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Patrice Jean-Luc Morin, Ph.D.

  1. Morin, P., Bédard, J. and Lefebvre, G.M. (1990) Certain aspects of the pH dependence of triggering in Bacillus megaterium spores. Current Microbiology 21, 349-354.
  2. Morin, P.J. and Gilmore, T.D. (1992) The C-terminus of the NF-kB p50 precursor and an IkB isoform contain transcription activation domains. Nucleic Acids Res. 20, 2453-2458.[Abs]
  3. Morin, P.J., Subramanian, G.S. and Gilmore, T.D. (1992) AAT1, a gene encoding a mitochondrial aspartate aminotransferase in Saccharomyces cerevisiae. Biochimica et Biophysica Acta 1171, 211-214.[Abs]
  4. Morin, P.J., Subramanian, G.S. and Gilmore, T.D. (1993) GAL4-IkBa and GAL4-IkBg activate transcription by different mechanisms. Nucleic Acids Res. 21, 2157-2163.[Abs]
  5. Gilmore, T.D. and Morin, P.J. (1993) The IkB proteins: members of a multifunctional family. Trends in Genetics 9, 427-433.[Abs]
  6. Morin, P.J., Downs, J.A., Snodgrass, A. M. and Gilmore, T.D. (1995) Genetic analysis of growth inhibition by GAL4-IkB-a in Saccharomycescerevisiae. Cell Growth and Differentiation 6, 789-798.[Abs]
  7. Morin, P.J., Vogelstein, B. and Kinzler, K.W. (1996) Apoptosis and APC in colorectal tumorigenesis. Proc. Natl. Acad. Sci. USA 93, 7950-7954.[Abs]
  8. Huang, J., Papadopoulos, N., McKinley, A.J., Farrington, S.M., Curtis, L.J., Wyllie, A.H., Zheng, S., Willson, J.K.V., Markowitz, S.D., Morin, P.J., Kinzler, K.W., Vogelstein, B. and Dunlop, M.G. (1996) APC mutations in colorectal tumors with mismatch repair deficiency. Proc. Natl. Acad. Sci. USA 93, 9049-9054.[Abs]
  9. Korinek, V., Barker, N., Morin, P.J., van Wichen, D., de Weger, R., Kinzler, K.W., Vogelstein, B. and Clevers, H. (1997) Constitutive transcriptional activation by a b-catenin/Tcf complex in APC -/- colon carcinoma. Science 275, 1784-1787.[Abs]
  10. Morin, P.J., Sparks, A.B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B. and Kinzler, K.W. (1997) Activation of b-catenin-Tcf signaling in colon cancer by mutations in b-catenin or APC. Science 275, 1787-1790.[Abs]
  11. Chan*, T., Morin*, P.J., Vogelstein, B. and Kinzler, K.W. (1998) Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc. Natl. Acad. Sci. USA 95, 681-686.[Abs] *These authors contributed equally to this work.
  12. Sparks*, A.B., Morin*, P.J., Vogelstein, B. and Kinzler, K.W. (1998). Mutational analysis of the APC/b-catenin/Tcf pathway in colorectal cancer. Cancer Research 58, 1130-1134.[Abs] *These authors contributed equally to this work.
  13. He, T.-C., Sparks, A.B., Rago, C., Hermeking, H., Zawel, L., da Costa L.T., Morin, P.J., Vogelstein, B. and Kinzler, K.W. (1998) Identification of c-MYC as a target of the APC pathway. Science 281, 1509-1512.[Abs]
  14. Lin H., Huber R., Schlessinger, D and Morin, P.J. (1999) Frequent silencing of GPC3 in ovarian cancer cell lines. Cancer Res. 59, 807-810.[Abs]
