncytiotrophoblast. Histol Histopathol, 16(1):71-78.[Abs]

  311. Crisponi, L., Deiana, M., Loi, A., Chiappe, F., Uda, M., Amati, P., Bisceglia, L., Zelante, L., Nagaraja, R., Porcu, S., Ristaldi, M.S., Marzella, R., Rocchi, M., Nicolino, M., Lienhardt-Roussie, A., Nivelon, A., Verloes, A., Schlessinger, D., Gasparini, P., Bonneau, D., Cao, A., Pilia, G. (2001). The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. Nat Genet. 27(2):159-166. [Abs]

  312. Schlessinger D, Van Zant G. (2001). Does functional depletion of stem cells drive aging? Mech Ageing Dev, 122(14):1537-1553. [Abs]

  313. Mumm S, Herrera L, Waeltz PW, Scardovi A, Nagaraja R, Esposito T, Schlessinger D, Rocchi M, Forabosco A. (2001). X/autosomal translocations in the Xq critical region associated with premature ovarian failure fall within and outside genes. Genomics, 76(1-3):30-36. [Abs]

  314. Srivastava AK, Durmowicz MC, Hartung AJ, Hudson J, Ouzts LV, Donovan DM, Cui CY, Schlessinger D. (2001). Ectodysplasin-A1 is sufficient to rescue both hair growth and sweat glands in Tabby mice. Hum Mol Genet, 10(26):2973-2981. [Abs]

  315. Toretsky JA, Zitomersky NL, Eskenazi AE, Voigt RW, Strauch ED, Sun CC, Huber R, Meltzer SJ, Schlessinger D. (2001). Glypican-3 expression in Wilms tumor and hepatoblastoma. J Pediatr Hematol Oncol, 23(8):496-499. [Abs]

  316. Chiao E, Fisher P, Crisponi L, Deiana M, Dragatsis I, Schlessinger D, Pilia G, Efstratiadis A. (2002). Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling. Dev Biol, 243(1):185-206. [Abs]

  317. Durmowicz MC, Cui CY, Schlessinger D. (2002). The EDA gene is a target of, but does not regulate Wnt signaling. Gene 285(1-2):203-211. [Abs]

  318. Cui CY, Durmowicz M, Tanaka TS, Hartung AJ, Tezuka T, Hashimoto K, Ko MS, Srivastava AK, Schlessinger D. (2002). EDA targets revealed by skin gene expression profiles of wild-type, Tabby and Tabby EDA-A1 transgenic mice. Hum Mol Genet, 11(15):1763-1773. [Abs]

  319. Schlessinger D, Herrera L, Crisponi L, Mumm S, Percesepe A, Pellegrini M, Pilia G, Forabosco A. (2002). Genes and translocations involved in POF. Am J Med Genet, 111(3):328-333. [Abs]

  320. Fant M, Weisoly DL, Cocchia M, Huber R, Khan S, Lunt T, Schlessinger D. (2002). PLAC1, a trophoblast-specific gene, is expressed throughout pregnancy in the human placenta and modulated by keratinocyte growth factor. Mol Reprod Dev, 63(4):430-436. [Abs]

  321. Galaviz-Hernandez C, Stagg C, de Ridder G, Tanaka TS, Ko MS, Schlessinger D, Nagaraja R. (2003). Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis. Gene, 309(2):81-89. [Abs]

  322. Cui CY, Durmowicz M, Ottolenghi C, Hashimoto T, Griggs B, Srivastava AK, Schlessinger D. (2003) Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential formation of two types of mouse hair follicles. Hum Mol Genet, 12(22):2931-2940. [Abs]

  323. Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MSH. (2003). Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol, 1:410-419. [Abs]

  324. Uda M, Ottolenghi C, Crisponi L, Garcia JE, Deiana M, Kimber W, Forabosco A, Cao A, Schlessinger D, Pilia G. (2004) Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development. Hum Mol Genet, 13(11):1171-1181. [Abs]

  325. Crisponi L, Uda M, Deiana M, Loi A, Nagaraja R, Chiappe F, Schlessinger D, Cao A, Pilia G. (2004) FOXL2 inactivation by a translocation 171 kb away: analysis of 500 kb of chromosome 3 for candidate long-range regulatory sequences. Genomics, 83(5):757-764. [Abs]

  326. Andrew Nesbit M, Bowl MR, Harding B, Schlessinger D, Whyte MP, Thakker RV. (2004) X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase. Genomics. 84(6):1060-1070. [Abs]

  327. Kim AJ, Lee CS, Schlessinger D. (2004) Bex3 associates with replicating mitochondria and is involved in possible growth control of F9 teratocarcinoma cells. Gene. ;343(1):79-89. [Abs]

  328. Ottolenghi C, Uda M, Hamatani T, Crisponi L, Garcia JE, Ko M, Pilia G, Sforza C, Schlessinger D, Forabosco A. (2004) Aging of oocyte, ovary, and human reproduction. Ann NY Acad Sci. 1034:117-131. [Abs]

