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National Institute on Aging
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Intramural

Magnetic Resonance Imaging and Spectroscopy Section
Richard Spencer, Ph.D., M.D., F.A.C.P.,Chief
Senior Investigator
Overview:

Basic research includes spectroscopic and imaging studies of connective tissue biophysics (chondrocytes in culture, tissue engineered constructs, and native cartilage in explants and in vivo), spectroscopic studies of muscle metabolism under a variety of pharmacologic and physiologic conditions, and methodology development in imaging and spectroscopy.   Translational studies include investigation of brain metabolites, muscle bioenergetics, and cartilage biophysics.

Magnetic resonance instrumentation within the Section consists of a triple-resonance vertical wide-bore Bruker DMX 400 Avance system with microimaging and solids capability and a double-resonance Bruker 7T/30 cm DBX system.  In addition, we have full access to and extensively use the research-dedicated whole-body 3T Philips Achieva MRI system, equipped with homo- and heteronuclear spectroscopic capabilities, sited in our affiliated Clinical Research Branch at Harbor Hospital.  

  • Additional MRI Section Links
  • MRI Section - Personnel
  • MRI in Tissue Engineering, Sunrise Course Schedule--ISMRM Honolulu, 2009 - http://www.ismrm.org/09/SS_Tissue.htm
  • Lecture, MRI and Tissue Engineering--ISMRM Toronto, 2008 - (PowerPoint)
  • Lecture, MRI Hardware for Clinicians--ISMRM Miami, 2005 - (PowerPoint)
  • Book Chapter, Introduction to MRI Hardware, 2005 - (pdf)
  • Lecture, MRI Signal Processing--ISMRM Japan, 2004 - (PowerPoint)
  • Syllabus, MRI Signal Processing--ISMRM Japan, 2004 - (pdf)
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Updated: Monday January 03, 2011