  15. da Costa, L.T., He, T.-C., Yu, J., Sparks, A.B., Morin, P.J., Polyak, K., Laken, S., Vogelstein, B. and Kinzler, K.W. (1999) CDX2 is mutated in a colorectal cancer with normal APC/b-catenin signaling. Oncogene. 18, 5010-5014.[Abs]
  16. Barker, N., Morin, P.J. and Clevers H. (1999) The Yang-Yang of TCF/b-catenin signaling. In: G.F. Vande Woude and G. Klein (Eds.) Advances in Cancer Research. Academic Press, San Diego, 1-24.
  17. Furlong, M.T., Hough, C.D., Sherman-Baust, C.A., Pizer, E.S. and Morin, P.J. (1999) Evidence that ovarian cancer cell line SW626 may be of colonic origin. J. Natl. Cancer Inst. 91, 1327-1328.[Abs]
  18. Lal, A., Lash, A.E., Altschul, A.F., Velculescu, V.E., Zhang, L., McLendon, R.E., Marra, M.A., Prange, C., Morin, P.J., Papadopoulos, N., Vogelstein B., Kinzler, K.W., Strausberg, R.L., and Riggins, G.J. (1999) A public database for quantitative gene expression analysis in human cancers. Cancer Res. 59, 5403-5407.[Abs]
  19. Morin, P.J. (1999) b-catenin signaling and cancer. BioEssays 21, 1021-1030.[Abs]
  20. Furlong, M.T., and Morin, P.J. (2000) Rare activation of the TCF/b-catenin pathway in ovarian cancer. Gynecological Oncology 77, 97-104.[Abs]
  21. Lin, H., Pizer, E.S. and Morin, P.J. (2000) A frequent deletion polymorphism on chromosome 22q13 identified by representational difference analysis of ovarian cancer. Genomics 69, 391-394.[Abs]
  22. Hough, C.D., Sherman-Baust, C.A., Pizer, E.S., Montz, F.J., Im, D.D., Rosenshein, N.B., Cho, K.R., Riggins, G.J. and Morin, P.J. (2000) Large-scale serial analysis of gene expression reveals gene differentially expressed in ovarian cancer. Cancer Res. 60(22), 6281-6287.[Abs]
  23. Sasaki, C.Y., Lin H.J. Morin, P.J. and Longo, D.L. (2000) Truncation of the extracellular region abrogates cell contact but retains the growth-suppressive activity of E-cadherin. Cancer Res. 60(24), 7057-7065.[Abs]
  24. Hough, C.D., Cho K.R. and Morin, P.J. (2001) Analysis of genes highly overexpressed in ovarian cancer by real-time RT-PCR. Cancer Res. 61, 3869-3876. [Abs]
  25. Lin, H. and Morin, P.J. (2001) A novel homozygous deletion at chromosomal band 6q27 in an ovarian cancer cell line delineates the position of a putative tumor suppressor gene. Cancer Lett. 173, 63-70. [Abs]
  26. Morin, P.J. (2002) APC/b-catenin pathway. In Encyclopedic reference of Cancer Manfred Schwab, editor. Springer-Verlag, Heidelberg. 70-73.
  27. Morin, P.J. and Pizer, E. (2002) Ovarian Cancer. In Encyclopedic reference of Cancer Manfred Schwab, editor. Springer-Verlag, Heidelberg. 654-656.
  28. Caldwell, M.C., Hough, C.D., Furer, S., Morin, P.J. and Gorospe, M. (2002) Serial Analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFa cytotoxicity. Oncogene 21, 929-936. [Abs]
  29. Sawiris, G.P., Sherman-Baust, C.A., Becker, K.G., Cheadle, C., Teichberg, D., Morin, P.J. (2002) The Ovachip, Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer. Cancer Research, 62, 2923-2928. [Abs] -- [Ovachip Gene List (excel)]

