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National Institute on Aging
National Institutes of Health |
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Research Programs Intramural
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| Magnetic Resonance Imaging and Spectroscopy Section |
| Richard Spencer, Ph.D., M.D., F.A.C.P.,Chief Senior Investigator |
| Overview:
Basic research includes spectroscopic and imaging studies of connective tissue biophysics (chondrocytes in culture, tissue engineered constructs, and native cartilage in explants and in vivo), spectroscopic studies of muscle metabolism under a variety of pharmacologic and physiologic conditions, and methodology development in imaging and spectroscopy. Translational studies include investigation of brain metabolites, muscle bioenergetics, and cartilage biophysics. |
Magnetic resonance instrumentation within the Section consists of a triple-resonance vertical wide-bore Bruker DMX 400 Avance system with microimaging and solids capability and a double-resonance Bruker 7T/30 cm DBX system. In addition, we have full access to and extensively use the research-dedicated whole-body 3T Philips Achieva MRI system, equipped with homo- and heteronuclear spectroscopic capabilities, sited in our affiliated Clinical Research Branch at Harbor Hospital. |
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