  329. Herrera L, Ottolenghi C, Garcia-Ortiz JE, Pellegrini M, Manini F, Ko MS, Nagaraja R, Forabosco A, Schlessinger D. (2005) Mouse ovary developmental RNA and protein markers from gene expression profiling. Dev Biol. 279(2):271-290. [Abs]

  330. Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glockner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Muller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR. (2005) The DNA sequence of the human X chromosome. Nature. 434(7031):325-337. [Abs]

  331. Ottolenghi C, Omari S, Garcia-Ortiz JE, Uda M, Crisponi L, Forabosco A, Pilia G, Schlessinger D. (2005) Foxl2 is required for commitment to ovary differentiation. Hum Mol Genet. 14(14):2053-2062. [Abs]

  332. Cui CY, Smith JA, Schlessinger D, Chan CC. (2005) X-linked anhidrotic ectodermal dysplasia disruption yields a mouse model for ocular surface disease and resultant blindness. Am J Pathol. 167(1):89-95. [Abs]

  333. Bowl MR, Nesbit MA, Harding B, Levy E, Jefferson A, Volpi E, Rizzoti K, Lovell-Badge R, Schlessinger D, Whyte MP, Thakker RV. (2005) An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism. J Clin Invest. 115(10):2822-2831. [Abs]

  334. Hashimoto T, Cui CY, Schlessinger D. (2006) Repertoire of mouse ectodysplasin-A (EDA-A) isoforms. Gene. 371(1):42-51. [Abs]

  335. Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D. (2006) Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci USA. 103(24):9142-9147. [Abs]

  336. Cui CY, Schlessinger D. EDA signaling and skin appendage development. (2006) Cell Cycle. 5(21):2477-2483. [Abs]

  337. Pilia G, Chen WM, Scuteri A, Orru M, Albai G, Dei M, Lai S, Usala G, Lai M, Loi P, Mameli C, Vacca L, Deiana M, Olla N, Masala M, Cao A, Najjar SS, Terracciano A, Nedorezov T, Sharov A, Zonderman AB, Abecasis GR, Costa P, Lakatta E, Schlessinger D. (2006) Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet. 2(8):e132. [Abs]

  338. Costa PT Jr, Terracciano A, Uda M, Vacca L, Mameli C, Pilia G, Zonderman AB, Lakatta E, Schlessinger D, McCrae RR. (2007) Personality traits in Sardinia: testing founder population effects on trait means and variances. Behav Genet. 37(2):376-387. [Abs]

  339. Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orru M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 3(7):e115. [Abs]

  340. Balaci L, Spada MC, Olla N, Sole G, Loddo L, Anedda F, Naitza S, Zuncheddu MA, Maschio A, Altea D, Uda M, Pilia S, Sanna S, Masala M, Crisponi L, Fattori M, Devoto M, Doratiotto S, Rassu S, Mereu S, Giua E, Cadeddu NG, Atzeni R, Pelosi U, Corrias A, Perra R, Torrazza PL, Pirina P, Ginesu F, Marcias S, Schintu MG, Giacco GS, Manconi PE, Malerba G, Bisognin A, Trabetti E, Boner A, Pescollderungg L, Pignatti PF, Schlessinger D, Cao A, Pilia G. (2007) IRAK-M is involved in the pathogenesis of early-onset persistent asthma. Am J Hum Genet. 80(6):1103-1114. [Abs]

  341. Kouprina N, Noskov VN, Pavlicek A, Collins NK, Schoppee Bortz PD, Ottolenghi C, Loukinov D, Goldsmith P, Risinger JI, Kim JH, Westbrook VA, Solomon G, Sounders H, Herr JC, Jurka J, Lobanenkov V, Schlessinger D, Larionov V. (2007) Evolutionary diversification of SPANX-N sperm protein gene structure and expression. PLoS ONE. 2:e359. [Abs]

  342. Ottolenghi C, Uda M, Crisponi L, Omari S, Cao A, Forabosco A, Schlessinger D. (2007) Determination and stability of sex. Bioessays. 29(1):15-25. [Abs]

  343. Ottolenghi C, Colombino M, Crisponi L, Cao A, Forabosco A, Schlessinger D, Uda M. (2007) Transcriptional control of ovarian development in somatic cells. Semin Reprod Med. 25(4):252-263. [Abs]

  344. Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D. (2007) Lymphotoxin-{beta} regulates periderm differentiation during embryonic skin development. Hum Mol Genet. [Epub ahead of print]. [Abs]

IRP Home     What's New     Contact Us     Accessibility     Disclaimer     Privacy     Site Search     Site Map     NIA Home    
NIH logo-link to NIH Home Page DHHS logo-link to DHHS Web Site FirstGov logo-link to FirstGov Web Site
Updated: Thursday October 11, 2007