  30. Riggins, G.J. and Morin P.J. (2002) Gene expression profiling in Cancer. In: The Genetic Basis of Human Cancer, Vogelstein B. and Kinzler K.W. Eds. McGraw Hill, New York. 131-141
  31. Boon, K., Osorio, E.C., Greenhut, S.F., Schaefer, C.F., Shoemaker, J., Polyak, K., Morin, P.J., Buetow, K.H., Strausberg, R.L., De Souza, S.J., Riggins, G.J. (2002) An anatomy of normal and malignant gene expression. Proc. Natl. Acad. Sci. USA 99(17), 11287-11292. [Abs]

  32. Yang, Y.A., Han, W.F., Morin, P.J., Chrest, F.J., Pizer, E.S. (2002) Activation of fatty acid synthesis during neoplasic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp. Cell Res. 279(1), 80-90. [Abs]

  33. Morin, P.J. (2002) Renal cell carcinoma: taking care of business. Cancer Biol. Ther. 1(5), 537-538.

  34. Yang, Y.A., Morin, P.J., Han, W.F., Chen, T., Bornman, D.M., Gabrielson, E.W., Pizer, E.S. (2003) Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c.Exp. Cell Res. 282(2), 132-137. [Abs]

  35. Wu, S., Morin, P.J., Maouyo, D., Sears, C.L. (2003) Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation. Gastroenterology. 124(2), 392-400. [Abs]

  36. Morin, P.J., Weeraratna, A.T. (2003) Wnt signaling in human cancer. Cancer Treat Res. 115, 169-187.

  37. Morin, P.J., Weeraratna, A.T. (2003) The APC tumor suppressor pathway. Methods Mol. Biol. 222, 21-40.

  38. Sherman-Baust, C.A., Weeraratna, A.T., Rangel, L.B., Pizer, E.S., Cho, K.R., Schwartz, D.R., Shock, T., Morin, P.J. (2003) Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. Cancer Cell. 3(4), 377-386. [Abs]

  39. Rangel, L.B., Agarwal, R., D'Souza, T., Pizer, E.S., Alo, P.L., Lancaster, W.D., Gregoire, L., Schwartz, D.R., Cho, K.R., Morin, P.J. (2003) Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. Clin. Cancer Res. 9(7), 2567-2575. [Abs]

  40. Buckhaults, P., Zhang, Z., Chen, Y.C., Wang, T.L., St Croix, B., Saha, S., Bardelli, A., Morin, P.J., Polyak, K., Hruban, R.H., Velculescu, V.E., Shih, I-M. (2003) Identifying tumor origin using a gene expression-based classification map. Cancer Res. 63(14), 4144-4149. [Abs]

  41. Morin, P.J. (2003) Drug resistance and the microenvironment: nature and nurture. Drug Resist. Updat.6(4), 169-172. [Abs]

  42. Rangel, L.B., Sherman-Baust, C.A., Wernyj, R.P., Schwartz, D.R., Cho, K.R., Morin, P.J. (2003) Characterization of novel human ovarian cancer-specific transcripts (HOSTs) identified by serial analysis of gene expression. Oncogene. 22(46), 7225-7232. [Abs]

  43. Weeraratna, A.T., Becker, D., Carr, K.M., Duray, P.H., Rosenblatt, K.P., Yang, S., Chen, Y., Bittner, M., Strausberg, R.L., Riggins, G.J., Wagner, U., Kallioniemi, O.P., Trent, J.M., Morin, P.J., Meltzer, P.S. (2004) Generation and analysis of melanoma SAGE libraries: SAGE advice on the melamona transcriptome. Oncogene. 18(23), 2264-2274. [Abs]

  44. Rangel, L.B., Agarwal, R., Sherman-Baust, C.A., de Mello-Coelho, V., Pizer, E.S., Ji, H., Taub, D.D., Morin, P.J. (2004) Anomalous expression of the HLA-DR a and b chains in ovarian and other cancer. Cancer Biol. Ther. 3(10). [Abs]

  45. Wernyj, R.P., Morin, P.J. (2004) Molecular mechanisms of platinum resistance: still searching for the Achilles' heel. Drug Resist. Updat. 7(4-5), 227-232. [Abs]

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Updated: Thursday October 11, 2007